A5100971298- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Chronic Kidney Disease and Diabetes
- Gastrointestinal motility and disorders
- Diabetes Management and Research
- Cancer Genomics and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes and associated disorders
- Ophthalmology and Visual Impairment Studies
- Demographic Trends and Gender Preferences
- Breast Cancer Treatment Studies
- Corneal surgery and disorders
- Atrial Fibrillation Management and Outcomes
- Blood Pressure and Hypertension Studies
- Cardiac Arrhythmias and Treatments
- Gut microbiota and health
- Cardiovascular Disease and Adiposity
- Aortic Disease and Treatment Approaches
- GDF15 and Related Biomarkers
- Cardiac Ischemia and Reperfusion
- Celiac Disease Research and Management
- Pancreatic function and diabetes
- Dialysis and Renal Disease Management
- Traditional Chinese Medicine Studies
Tongji University
2024-2025
Qingdao University
2023-2025
Affiliated Hospital of Qingdao University
2023-2025
Shanghai Eye Disease Prevention & Treatment Center
2024-2025
Daping Hospital
2024-2025
Sanda University
2024
Yangzhou University
2024
Xuzhou Medical College
2012-2024
Chinese PLA General Hospital
2024
Air Force Medical University
2024
This cohort study examines whether there is a temporal association between SARS-CoV-2 infection and the development of islet autoimmunity among Australian children with first-degree relative type 1 diabetes.
Cardiac magnetic resonance (CMR) T1 mapping and tissue-tracking strain analysis are useful quantitative techniques that can characterize myocardial tissue mechanical alterations, respectively, in patients with early diabetic cardiomyopathy. The purpose of this study was to assess the left ventricular value, extracellular volume fraction (ECV), systolic asymptomatic type 2 diabetes mellitus (T2DM) their underlying relationships clinical parameters. We recruited 50 T2DM (mean age: 55 ± 7...
JOURNAL/nrgr/04.03/01300535-202409000-00042/figure1/v/2024-01-30T062302Z/r/image-tiff Parkinson's disease is a neurodegenerative characterized by motor and gastrointestinal dysfunction. Gastrointestinal dysfunction can precede the onset of symptoms several years. Gut microbiota dysbiosis involved in pathogenesis disease, whether it plays causal role dysfunction, mechanism underlying this potential effect, remain unknown. CCAAT/enhancer binding protein β/asparagine endopeptidase (C/EBPβ/AEP)...
Continuous glucose monitoring (CGM) can detect early dysglycemia in older children and adults with presymptomatic type 1 diabetes (T1D) predict risk of progression to clinical onset. However, CGM data for very young at greatest disease are lacking. This study aimed investigate the use measured being longitudinally observed Australian Environmental Determinants Islet Autoimmunity (ENDIA) from birth age 10 years.
Abstract Background Research into the acute kidney disease (AKD) after ischemic stroke (AIS) is rare, and how clinical features influence its prognosis remain unknown. We aim to employ interpretable machine learning (ML) models study AIS clarify decision-making process in identifying risk of mortality. Methods conducted a retrospective cohort involving patients from January 2020 June 2021. Patient data were randomly divided training test sets. Eight ML algorithms employed construct...
Background Data on the epidemiology of hypertension in Chinese non-dialysis chronic kidney disease (CKD) patients are limited. The aim present study was to investigate prevalence, awareness, treatment, and control CKD through a nationwide, multicenter China. Methods survey performed 61 tertiary hospitals 31 provinces, municipalities, autonomous regions China (except Hong Kong, Macao, Taiwan). Trained physicians collected demographic clinical data measured blood pressure (BP) using...
Cardiovascular magnetic resonance (CMR)-derived extracellular volume (ECV) and tissue tracking strain analyses are proposed as non-invasive methods for quantifying myocardial fibrosis deformation. This study sought (1) to histologically validate ECV against the collagen fraction (CVF) measured from samples of patients undergoing heart transplantation (2) detect correlations between systolic histological CVF in transplantation. A total 12 dilated cardiomyopathy (DCM) 10 ischaemic (ICM)...
Currently, no relevant studies have reported a relationship between astigmatism and peripheral refraction (PR). We aimed to describe the association PR relative (RPR) with in Chinese children mild moderate myopia, provide new insights into influence of astigmatism. Three-hundred-and-seven (6-14 years old) from Shanghai were included this study. The RPR measured using multispectral topography (MRT). Cycloplegic was an autorefractor (KR-8900, Topcon), whereas axial length ocular biological...
Early Triple negative breast cancer (eTNBC) is the subtype with worst outcome. Circulating tumor DNA (ctDNA) shown to predict prognosis of cancer, but its utility in eTNBC remains unclear. 130 stage II-III female patients receiving neoadjuvant chemotherapy (NAC) have been enrolled prospectively and subjected ctDNA analysis. at post-NAC (pre-surgery) post-surgery, not baseline, associated worse prognosis. A threshold 1.1% maximum variant allele frequency baseline stratifies different relapse...
Little is known about acute kidney injury (AKI) and disease (AKD) in patients with chronic obstructive pulmonary (COPD) COPD mortality based on the acute/subacute renal injury. This study develops machine learning models to predict AKI, AKD, patients, utilizing web applications for clinical decisions. We included 2,829 inpatients from January 2016 December 2018. Data were split into 80% training 20% testing. Eight algorithms used, model performance was evaluated using various metrics. SHAP...
Background: Mesenchymal stem cells (MSCs) were able to restore ovarian function in premature insufficiency (POI), which can be largely attributed the paracrine effects of MSCs therapy. However, and mechanism MSC-derived exosomes transplantation for POI are not fully understood. Objective: To investigate efficacy underlying mechanisms human placental derived (hpMSC-Exos) xenotransplantation incremental load training-induced POI. Method: The exercise treadmill training was employed...
Background: This study aimed to explore appropriate automated external defibrillator (AED) deployment strategies for Gamma cities, addressing the gap in research. By comparing coverage of AEDs under different calculation models, we evaluated rationality distribution a city within eastern China and provided suggestions improvement. Methods: observational used two datasets (an AED inventory an OHCA registry) calculate average distance between out-of-hospital cardiac arrest (OHCA) cases nearest...
Objective: To analyze the mental health and erectile function status of men using sperm donor during pregnancy after ICSI failure in severe oligoasthenospermia to provide reference for clinical implementation more targeted psychological intervention nursing this group. Methods: A total 410 sterile who received assisted treatment our hospital from December 2020 2022 met inclusion exclusion criteria were collected as study subjects. Among them, 68 patients with used Sixty-eight continued...
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system primarily mediated by CD4
Food allergy is a significant public health concern globally. Certain probiotics have been found to enhance food by regulating immune-microbe interactions in animal models and patients. However, the effects of <i>Bifidobacterium lactis</i> Probio-M8 on not thoroughly investigated. The present study examined anti-allergic properties Probio-M8, particularly relation immune response gut microbiota composition. Results demonstrate that oral administration effectively mitigated symptoms triggered...
Patients with end-stage renal disease (ESRD) especially those undergoing dialysis have a high prevalence of hyperkalemia, which must be detected and treated immediately. But the initial symptoms hyperkalemia are insidious, traditional laboratory serum potassium concentration testing takes time. Therefore, rapid real-time measurement is urgently needed. In this study, different machine learning methods were used to make predictions degrees by analyzing ECG.A total 1024 datasets ECG...
Irritable bowel syndrome (IBS) is characterized by visceral pain, impaired intestinal barrier and a disorder of the microbiota. DXL-A-24 has analgesic anti-inflammatory effects inhibiting neuropeptides inflammatory factors. In this study, we used chronic unpredictable mild stress (CUMS) induced IBS model, to assess action on hypersensitivity, function Visceral sensation was assessed colorectal distension in model IBS. The expressions substance P (SP) calcitonin gene-related peptide (CGRP)...
Robotic-assisted thoracoscopic surgery (RATS) and video-assisted (VATS) are new modes for the surgical treatment of mediastinal tumors. The differences in perioperative efficacy safety among RATS, VATS, conventional open (COS) a major concern surgeons. Most previous studies have not paid sufficient attention to roof This study comprehensively analyzed COS
The 2017 high blood pressure (BP) clinical practice guideline reported by the American College of Cardiology/American Heart Association put forward new categories BP. This study aimed to assess applicability in a nondialysis chronic kidney disease (CKD) population.This is nationwide, multicenter, cross-sectional with large sample. A total 8927 CKD patients 61 tertiary hospitals all 31 provinces, municipalities and autonomous regions China (except Hong Kong, Macao Taiwan) were analyzed. BP...
R-CHOP chemotherapy has been established as the first-line standard treatment for elderly patients diagnosed with diffuse large B-cell lymphoma. However, an increased risk of Pneumocystis jirovecii pneumonia in lymphoma after rituximab-based reported. We describe a case who developed intermittent cough, fever and shortness breath five cycles A rapid deterioration patient’s respiratory condition prompted us to adopt aggressive anti- strategy that combined conventional...