A5037210063- Genetic Mapping and Diversity in Plants and Animals
- Diabetes and associated disorders
- Diabetes Management and Research
- Pancreatic function and diabetes
- Gestational Diabetes Research and Management
- Genetics and Plant Breeding
- Genetic and phenotypic traits in livestock
- Plant Stress Responses and Tolerance
- Birth, Development, and Health
- Rice Cultivation and Yield Improvement
- Agriculture, Soil, Plant Science
- Photosynthetic Processes and Mechanisms
- Wheat and Barley Genetics and Pathology
- Adolescent and Pediatric Healthcare
- Biofuel production and bioconversion
- Gut microbiota and health
- Plant Gene Expression Analysis
- Reproductive Physiology in Livestock
- Plant nutrient uptake and metabolism
- Plant Micronutrient Interactions and Effects
- Horticultural and Viticultural Research
- Fermentation and Sensory Analysis
- Maternal Mental Health During Pregnancy and Postpartum
- GABA and Rice Research
- Social Media in Health Education
The University of Adelaide
2011-2025
University of Dundee
2013-2023
James Hutton Institute
2013-2023
Migration Institute of Australia
2021
Australian Wine Research Institute
2019-2020
King Abdullah University of Science and Technology
2016
Women's and Children's Health Network
2010
Women's and Children's Hospital
2010
Imperial College London
1992
University of Leeds
1985
OBJECTIVE Gestational diabetes mellitus (GDM) may cause obesity in the offspring. The objective was to assess effect of treatment for mild GDM on BMI 4- 5-year-old children. RESEARCH DESIGN AND METHODS Participants were 199 mothers who participated a randomized controlled trial during pregnancy and their Trained nurses measured height weight children at preschool visits state-wide surveillance program state South Australia. main outcome measure age- sex-specific Z score based standards...
Abstract High-throughput phenotyping produces multiple measurements over time, which require new methods of analyses that are flexible in their quantification plant growth and transpiration, yet computationally economic. Here we develop such apply this to a rice population genotyped with 700k SNP high-density array. Two diversity panels, indica aus , containing total 553 genotypes, phenotyped waterlogged conditions. Using cubic smoothing splines estimate identify four time intervals...
Effects of several inoculation protocols using Saccharomyces cerevisiae strain AWRI 838 (an isolate Lalvin EC11 18) and Candida stellata 1159 (CBS 2649) upon the aroma properties chemical composition Chardonnay wine were determined. An increase in concentration glycerol acetic acid was observed when fermentation performed with C. 1159, which did not progress to dryness. Sensory descriptive analysis showed a substantial difference between wines produced by monocultures two yeast species. The...
Producing sufficient food for nine billion people by 2050 will be constrained soil salinity, especially in irrigated systems. To improve crop yield, greater understanding of the genetic control traits contributing to salinity tolerance field is needed. Here, we exploit natural variation exotic germplasm taking a genome-wide association approach new nested mapping population barley called HEB-25. The large (1,336 genotypes) allowed cross-validation loci, which, along with two years phenotypic...
Summary Barley ( H ordeum vulgare ) is a crop of global significance. However, third the genes barley are largely inaccessible to conventional breeding programmes as crossovers localised ends chromosomes. This work examines whether can be shifted more proximal regions simply by elevating growth temperature. We utilised genome‐wide marker set for linkage analysis combined with cytological mapping crossover events examine recombination landscape plants grown at different temperatures. found...
This cohort study examines whether there is a temporal association between SARS-CoV-2 infection and the development of islet autoimmunity among Australian children with first-degree relative type 1 diabetes.
This paper presents the results from an investigation to assess development of a Riesling and wooded Chardonnay wine over five years following imposition several treatments at bottling. The wines were bottled under screw cap closure, two different natural corks, synthetic closure in glass ampoule. In addition, effect storage orientation was investigated. stored controlled temperature humidity conditions. Various analyses carried out on replicate bottles each treatment, including sulfur...
Abstract Genomic selection in crop breeding introduces modeling challenges not found animal studies. These include the need to accommodate replicate plants for each line, consider spatial variation field trials, address line by environment interactions, and capture nonadditive effects. Here, we propose a flexible single-stage genomic approach that resolves these issues. Our linear mixed model incorporates through environment-specific terms, also randomization-based design terms. It considers...
In many cereal crops, meiotic crossovers predominantly occur toward the ends of chromosomes and 30 to 50% genes rarely recombine. This limits exploitation genetic variation by plant breeding. Previous reports demonstrate that chiasma frequency can be manipulated in plants depletion synaptonemal complex protein ZIPPER1 (ZYP1) but conflict as direction change, with fewer chiasmata reported Arabidopsis thaliana more for rice (Oryza sativa). Here, we use RNA interference (RNAi) reduce amount...
(1,3;1,4)-β-Glucan is an important component of the cell walls barley grain as it affects processability during production alcoholic beverages and has significant human health benefits when consumed above recommended threshold levels. This leads to diametrically opposed quality requirements for different applications low levels (1,3;1,4)-β-glucan are required brewing distilling high positive impacts on health. We quantified content in a collection 399 2-row Spring-type, 204 Winter-type elite...
Caffeic acid O-methyltransferase (COMT), the lignin biosynthesis gene modified in many brown-midrib high-digestibility mutants of maize and sorghum, was targeted for downregulation small grain temperate cereal, barley (Hordeum vulgare), to improve straw properties. Phylogenetic expression analyses identified COMT orthologue(s) expressed stems, defining a larger family than brachypodium or rice with three genes lignifying tissues. RNAi significantly reduced stem protein enzyme activity,...
Salt stress decreases plant growth prior to significant ion accumulation in the shoot. However, processes underlying this rapid reduction are still unknown. To understand changes salt responses through time and at multiple physiological levels, examining different within a single set-up is required. Recent advances phenotyping has allowed image-based estimation of growth, morphology, colour photosynthetic activity. In study, we examined stress-induced 191 Arabidopsis accessions from 1 h 7...
Continuous glucose monitoring (CGM) can detect early dysglycemia in older children and adults with presymptomatic type 1 diabetes (T1D) predict risk of progression to clinical onset. However, CGM data for very young at greatest disease are lacking. This study aimed investigate the use measured being longitudinally observed Australian Environmental Determinants Islet Autoimmunity (ENDIA) from birth age 10 years.
To evaluate maternal and neonatal outcomes associated with birth at term by week of gestational age also onset labor.Cohort study.A state-wide perinatal outcome database.28,626 women spontaneous labor, induction labor for recognized indications non-recognized indications.Cohort study utilizing a validated dataset comparing type using log binomial model.Cesarean section, assisted vaginal birth, important measures morbidity.Induction was significantly increased risk range outcomes, including...
The gut microbiome changes in response to a range of environmental conditions, life events and disease states. Pregnancy is natural event that involves major physiological adaptation yet studies the pregnancy are limited their findings inconsistent. with type 1 diabetes (T1D) associated increased maternal fetal risks but this context has not been characterized. By whole metagenome sequencing (WMS), we defined taxonomic composition function bacterial across 70 pregnancies, 36 women T1D.Women...
Barley is a major cereal crop for temperate climates, and diploid genetic model polyploid wheat. Cereal straw biomass an attractive source of feedstock green technologies but lignin, key determinant recalcitrance, complicates bio-conversion processes. However, manipulating lignin content to improve the conversion process could negatively affect agronomic traits. An alternative approach manipulate composition which influences physical chemical properties straw. This study validates function...
This paper presents the results from an investigation to assess development of a Riesling and wooded Chardonnay wine over five years. The wines were bottled either with or without added ascorbic acid stored under controlled temperature humidity conditions. Ascorbic addition at bottling had little effect on aroma flavour when in this study been bottle for 6 months less. For both wines, storage times 3 years more, resulted no difference less oxidised and/or more fresh fruity aromas, even if...
This study was conducted to investigate the effects of paternal heat stress on development in vitro preimplantation embryos mouse. Female C57/CBA mice were superovulated using eCG/hCG and mated either an untreated (control) male mouse or one that had been exposed for 24 h ambient temperature 36 +/- 0.1 degrees C 62 0.4% relative humidity, between 3 42 days previously. Putative zygotes collected from oviducts mice, 25-28 after hCG injection, cultured vitro. Embryo evaluated at 24-h intervals...
Abstract During plant growth, sodium (Na + ) in the soil is transported via xylem from root to shoot. While excess Na toxic most plants, non-toxic concentrations have been shown improve crop yields under certain conditions, such as when K low. We quantified grain across a barley genome-wide association study panel grown non-saline conditions and identified variants of Class 1 HIGH-AFFINITY-POTASSIUM-TRANSPORTER ( HvHKT1;5 )-encoding gene responsible for content variation these conditions. A...
Introduction The Environmental Determinants of Islet Autoimmunity (ENDIA) Study is an ongoing Australian prospective cohort study investigating how modifiable prenatal and early-life exposures drive the development islet autoimmunity type 1 diabetes (T1D) in children. In this profile, we describe cohort’s parental demographics, maternal neonatal outcomes human leukocyte antigen (HLA) genotypes. Research design methods Inclusion criteria were unborn child, or infant aged less than 6 months,...
Summary To optimize shoot growth and structure of cereals, we need to understand the genetic components controlling initiation elongation. While measuring total at high throughput using 2D imaging has progressed, recovering 3D small grain cereals a large scale is still challenging. Here, present method for defined individual leaves such as wheat barley, few images. Plant modelling over time was used measure elongation in bi‐parental barley mapping population under low soil salinity. We...