A5040176280- Ophthalmology and Eye Disorders
- Pituitary Gland Disorders and Treatments
- Thyroid Disorders and Treatments
- Glaucoma and retinal disorders
- Bone health and osteoporosis research
- Growth Hormone and Insulin-like Growth Factors
- Management and Organizational Practices
- Electrolyte and hormonal disorders
- Erythrocyte Function and Pathophysiology
- Genetic Syndromes and Imprinting
- Advanced Differential Geometry Research
- Amino Acid Enzymes and Metabolism
Medical University of Warsaw
2018-2024
Therapy with intravenous glucocorticoids (GCs) is associated various side effects, however, the impact on bone remains elusive. Trabecular score (TBS) a diagnostic tool providing information microarchitecture based images obtained from dual-energy X-ray absorptiometry. We investigated influence of methylprednisolone (IVMP) pulse administration TBS in patients moderate-to-severe Graves' orbitopathy (GO).Fifteen GO were treated 12 IVMP pulses (6x0.5g, 6x0.25 g weekly schedule). They received...
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To evaluate the influence of intravenous methylprednisolone (IVMP) pulse administration on bone mineral density (BMD) lumbar spine and femoral neck in patients with moderate-to-severe Graves' orbitopathy (GO).Thirty-five GO euthyreosis were treated 12 IVMP pulses (6 × 0.5 g, 6 0.25 g a weekly schedule). Supplementation 1.0 calcium 800 IU vitamin D was initiated all before beginning therapy. BMD (L1-L4) assessed at baseline after last using dual-energy X-ray absorptiometry. determine...
Background: Dysthyroid optic neuropathy (DON) is a sight-threatening complication of Graves’ orbitopathy (GO). Treatment DON consists the urgent administration intravenous methylprednisolone (ivMP) in very high doses followed by orbital decompression if response poor or absent. It advised to continue therapy with pulses ivMP weekly schedule. The purpose this study was evaluate impact additional treatment 12-week protocol on visual acuity (VA), color vision, clinical activity score (CAS) and...
Background: Treatment with glucocorticoids (GCs) is associated side effects. In contrast to the well-known negative impact on bone tissue exerted by oral GCs, few data are available regarding intravenous GCs. We investigated influence of methylprednisolone (IVMP) turnover markers (BTM): amino-terminal propeptide type I procollagen (P1NP) and C-terminal telopeptide collagen (CTX), calcium metabolism parameters: 1,25-dihydroxyvitamin D (1,25(OH)2D), 25-hydroxyvitamin (25(OH)D), (Ca), phosphate...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Introduction. Dysthyroid optic neuropathy (DON) is a severe complication of Graves’ orbitopathy (GO). Treatment DON should involve immediate administration intravenous methylprednisolone (ivMP) in very high doses. It recommended to include additional 12 pulses ivMP according weekly schedule as further step the treatment process. The purpose this study was evaluate influence 12-week on quality life (QoL) patients. Material and Methods. A retrospective conducted 6 patients (the tests involved...