Ramachandram Badugu

ORCID: 0000-0003-2428-2922
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About
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Research Areas
  • Plasmonic and Surface Plasmon Research
  • Photonic Crystals and Applications
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Photonic and Optical Devices
  • Molecular Sensors and Ion Detection
  • Analytical Chemistry and Sensors
  • Advanced biosensing and bioanalysis techniques
  • Ocular Surface and Contact Lens
  • Luminescence and Fluorescent Materials
  • Electrochemical sensors and biosensors
  • Optical Coatings and Gratings
  • Nanocluster Synthesis and Applications
  • Advanced Fluorescence Microscopy Techniques
  • Quantum Dots Synthesis And Properties
  • Sulfur Compounds in Biology
  • Near-Field Optical Microscopy
  • Advanced Fiber Optic Sensors
  • Advanced Biosensing Techniques and Applications
  • Lipid Membrane Structure and Behavior
  • Advanced Glycation End Products research
  • Molecular Junctions and Nanostructures
  • Orbital Angular Momentum in Optics
  • Surfactants and Colloidal Systems
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Silicone and Siloxane Chemistry

University of Maryland, Baltimore
2012-2023

Fluor (United States)
2004-2018

University of Baltimore
2014-2015

University of Maryland, Baltimore County
2008

Fluorescence Innovations (United States)
2007

Biotechnology Institute
2003-2006

University of Hyderabad
2002-2005

Tohoku University
2002-2004

RIKEN Center for Advanced Photonics
2003

RIKEN
2003

Three water-soluble fluorescent probes have been specifically designed to determine free cyanide concentrations up physiologically lethal levels, >20 microM. The in such a way as afford many notable sensing features, which render them unique with regard signal transduction, photophysical characteristics, and their application physiological determination safeguard. are readily able reversibly bind aqueous dissociation constants around 4 microM3. Subsequent binding modulates the intramolecular...

10.1021/ja044421i article EN Journal of the American Chemical Society 2005-02-16

We described, for the first time, metal-enhanced fluorescence from CdTe nanocrystals spin coated on silver island films (SIFs). show ∼5-fold increase in intensity, 3-fold decrease lifetimes, and reduction blinking SIF surfaces that can be observed by ensemble single-molecule studies. The study also provides further insight heterogeneity enhancement lifetimes of both glass surfaces, which is otherwise not possible to observe using measurements.

10.1021/ja061762i article EN Journal of the American Chemical Society 2006-06-23

ConspectusFluorescence technology pervades all areas of chemical and biological sciences. In recent years, it is being realized that traditional fluorescence can be enriched in many ways by harnessing the power plasmonic or photonic structures have remarkable abilities to mold flow optical energy. Conventional omnidirectional nature, which makes difficult capture entire emission. Suitably designed emission directivity improve collection efficiency desirable for fluorescence-based...

10.1021/acs.accounts.5b00100 article EN Accounts of Chemical Research 2015-07-13

We have tested the feasibility of tear glucose sensing using a daily, disposable contact lens embedded with boronic acid-containing fluorophores as potential alternative to current invasive glucose-monitoring techniques. Our findings show that our approach may, indeed, be suitable for continuous monitoring levels in range 50-500 microM, which track blood are approximately 5-10-fold higher. compare response acid probes solution-based measurements and can conclude both pH polarity within need...

10.1021/ac0303721 article EN Analytical Chemistry 2003-12-30

In the past several years we have demonstrated metal-enhanced fluorescence (MEF) and significant changes in photophysical properties of fluorophores presence metallic nanostructures nanoparticles. MEF is largely dependent on factors, such as chemical nature, size, shape nanostructure, its distance from interrogating fluorophore. Herein, elucidate potential layer-by-layer (LbL) assembly to understand dependence nature sulforhodamine B (SRB) assembled plasmonic nanostructured surfaces [in form...

10.1021/cm071510w article EN Chemistry of Materials 2007-11-01

We described the effect of fluorophore distance from silver island films (SIFs) on metal-enhanced fluorescence (MEF) two newly developed long-chain nitrobenzoxadiazole derivatives (NBD-C16 and NBD-C18). The well-established Langmuir−Blodgett technique is used to deposit fluorophores at defined distances SIFs surface, an inert amphiphilic stearic acid control distance. NBD probes deposited directly surface show highest ∼32-fold, both that were studied a consistent decrease in when increasing...

10.1021/la061058f article EN Langmuir 2006-08-22

Abstract Polymeric fibres with small radii (such as 125 nm) are delicate to handle and should be laid down on a solid substrate obtain practical devices. However, placing these nanofibres commonly used glass substrates prevents them from guiding light. In this study, we numerically experimentally demonstrate that when the nanofibre is placed suitable dielectric multilayer, it supports guided mode, Bloch surface wave (BSW) confined in one dimension. The physical origin of new mode discussed...

10.1038/ncomms14330 article EN cc-by Nature Communications 2017-02-03

Here, we demonstrate a diffraction-free Bloch surface wave sustained on all-dielectric multilayers that does not diffract after being passed through three obstacles or across single mode fiber. It can propagate in straight line for distances longer than 110 μm at wavelength of 633 nm and could be applied as an in-plane optical virtual probe both air aqueous environment. Its ability to used water, its long distance, tolerance multiple make this ideal certain applications areas such the...

10.1021/acsnano.7b02358 article EN ACS Nano 2017-05-15

Chemical synthesized silver nanowires have been proved to be the efficient architecture for Plasmonic waveguides, but high propagation loss prevents their widely applications. Here, we demonstrate that distance of plasmons along Ag NW can extended if was placed on a dielectric multilayer substrate containing photonic band gap, not commonly used glass substrate. The at 630 nm wavelength reach 16 um even is as thin 90 in diameter. Experimental and simulation results further show polarization...

10.1021/acs.nanolett.7b04693 article EN Nano Letters 2018-01-10

Accurate and reliable monitoring of blood glucose is needed for the treatment diabetes, which has many challenges, including lack patient compliance. Measuring tear an alternative to traditional finger-stick tests used track sugar levels, but sensing using tears yet be achieved. We report a methodology possible glucose-sensitive silicone hydrogel (SiHG) contact lenses, primary type lenses available in today's market. Initially, we assessed interpenetrating polymer network, with nearly pure...

10.1117/1.jbo.23.5.057005 article EN Journal of Biomedical Optics 2018-05-17

In recent years, there has been a growing interest in the studies involving interactions of fluorophores with plasmonic nanostructures or nanoparticles. These lead to several favorable effects such as increase fluorescence intensities, increased photostabilities, and reduced excited-state lifetimes that can be exploited improve capabilities present methodologies. this regard, we report use newly developed silver-gold nanocomposite (Ag-Au-NC) structures substrates for metal-enhanced (MEF)....

10.1021/jp212242x article EN The Journal of Physical Chemistry C 2012-02-03

Bloch surface waves (BSWs) on one-dimensional photonic crystals (1DPCs) have been used to beam the fluorescence emission from dye molecules. All dielectric 1DPC displays its low propagating loss, narrow resonance and absence of absorption or quenching. In this paper, back focal plane imaging reveals that in addition BSW mode, a guided mode cavity also exist which all couple with excited The appearance these modes is sensitive wavelength alters beaming effect by 1DPC. Numerical simulations...

10.1088/0957-4484/25/14/145202 article EN Nanotechnology 2014-03-12

The interaction of fluorophores with nearby metallic structures is now an active area research. Dielectric photonic offer some advantages over plasmonic structures, namely small energy losses and less quenching. We describe a dielectric one-dimensional crystal (1DPC), which supports Bloch surface waves (BSWs) from 280 to 440 nm. This BSW structure quartz slide coated alternating layers SiO2 Si3N4. show that this displays BSWs the near-UV fluorophore, 2-aminopurine (2-AP), on top couples...

10.1021/acs.jpcc.6b08086 article EN The Journal of Physical Chemistry C 2016-11-23
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