Yi Zhang

ORCID: 0000-0003-2430-0940
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Research Areas
  • Phytochemical and Pharmacological Studies
  • Botanical Studies and Applications
  • Traditional Chinese Medicine Analysis
  • Medicinal Plants and Bioactive Compounds
  • Identification and Quantification in Food
  • Plant-based Medicinal Research
  • Phytochemicals and Antioxidant Activities
  • PARP inhibition in cancer therapy
  • Medicinal plant effects and applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Berberine and alkaloids research
  • Medicinal Plants and Neuroprotection
  • Food Industry and Aquatic Biology
  • Antibiotics Pharmacokinetics and Efficacy
  • Pharmacological Effects of Natural Compounds
  • Angiogenesis and VEGF in Cancer
  • Plant Gene Expression Analysis
  • Clinical Reasoning and Diagnostic Skills
  • Remote Sensing and Land Use
  • Chromatography in Natural Products
  • Plant biochemistry and biosynthesis
  • Innovations in Medical Education
  • Ginseng Biological Effects and Applications
  • Macrophage Migration Inhibitory Factor
  • Phytochemistry and biological activities of Ficus species

ZheJiang Academy of Agricultural Sciences
2025

Nanjing Agricultural University
2025

Chengdu University of Traditional Chinese Medicine
2012-2024

Zhejiang Chinese Medical University
2022-2024

Tianjin University of Traditional Chinese Medicine
2020-2023

Sichuan Provincial Hospital of Traditional Chinese Medicine
2022

Weatherford College
2022

University of Macau
2009

Sea buckthorn (Hippophaë; Elaeagnaceae) berries are widely consumed in traditional folk medicines, nutraceuticals, and as a source of food. The growing demand sea morphological similarity Hippophaë species leads to confusions, which might cause misidentification plants used natural products. Detailed information comparison the complete set metabolites different critical for their objective identification quality control. Herein, variation among seven subspecies was studied using proton...

10.1038/s41598-017-01722-3 article EN cc-by Scientific Reports 2017-05-02

This study was conducted to establish a stable hypobaric hypoxia brain injury model. SD rats were randomly separated into control and model groups, placed outside or inside of chamber, respectively. Subsequent 24 h anoxic exposure, plasma superoxide dismutase (SOD), malondialdehyde (MDA), glutathione (GSH), oxidized (GSSG) lactate dehydrogenase (LDH) measured using commercial biochemical kits. Hematoxylin‑eosin (H&E), Nissl's terminal deoxynucleotidyl transferase dUTP nick end labeling...

10.3892/mmr.2019.9939 article EN cc-by-nc-nd Molecular Medicine Reports 2019-02-05

The total flavonoids from sea buckthorn (TFSB) exhibit a potent anti‐inflammatory activity; however, the effect of TFSB on respiratory inflammatory disease is not fully known. present study evaluated potential to prevent airway inflammation and underlying mechanism. results showed that remarkably inhibited lipopolysaccharide/cigarette smoke extract (LPS/CSE)‐induced expression IL‐1β, IL‐6, CXCL1, MUC5AC at both mRNA protein levels in HBE16 bronchial epithelial cells. also decreased...

10.1002/ptr.6404 article EN Phytotherapy Research 2019-06-17

Hepatic fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) which mainly secreted activated hepatic stellate cells (HSCs). Lamiophlomis rotata (L. rotata) was recorded to treat jaundice in traditional Tibetan medical system with potential hepatoprotection. However, bioactivities and possible mechanism L. on still largely unknown.To investigate anti-hepatic effects probable action.Herein, total polyphenolic glycosides (TPLR) purified selectivity adsorption...

10.1186/s13020-023-00723-x article EN cc-by Chinese Medicine 2023-02-24

Abstract Angiogenesis plays an important role in a wide range of physiological processes and many diseases are associated with dysregulation angiogenesis. Radix Astragali , commonly used traditional Chinese medicine, is potential candidate for treating such diseases. However, the biological effects on angiogenesis its underlying mechanisms yet to be elucidated fully. This study describes angiogenic extract (RAE) human umbilical vein endothelial cells (HUVEC) vitro . It was shown that RAE...

10.1002/ptr.2479 article EN Phytotherapy Research 2009-03-09

The morphological identification of different Hippophae species (Shaji) was difficult. This study aims to discriminate between medicinal and non-medicinal by DNA barcodes, the ITS2, psbA-trnH, a combination ITS2 psbA-trnH (ITS2 + psbA-trnH).DNA extracted from dried fruit samples. Primer pairs ITS2F/3R for psbAF/trnHR were used PCR amplification. purified products bidirectionally sequenced. Genetic distances calculated according Kimura 2 parameter model phylogenetic tree constructed based on...

10.1186/s13020-015-0062-9 article EN cc-by Chinese Medicine 2015-10-13

Chinese yam (Dioscorea polystachya Turcz.), known for its nutrient-rich underground tubers, is both a food source and traditional medicinal plant. It offers significant nutritional benefits. In 2023, the cultivation of yam, specifically Wencheng Waxy Yam variety, exceeded 400 hectares in County, Zhejiang Province, China, with an annual yield surpassing 9,000 tons (Chen et al. 2024). This crop has become vital industry local farmers mountainous areas. July black leaf spot disease was detected...

10.1094/pdis-10-24-2193-pdn article EN Plant Disease 2025-01-28

Angelica anomala Avé-Lall (Chuanbaizhi in Chinese) is an important medicinal plant which can be used traditional Chinese medicines; however, there are no authentic and universal methods to differentiate this Sichuan famous-region drug of A. from a large number non-famous-region false drugs. It has been demonstrated that DNA barcoding molecular diagnostic method for species identification, uses single standardized fragment. In study, we tested five candidates (matK, ITS, ITS2, rbcL,...

10.3109/19401736.2012.660924 article EN Mitochondrial DNA 2012-03-07

Abstract Background Standardized patient (SP) simulations are well-recognized patterns for practicing clinical skills and interactions. Our previous study showed that a simulation program using occupational SP Traditional Chinese Medicine (OSP-TCMs) was efficient, however, high cost time-intensive nature have limited its use. TCM postgraduates trained as student SPs (SSP-TCMs) present potentially cost-effective alternative. The purpose of this to examine determine whether SSP offered more...

10.1186/s12909-023-04198-0 article EN cc-by BMC Medical Education 2023-04-05

Insulin resistance (IR) is considered as one of the principal pathways type 2 diabetes mellitus pathogenesis and associated with a series abnormal signaling pathways. Tangzhiqing (TZQ) herbal formula well-known antidiabetic traditional Chinese medicine has been used to treat prediabetes for many years in China. We selected 13 natural products representative compounds main active components TZQ investigate interaction these key signal proteins IR using two different docking calculations....

10.1155/2020/1057648 article EN cc-by Evidence-based Complementary and Alternative Medicine 2020-01-01

Objective: To clarify the mechanism of triptolide (TP) in alleviating conditions underlying SLE. Methods: Eight-week-old MRL/lpr mice were randomly divided into a model group (n = 5), low-dose TP (TP-L) and high-dose (TP-H) 5). Mice these groups gavaged with normal saline, solution, solution for 8 weeks, respectively. The expression levels anti-dsDNA, IgG, IgM, IgA, C3, C4, CREA, BUN, ALT, AST, ALB, ALP indexes serum detected. proportion CD19+CD138+B220- cells spleen pathological changes...

10.3389/fphar.2022.952775 article EN cc-by Frontiers in Pharmacology 2022-09-23

The aim was to evaluate the protective effects of total flavones Elaeagnus rhamnoides (L.) A. Nelson (TFE) against vascular endothelial injury in blood stasis model rats and explore potential mechanisms preliminarily. rat with induced by subcutaneous injection adrenaline combined ice-water bath. Whole viscosity (WBV), histological examination, prothrombin time (PT), activated partial thromboplastin (APTT), fibrinogen (FIB) were measured. Meanwhile, levels Thromboxane B2 (TXB 2 ), 6-keto-PGF...

10.1155/2017/8142562 article EN Evidence-based Complementary and Alternative Medicine 2017-01-01

Some Western medicine schools in China established standardized patient (SP) programs for medical education. However, SP are rarely applied to the education of traditional Chinese (TCM). In this study, we evaluated effectiveness using (SP-TCM) improve clinical competency among TCM students.This study was a prospective, 2-group, parallel-training randomized trial over course 5 years. Data were collected from September 2016 December 2020. Participants each year randomly allocated into...

10.1016/j.imr.2021.100804 article EN cc-by-nc-nd Integrative Medicine Research 2021-11-10
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