A5053125793- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- HIV-related health complications and treatments
- Cardiovascular Disease and Adiposity
- COVID-19 Clinical Research Studies
- Adolescent Sexual and Reproductive Health
- Healthcare during COVID-19 Pandemic
- Cardiovascular Health and Disease Prevention
- HIV, Drug Use, Sexual Risk
- Insect Pest Control Strategies
- Atherosclerosis and Cardiovascular Diseases
- Indigenous Health and Education
- Vitamin D Research Studies
- Sex work and related issues
- SARS-CoV-2 and COVID-19 Research
- Syphilis Diagnosis and Treatment
- Plant Virus Research Studies
- Animal Law and Welfare
- SARS-CoV-2 detection and testing
- Virology and Viral Diseases
- HIV/AIDS Impact and Responses
- Mosquito-borne diseases and control
- T-cell and Retrovirus Studies
- Vitamin C and Antioxidants Research
Universidade Federal de Pernambuco
2013-2024
Universidade Federal Rural do Rio de Janeiro
2024
Instituto de Medicina Integral Professor Fernando Figueira
2021-2024
Hospital das Clínicas da Universidade Federal de Pernambuco
2019-2022
Faculdade Frassinetti do Recife
2022
PharmacoGenetics (China)
2022
Bioinformatics Institute
2021
Hospital de Clínicas de Porto Alegre
2020
Nonadherence to antiretroviral therapy (ART) may lead viral replication and development of resistance.To identify the factors associated with nonadherence ART among people living human immunodeficiency virus (HIV)/acquired syndrome (AIDS) (PLWHA).Cross-sectional study in a tertiary-level hospital northeastern Brazil.Intake less than 90% drugs prescribed last week prior interview was defined as nonadherence. Intake evaluated using questionnaire. Descriptive multivariate analyses were...
Diverse human immunodeficiency virus 1 (HIV-1) subtypes and circulating recombinant forms are found in Brazil. The majority of HIV-1 molecular epidemiological studies Brazil have been conducted the southern south-eastern regions country, although several recent north-eastern region addressed this issue. objective study was to molecularly characterize Pernambuco, Brazil.A total 64 samples were collected from 2002 2003, another 103 2007 2009. protease partial reverse transcriptase...
Background HIV-1 diversity causes important differences in the virus' biological properties and their interactions with hosts, such as cell tropism, responses to antiretroviral therapy, drug-resistance, disease progression. Objectives We evaluated interrelationship of phylogenetic inference epidemiological laboratory data for isolates circulating Pernambuco, Northeast Region—Brazil. Study design A total 168 pol sequences were analysed, 64 obtained from 2002–2003, 104, 2007–2009....
The HIV-1 epidemic in Brazil has been growing northeast and north regions, particularly an increase AIDS cases among the younger male population observed. This study aims to characterize genetic diversity evaluate its antiretroviral resistance profile individuals presenting virological failure state of Maranhão—Brazil. pol gene sequences from 633 patients on therapy were obtained Department Surveillance, Prevention Control Sexually Transmitted Infections, HIV/AIDS Viral Hepatitis Brazilian...
The efficacy of direct-acting antivirals (DAAs) in the treatment chronic hepatitis C (CHC) liver transplant recipients is poorly understood, and several factors, including immunosuppression, drug interactions, elevated viraemia, intolerance to ribavirin (RBV), can reduce cure rates. We conducted a real-life study on with CHC treated combination sofosbuvir (SOF) daclatasvir (DCV) or simeprevir (SIM), without RBV, followed-up for 12 24 weeks. effectiveness was assessed by determining sustained...
We evaluate the genetic characterization of 132 HIV-1 pol sequences from children and adolescents undergoing antiretroviral therapy in Northeast Brazil. Phylogenetic recombination analyses were performed using maximum likelihood method SeaView version 4 SIMPLOT software. Most individuals harbored B (84.8%) BF recombinants (9.8%), although other non-B subtypes detected: C (1.5%), F (2.4%), BC (1.5%). Antiretroviral resistance was 47% (95% confidence interval [CI]: 38.7%-55.4%). Non-nucleoside...
People living with HIV are at increased risk of cardiovascular disease and carotid thickness, due to the inflammation caused by virus, antiretroviral therapy, other factors. However, few studies have observed occurrence diseases thickness in HIV-positive population low undetectable viral load.To evaluate association between levels inflammatory markers people HIV, under therapy risk.To determine both groups (HIV infected non-infected individuals), Framingham Risk Score was used. Inflammatory...
Conditions related to the acquired immune deficiency syndrome (AIDS) are still a significant cause of morbidity and mortality among people living with HIV (PLHIV). Longer survival in this population were reported increase risk developing noncommunicable chronic diseases (NCDs). This study aimed estimate causes death according age group sex PLHIV monitored at two referral centers Northeastern Brazil. is prospective, retrospective cohort records from 2007 2018, based on database that registers...
Objetivo: Delimitar a função dos profissionais de enfermagem em relação às suas respon-sabilidades no âmbito indígena. Métodos: Este é um estudo descritivo e exploratório, que metodologia adotada foi Revisão Integrativa Literatura, realizada bases dados bibliotecas virtuais, como Scielo (Scientific Electronic Library Online), Lilacs (Literatura Latino-Americana do Caribe Ciências Saúde), BVS (Biblioteca Virtual Medline (Sistema Online Análise Recuperação Literatura Médica) Pubmed Nacional...
Objectives The purpose of this case-control study was to verify the association between single nucleotide polymorphisms (SNPs) in genes encoding drug transporters related tenofovir disoproxil fumarate (TDF) and proximal renal tubular dysfunction (PRTD), PRTD clinical characteristics. Methods ‘cases’ met diagnostic criteria for PRTD, determined by presence two or more following abnormalities: non-diabetic glycosuria, metabolic acidosis, increased uric acid phosphorus excretion, decreased...
<h3>Background</h3> The highly active anti-retroviral therapy (HAART) has increased survival of patients with HIV/AIDS. However, some individuals may present therapeutic failure due to a variety factors, including transmitted antiretroviral resistance. Thus, the objective study was investigate frequency primary resistance and recent infection among HIV-1 seropositive at five Voluntary Counseling Testing Centers (VCT) Metropolitan Region Recife in Northeast Brazil. <h3>Methods</h3> For RNA...
<h3>Background</h3> Estimates of incidence and prevalence are important tools for the investigation regional trends HIV epidemic. Currently, use immunoassays epidemiology is referred by RITA (Recent Infection Testing Algorithm). This study aimed to determine HIV-1 in two Voluntary Counseling (VCT) Centers, Metropolitan Region Recife - Northeast Brazil, period from 2008 2009 <h3>Methods</h3> Demographics behavioural data were obtained 245 individuals diagnosed as HIV-positive among 19,451...
Objectives: To evaluate the frequency of HIV serodiscordants couples and their seronegative partners who were candidates for pre-exposure prophylaxis (PrPE), knowledge about behavioural measures to reduce virus transmission. Methods: The research was performed in Northeastern Brazil, from February 2016 March 2017. Ninety HIV-positive individuals (Index) HIV-serodiscordant (n = 17) submitted epidemiological, clinical, laboratory questionnaires, rapid tests syphilis, hepatitis B C. Results:...