A5006209499- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- HER2/EGFR in Cancer Research
- Breast Implant and Reconstruction
- Advanced Breast Cancer Therapies
- COVID-19 and healthcare impacts
- Cancer Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer Cells and Metastasis
- Cancer Risks and Factors
- Trauma and Emergency Care Studies
- Cuban History and Society
- Reconstructive Surgery and Microvascular Techniques
- Neurological disorders and treatments
- Lung Cancer Treatments and Mutations
- MRI in cancer diagnosis
- Cancer Genomics and Diagnostics
- Estrogen and related hormone effects
- BRCA gene mutations in cancer
- Urticaria and Related Conditions
- Medical Imaging Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Systemic Sclerosis and Related Diseases
- Radiomics and Machine Learning in Medical Imaging
Hospital Universitario La Paz
2016-2025
Universidad Autónoma de Madrid
2017-2025
Hospital La Paz Institute for Health Research
2021-2024
University of the Basque Country
2019-2022
Mercy St. Vincent Medical Center
2005
Mercy Medical Center
2005
Emory University
2005
Instituto Nacional de Salud Pública
2000
Background/Objectives: The EndoPredict® assay has been widely used in recent years to estimate the risk of distant recurrence and absolute chemotherapy benefit for patients with estrogen (ER)-positive/human epidermal growth factor receptor 2 (HER2)-negative breast cancer. However, there are no well-defined criteria selecting who may from test. aim this study was develop a novel nomogram probability obtaining high-risk result clinical practice. Methods: cohort comprised 348 cases...
Marker placement in a pathological node improves extirpation rates breast cancer cases with limited axillary involvement. Our goal was to assess current indications for seed marked lymph dissection (SMALND). We conducted descriptive observational study including 93 patients cN1 between January 2019 and December 2023. Seed performed under ultrasound guidance days before the procedure. Intraoperative detection achieved using probe, resection confirmed radiologically. The primary indication...
<title>Abstract</title> <bold>Background: </bold>Workplace discrimination is a recognised social determinant of mental health. However, evidence regarding its impact in highly masculinised and demanding industries, such as mining, remains limited, particularly Latin America. This study aimed to estimate the association between perceived observed workplace depressive symptoms among mining workers Chile, evaluate mediating role psychological distress. <bold>Methods: </bold>A cross-sectional...
Purpose: Marker placement in a pathological node improves extirpation rates breast cancer cases with limited axillary involvement. Our goal was to assess the current indications for seed-marked lymph dissection (SMALND). Methods: We conducted descriptive observational study, including 93 patients cN1 treated between January 2019 and December 2023. Seed performed under ultrasound guidance, days before procedure. Intraoperative detection achieved using probe, resection confirmed...
The epidemiological emergency caused by has changed priorities in breast cancer management.In those places where the pandemic had greatest effect, it is of paramount importance for most patients to be at home, reducing or postponing their attendance clinics, as well avoiding surgeries.In this scenario, neoadjuvant endocrine treatment could an appropriate alternative hormone receptor positive (luminal-like tumours) order minimise hospital admissions and delay elective surgeries.Accordingly,...
The purpose of this article is to discuss the feasibility using computer-enhanced instrumentation improve visualization and therefore patient safety during transaxillary first rib resection. From November 1998 July 2005, 105 patients who had failed conservative treatment underwent 131 procedures for thoracic outlet decompression. Eighty-nine endoscopic resections were completed Aesop/Hermes integrated voice control (Computer Motion, Goleta, CA). Since February 2003, dissection in 42 was...
Background: Breast cancer treatments involve tumorectomy or mastectomy. Over the past few decades, authors have been offering direct breast reconstruction with anatomical, gel-cohesive, extra-projection prostheses. This study aimed to demonstrate that directly prostheses in a subpectoral pocket is feasible and safe. Methods: From 2002 through 2008, 400 reconstructions were performed at single center. The prosthesis was covered by muscle its upper two-thirds using skin from mastectomy lower...
Purpose: Neoadjuvant endocrine treatment (NET) has become a useful tool for the downstaging of luminal-like breast cancers in postmenopausal patients. It enables us to increase breast- conserving surgery (BCS) rates, provides an opportunity assess vivo NET effectiveness, and allows study any biological changes that may act as valid biomarkers. The purpose this was evaluate safety effectiveness NET, role Ki67 proliferation rate indicator responsiveness. Methods: From 2016 2020,...
Essential tremor (ET) is the most common movement disorder. In fact, its prevalence about 20 times higher than that of Parkinson's disease. addition, studies have shown a high percentage cases, between 50 and 70%, are estimated to be genetic origin. The gold standard test for diagnosis, monitoring differentiate both pathologies based on drawing Archimedes' spiral. Our major challenge develop simplest system able correctly classify spirals, therefore we will exclusively use information x y...
To compare the concordance in risk classification between EndoPredict and MammaPrint scores obtained for same cancer samples on 40 estrogen-receptor positive/HER2-negative breast carcinomas.Formalin-fixed, paraffin-embedded invasive carcinoma tissues that were previously analyzed with as part of routine care patients, classified high-risk (20 patients) low-risk patients), selected to be by assay, a second generation gene expression test combines 8 genes (EP score) two clinicopathological...
The aim of this study is to describe our initial experience using magnetic seeds (Magseed®) guide breast-conserving surgery in non-palpable breast lesions and compare the use seed with wires terms clinical pathological characteristics. We performed a retrospective including all surgeries for under 16 mm from June 2018 May 2021. compared guided those wires, analyzing tumor patient characteristics, surgical time, results specimens. Data 225 cases were collected, 149 by 76 wires. lesion was...
Abstract Background : Breast cancer remains the most commonly diagnosed in women. Breast-conserving surgery (BCS) is standard approach for small low-risk tumors. If efficacy of cryoablation demonstrated, it could provide a minimally invasive alternative to surgery. Purpose To determine success ultrasound-guided achieving absence Residual Invasive Cancer (RIC) patients with ER+/HER2- tumors ≤ 2cm and sonographically negative axillary nodes. Materials Methods This prospective study was carried...
Abstract Background Pregnancy-associated breast cancer (PABC) is a rare entity whose prognosis has previously been studied and subject to controversy. Methods Survival of patients with PABC diagnosed between 2009 2021 during pregnancy or until 1 year after childbirth was compared non-pregnant from the same period at La Paz University Hospital. Cox proportional hazards regression used compare disease-free (DFS) overall (OS) survival groups, adjusting for grade pathologic stage. Results Among...
Recent prospective studies support the feasibility of performing sentinel lymph node biopsy following neoadjuvant chemotherapy in initially fine-needle aspiration cytology or ultrasound-guided biopsy-proven node-positive breast cancer. The main aid is to identify preoperative features that help us predict a complete axillary response these patients and thus select candidates for post-neoadjuvant avoid unnecessary lymphadenectomy.A retrospective observational study with total 150 patients,...
Essential tremor (ET) is a highly prevalent neurological disorder characterized by action-induced tremors involving the hand, voice, head, and/or face. Importantly, hand present in nearly all forms of ET, resulting impaired fine motor skills and diminished quality life. To advance early diagnostic approaches for automated handwriting tasks magnetic resonance imaging (MRI) offer an opportunity to develop essential clinical biomarkers. In this study, we novel approach diagnosis monitoring ET...
Abstract The increasing capacity of today’s technology represents great advances in diagnosing diseases using standard procedures supported by computer science. Deep learning techniques are able to extract the characteristics temporal signals study their patterns and diagnose such as essential tremor. However, these require a large amount data train neural network achieve good results, more has, accurate final model implemented. In this work we propose use augmentation technique improve...
Abstract Background A prognostic model based on the results of molecular analysis sentinel lymph nodes (SLN) is needed to replace information that staging entire axilla provided. The aim study conduct an external validation a previously developed for prediction 5-year DFS in group breast cancer patients had undergone SLN biopsy assessed by One Step Nucleic Acid Amplification (OSNA) method. Methods We collected retrospective data 889 with cancer, who not received systemic treatment before...
<b><i>Aims:</i></b> Breast cancer is the most frequently diagnosed among women. Up to 50% of breast cases occur in patients over age 65 years. Hormonal therapy as a single alternative treatment has been used this population. The aim study was analyze oncological outcomes who received hormonal alone primary treatment. <b><i>Methods:</i></b> We retrospectively reviewed our database find all with from 2006 2011 were treated only at center....