A5048399990- Pituitary Gland Disorders and Treatments
- Hormonal Regulation and Hypertension
- Adrenal Hormones and Disorders
- Adrenal and Paraganglionic Tumors
- Diabetes and associated disorders
- Cancer, Hypoxia, and Metabolism
- Sexual Differentiation and Disorders
- Growth Hormone and Insulin-like Growth Factors
- Electrolyte and hormonal disorders
- Neurological and metabolic disorders
- Hormonal and reproductive studies
- Respiratory Support and Mechanisms
- Diet and metabolism studies
- Vasculitis and related conditions
- Blood disorders and treatments
- Anesthesia and Neurotoxicity Research
- Renal Transplantation Outcomes and Treatments
- Alcoholism and Thiamine Deficiency
- Transplantation: Methods and Outcomes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Clinical practice guidelines implementation
- Autoimmune Neurological Disorders and Treatments
- Sepsis Diagnosis and Treatment
- Infectious Encephalopathies and Encephalitis
- Myasthenia Gravis and Thymoma
Beaumont Hospital
2019-2025
Royal College of Surgeons in Ireland
2022-2025
Mater Misericordiae University Hospital
2018
University Hospital of Wales
2000
Summary We describe a case of 42-year-old gentleman, 5 years post-transsphenoidal surgery (TSS) for pituitary-dependent Cushing’s disease, initially presenting with malignant hypertension. Despite an initial improvement in his blood pressure post-TSS, he was found to be persistently hypertensive on follow-up despite no clinical or biochemical evidence recurrence hypercortisolism. His remained elevated five antihypertensive agents. renin concentration <5 mIU/L (9–103.5) and aldosterone 877...
Long-term glucocorticoid therapy is a key component of immunosuppression for kidney transplant recipients (KTRs), leading to significant cumulative exposure. The aims this study are investigate the prevalence adrenal insufficiency (AI) in KTRs taking prednisolone and develop screening algorithm identify patients at highest risk AI.In cross-sectional cohort study, 67 receiving underwent short synacthen test (SST) measurement exposure.A total 72% (n = 48) participants failed SST. Participants...
Summary This case is the first to describe a patient who experienced concomitant agranulocytosis and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis as an adverse effect of propylthiouracil treatment for Graves’ disease. A 42-year-old female with disease presented emergency department (ED) 2-week history fevers, night sweats, transient lower limb rash, arthralgia, myalgia fatigue. She had been taking 18 months prior presentation. On admission, was evident neutrophil count...
Metabolic encephalopathy is a rare but potentially devastating complication of diabetic ketoacidosis (DKA). This case highlights the dramatic cognitive decline young man due to metabolic complicating DKA. The aims this report are highlight as DKA and explore current research in related brain injury. importance investigation treatment reversible causes also demonstrated.A 35-year-old with background type 1 diabetes mellitus (T1DM) relapsing remitting multiple sclerosis (RRMS) presented...
Abstract Context 11-Oxygenated androgens are a group of adrenal-derived steroids that require peripheral activation. In vitro data highlight putative role for 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) in 11-oxygenated androgen biosynthesis, converting 11β-hydroxyandrostenedione to 11-ketoandrostenedione (11KA4), the direct precursor potent 11-ketotestosterone (11KT). As kidney is major site HSD11B2 expression, we hypothesized patients with chronic disease (CKD) would have reduced...
Encephalopathy associated with autoimmune thyroid disease (EAATD), also known as Hashimoto's encephalopathy, is a rare neurological condition that may occur in patients clinical or sub-clinical disease. The pathogenesis of EAATD has been not clearly elucidated yet. diagnostic criteria include psychiatric symptoms, high levels anti-thyroid antibodies, and exclusion other possible causes encephalopathy. In the large majority cases, respond to immunosuppressant therapies, particular...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
A 22-year-old woman presented with a 12-year history of intensifying paroxysms anxiety, palpitations and recurrent syncope following micturition. The patient was referred to endocrinology upon discovery hypertension. An extended family revealed metastatic phaeochromocytoma paraganglioma in two grand-uncles. Clinical examination hypertension, mean 24-hour ambulatory blood pressure 150/100 mmHg. Supine plasma normetanephrines were markedly elevated raised 3-methoxytyramine, while metanephrines...