A5100447665- CAR-T cell therapy research
- Soft tissue tumor case studies
- Sarcoma Diagnosis and Treatment
- Hip disorders and treatments
- interferon and immune responses
- Marine Biology and Ecology Research
- Adipose Tissue and Metabolism
- Liver Disease and Transplantation
- Multiple Myeloma Research and Treatments
- Orthopaedic implants and arthroplasty
- Immunotherapy and Immune Responses
- Tumors and Oncological Cases
- Drug-Induced Hepatotoxicity and Protection
- Marine and coastal plant biology
- Osteoarthritis Treatment and Mechanisms
- CNS Lymphoma Diagnosis and Treatment
- Cell death mechanisms and regulation
- Phytochemical Studies and Bioactivities
- Migration, Ethnicity, and Economy
- Biosimilars and Bioanalytical Methods
- Radiomics and Machine Learning in Medical Imaging
- Ear and Head Tumors
- Protein Degradation and Inhibitors
- Neurosurgical Procedures and Complications
- Phagocytosis and Immune Regulation
Shandong Marine Resource and Environment Research Institute
2024
Yantai University
2024
Tongji University
2024
Nanyang Medical College
2023-2024
Merchants Chongqing Communications Research and Design Institute
2024
Zhengzhou Central Hospital
2024
Xuzhou Medical College
2024
Xiangya Hospital Central South University
2024
Sanofi (China)
2024
Tianjin University of Technology
2024
The rapid evolution of highly infectious pathogens is a major threat to global public health. In the front line defense against bacteria, fungi, and viruses, antimicrobial peptides (AMPs) are naturally produced by all living organisms offer new possibilities for next-generation antibiotic development. However, low yields difficulties in extraction purification AMPs have hindered their industry scientific research applications. To overcome these barriers, we enabled high expression bomidin,...
Osteoarthritis (OA) is a common long-term complication of developmental dysplasia the hip (DDH) that associated with higher incidence OA. In addition, age onset OA in DDH patients significantly younger than general population. order to investigate early degeneration cartilage, we used rat model was established by straight-leg swaddling position. The hips were isolated from rats and an untreated control group at postnatal weeks 2, 4, 6, 8. Histology proteoglycan levels observed articular...
Prostate cancer is a leading cause of cancer-related mortality in men, highlighting the resistance to current treatments and need for new therapeutic options. PSMA (Prostate-Specific Membrane Antigen) overexpressed prostate tissues compared normal prostatic tissue, rendering it an ideal target therapies, enabling precise delivery agents cells. We evaluated expression 77 Chinese patients using immunohistochemistry (IHC), confirming its high malignant tissues. Due lack clinical activity from T...
Aggressive fibromatosis is a benign tumor with high recurrence rate after surgical resection, particularly in children. Abnormal regulation of β-catenin the presence or absence change genotype has been identified adult sporadic aggressive fibromatosis. However, status expression and mutation remains unclear pediatric patients. The present study was designed to analyze B-catenin analyzed by immunohistochemistry 32 samples from patients withaggressive (21 recurrent cases 11 primary-onset...
This paper presents a roughness analysis of sea surface from visible images by feature measurements texture for the first time. The algorithms presented in this include six use gray level co-occurrence matrix, level-gradient Tamura feature, autocorrelation function, edge frequency and fractional Brownian motion autocorrelation. empirical relationship between wind speeds (or roughness) image are estimated based on extracted data. Our experiments have demonstrated that our methods relation can...
To investigate the effect of endothelial activation and stress index (EASIX) on prognosis patients with angioimmunoblastic T-cell lymphoma (AITL) peripheral lymphoma, not otherwise specified (PTCL-NOS), to compare clinical characteristics in low EASIX high groups.
Pediatric desmoid tumor (PDT) is rare and has a high local recurrence rate. The purpose of the present study was to analyze clinical risk factors in PDT patients.We reviewed data 66 patients from 2004 2015. All underwent macroscopically complete resection, some recurrent tumors were prescribed radiotherapy. Factors such as sex, age at presentation, location, proximity nerves or vasculature analyzed. rate recurrence-free survival analyzed with these factors.All children had extra-abdominal...
The research in this article aims to consider low-carbon factors, through reasonable vehicle allocation and optimization of distribution routes, achieve high satisfaction low total cost, provide an optimized solution for fresh food companies. In article, cargo damage energy carbon emission cost are added the customer constraints based on time quality added, respectively, construct a multi-vehicle cold chain VRP model under perspective. order obtain good initial path method, chromosome is...
Solitary vertebral eosinophilic granuloma is said to be a rare spinal condition in children. ‘Vertebra plana’ considered as the typical radiological feature of involved vertebra; but it could observed only 40% patients. We have studied three pediatric patients with solitary granuloma. Their complaint was pain and/or stiffness back. Two them developed neurological deficits their lower limbs. The diagnosis imaging (plain radiographs, computed tomography scan and magnetic resonance imaging)...
Objective: We aimed to investigate the distribution of [ 68 Ga]Ga-p14-032, a novel PET ligand that binds vascular amyloid, in patients diagnosed clinically with probable cerebral amyloid angiopathy (CAA) compared Alzheimer's disease (AD) and normal controls (NC). Methods: This longitudinal cohort study was composed 10 subjects (three CAA patients, two AD five NC subjects), recruited from clinic China. had history lobar intracerebral hemorrhage (ICH) met modified Boston criteria for CAA. All...
Female-entrepreneurship plays a significantly important role in rural areas of China today. In fact, it is driving force behind inclusive economic development the country as whole. However, notably very little literature out there has focused on impact how widespread usage information technology tools affects mothers entrepreneurship outskirt regions. Here, this paper, authors attempt to explore finer details such an by utilizing data from 2017 Integrated Social Survey; along with IV-Probit...
Aims: Acute liver failure (ALF) is a critical condition caused by various factors, leading to substantial dysfunction. It characterized complex clinical manifestations, rapid progression, and presents significant challenges in diagnosis treatment.Therefore, we investigated the protective effect of Mefunidone (MFD), novel antifibrosis pyridone agent, on ALF mice explored its potential mechanism. Methods: mouse models were established using lipopolysaccharide/D-galactosamine (LPS/D-GalN) or...
Three undescribed isosteroidal alkaloids, przewalskines A-C (1-3), as well seven known alkaloids (4-10) were obtained from Fritillaria przewalskii bulbs. Their structures deduced by extensive HRESIMS, 1D NMR, and 2D NMR analyses, their bioactivities evaluated involving the anti-inflammatory inhibitory potencies on AChE, BChE, Aβ aggregation. Compound 4 revealed potent effect inhibiting aggregation activity with IC
Abstract Colorectal cancer (CRC) is the fourth leading cause of death in world with a global mortality rate over 700,000 annually. While recent advancement diagnosis and prevention has reduced overall number deaths, lack effective durable treatment not significantly improved survival rate. Emerging modalities immunotherapy such as T cell engagers have paved new ways for disease management. However, common challenge to advancing clinic poor target specificity high toxicity associated...
To investigate the effect of progression disease within 24 months (POD24) on overall survival (OS) in patients with mantle cell lymphoma (MCL), and compare clinical characteristics between POD24 non-POD24 patients.
The regenerative braking system is one of the core technologies to reduce energy consumption electric motorcycles and improve their driving range. In this study, performance test principle method for were introduced, including such items as steady-state efficiency transient-state efficiency. tests carried out at different speeds. findings revealed that could reach a maximum 80.45% minimum 40.11%. Additionally, it was observed high speeds higher than low Subsequently, factors affecting...
Desmoid tumor (DT), also known as desmoid-type fibromatosis (DTF) or aggressive (AF) is a rare mesenchymal affecting both children and adults. It non-metastasis but infiltrative, growing with high recurrence rate to even cause serious health problems. This study investigates the biology of desmoid tumors through integrated multi-omics studies.We systematically investigated clinical data 98 extra-abdominal cases in our pediatric institute identified some critical prognostic factors. Moreover,...