- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Urological Disorders and Treatments
- Renal cell carcinoma treatment
- Urinary Bladder and Prostate Research
- Kidney Stones and Urolithiasis Treatments
- Urologic and reproductive health conditions
- Ureteral procedures and complications
- Radiomics and Machine Learning in Medical Imaging
- Renal and Vascular Pathologies
- Diversity and Career in Medicine
- Surgical Simulation and Training
- Pediatric Urology and Nephrology Studies
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Urinary and Genital Oncology Studies
- Global Cancer Incidence and Screening
- Pelvic floor disorders treatments
- Health Systems, Economic Evaluations, Quality of Life
- Inflammatory Biomarkers in Disease Prognosis
- Radiation Dose and Imaging
- Cancer Diagnosis and Treatment
- Renal and related cancers
- Cancer, Lipids, and Metabolism
University of Sharjah
2023-2025
University of California, Irvine
2021-2025
Lankenau Medical Center
2024
King Hussein Cancer Center
2020-2023
University of Pennsylvania
2019-2023
Dubai Hospital
2023
King Hussein Medical Center
2022-2023
GTx (United States)
2022
University of Pittsburgh Medical Center
2019-2022
American University of Beirut Medical Center
2013-2021
Glucagon-like peptide-1 (GLP-1), an incretin hormone renowned for its role in post-meal blood sugar regulation and glucose-dependent insulin secretion, has gained attention as a novel treatment diabetes through GLP-1 receptor agonists (GLP-1-RA). Despite their efficacy, concerns have been raised regarding the potential associations between GLP-1-RA certain malignancies, including medullary thyroid cancer. However, evidence of association with prostate cancer (PCa) remains inconclusive. This...
Several centers have reported their experience with single-port robot-assisted partial nephrectomy (SP-RAPN); however, it is uncertain if utilization of this platform represents an improvement in outcomes compared to multiport (MP-RAPN). To evaluate this, we performed a meta-analysis compare the perioperative, oncological, and functional between SP-RAPN MP-RAPN.
BackgroundWe developed and validated an integrated radiomic-clinicopathologic nomogram (RadClip) for post-surgical biochemical recurrence free survival (bRFS) adverse pathology (AP) prediction in men with prostate cancer (PCa). RadClip was further compared against extant prognostics tools like CAPRA Decipher.MethodsA retrospective study of 198 patients PCa from four institutions who underwent pre-operative 3 Tesla MRI followed by radical prostatectomy, between 2009 2017 a median 35-month...
Inflammation is a critical component of tumorigenesis, and many cancers arise from sites infection, chronic irritation, inflammation. Inflammatory cytokines triggered by tumors alter hematologic components, including neutrophil, lymphocyte, monocyte counts. The neutrophil-to-lymphocyte platelet-to-lymphocyte ratios have been shown to be valuable prognostic markers in various types cancers, bladder cancer. Risk stratification based on clinicopathologic data insufficient support...
BACKGROUND: Prostate cancer (PCa) is the second most frequent cause of cancer-related death in men worldwide. It a heterogeneous disease at molecular and clinical levels which makes its prognosis treatment outcome hard to predict. The epithelial-to-mesenchymal transition (EMT) marks key step invasion malignant progression PCa. We sought assess co-expression epithelial cytokeratin 8 (CK8) mesenchymal vimentin (Vim) locally-advanced PCa as indicators EMT consequently predictors status disease....
Introduction: Current preoperative evaluation methods fail to detect the difference in frailty among patients with same chronological age. Hence, we sought assess ability of a simple 5-item index (5-iFI) score predict surgical outcomes post radical prostatectomy (RP). Methods: The American College Surgeons National Surgical Quality Improvement Program was queried for who underwent RP between 2008 and 2017. 5-iFI calculated by assigning point each following conditions: (1) chronic obstructive...
Purpose: Several case series have demonstrated the safety and feasibility of outpatient robot-assisted radical prostatectomy (RARP) in well-selected patients; however, patient perspective this practice has not been well explored. In study, we explored patients' perspectives on potential barriers benefits RARP. Materials Methods: We developed a multidimensional questionnaire to assess socioeconomic status, presence caretaker at home, preferred transportation emergency room chest pain or...
Clinical trials are valuable evidence for managing urologic malignancies. Early termination of clinical is associated with a waste resources and may substantially affect patient care. We sought to study the rate cancer identify factors trial termination.
Abstract Cerebral and muscular metastases from prostatic adenocarcinoma occur rarely. Patients who develop such metastatic pattern exhibit noticeable symptoms. Herein, we present a 68-year-old man diagnosed with castrate-resistant prostate cancer. The patient received multiple 177 Lu-PSMA cycles. After the last cycle, posttreatment SPECT/CT suggested disease progression uncommon in right temporal brain lobe muscles. 68 Ga-PSMA PET/CT MRI confirmed these findings. Surprisingly, remained...
Introduction:To evaluate the effect of valveless trocar system (VTS) on intra-operative parameters, peri-operative outcomes, and 30-day postoperative complications in patients undergoing robotic-assisted laparoscopic prostatectomy.Methods:A total 200 consecutive Robot-assisted radical prostatectomy by a single surgeon were prospectively evaluated using either (n = 100) or standard trocars 100). Patient demographics, length stay, presence absence nausea vomiting, analog pain score at 0–6...
Percutaneous Nephrolithotomy is the standard surgical procedure used to remove large kidney stones. PCNL procedures have a steep learning curve; physician needs complete between 36-60 procedures, achieve clinical proficiency. Marion Surgical K181 virtual reality simulator, which emulates without compromising well-being of patients. The simulator uses VR headset place user in realistic and immersive operating theatre, haptic force-feedback robots render physical interactions tools patient. has...
Abstract Aim The integration of innovative radio-pharmaceutical agents targeting prostate-specific membrane antigen (PSMA) within nuclear medicine has transformed prostate cancer detection and management. This study aims to investigate the present landscape [177Lu]Lu-PSMA in cancer, elucidating trends, global contributions, scholarly outlets, institutions, thematic concentrations with an aim inform forthcoming research endeavors. Methods We systematically probed Scopus repository for...
The aim of this study is to investigate the effect tumor characteristics and parameters treatment response in predicting biochemical disease-free survival (BFS) for patients with intermediate or high risk prostate cancer treated by combined definitive external beam radiation therapy (EBRT) androgen deprivation (ADT).Between June 1995 January 2015, 375 localized a National Comprehensive Cancer Network (NCCN) categories were EBRT ADT. Median duration blockade was 10 months (range: 3-36...
Abstract Existing tools for post-radical prostatectomy (RP) prostate cancer biochemical recurrence (BCR) prognosis rely on human pathologist-derived parameters such as tumor grade, with the resulting inter-reviewer variability. Genomic companion diagnostic tests Decipher tend to be tissue destructive, expensive, and not routinely available in most centers. We present a non-destructive method automated BCR prognosis, termed "Histotyping", that employs computational image analysis of...
Surgical training programs are pivotal in shaping skilled and compassionate surgeons, with mentors playing a crucial role instilling clinical competence essential attributes. This study aims to describe the characteristics of program directors Endourological Society-accredited fellowship programs.
ABSTRACT What factors influence pelvic floor muscle exercise (PFME) intention and engagement among men post‐radical prostatectomy (RP), how do demographic medical characteristics moderate these relationships? Post‐RP urinary incontinence (UI) affects up to 69% of patients, significantly impacting their quality life. PFME is recommended manage UI, but many patients fail achieve the required frequency intensity, leading suboptimal outcomes. This study seeks identify influencing engagement,...