A5100330240- Fungal Biology and Applications
- Fungal and yeast genetics research
- Mycorrhizal Fungi and Plant Interactions
- Biocrusts and Microbial Ecology
- Food composition and properties
- Microbial Metabolites in Food Biotechnology
- Polysaccharides and Plant Cell Walls
- Virus-based gene therapy research
- Thyroid Cancer Diagnosis and Treatment
- Mitochondrial Function and Pathology
- HIV Research and Treatment
- Parathyroid Disorders and Treatments
- Plant and Biological Electrophysiology Studies
- Genetics, Aging, and Longevity in Model Organisms
- Phytase and its Applications
- Eicosanoids and Hypertension Pharmacology
- Organic Chemistry Cycloaddition Reactions
- Plant tissue culture and regeneration
- Genetic Mapping and Diversity in Plants and Animals
- Magnetic and Electromagnetic Effects
- Wound Healing and Treatments
- Meat and Animal Product Quality
- Slime Mold and Myxomycetes Research
- Phytoestrogen effects and research
- Thyroid and Parathyroid Surgery
Harbin Medical University
2018-2025
First Affiliated Hospital of Harbin Medical University
2018-2025
Henan Institute of Science and Technology
2019-2024
Harbin University of Commerce
2022-2024
Shandong University
2020-2022
Nanjing Agricultural University
2016-2018
Ministry of Agriculture
2017
Union Hospital
2016
Jilin University
2010-2016
Union Hospital
2010-2013
Heat stress (HS) influences the growth and development of organisms. Thus, a comprehensive understanding how organisms sense HS respond to it is required. Ganoderma lucidum, higher basidiomycete with bioactive secondary metabolites, has become potential model system due complete sequencing its genome, transgenic systems, reliable reverse genetic tools. In this study, we found that inhibited mycelium growth, reduced hyphal branching, induced accumulation ganoderic acid biosynthesis heat shock...
Ganoderma lucidum is a medicinal macrofungus that widely used in traditional Chinese medicine. Nonetheless, the scarcity of basic biological studies this organism has hindered further development its commercial value. The pH-responsive transcription factor PacC/Rim101 governs adaptation to environmental pH, and secondary metabolism many fungi. In study, homologue encodes GlPacC was identified higher basidiomycete G. lucidum. composed 807 amino acids contains three typical C2H2 zinc-finger...
The global regulator LaeA plays crucial roles in morphological development and secondary metabolite biosynthesis filamentous fungi. However, the functions of basidiomycetes are less reported. basidiomycete Pleurotus ostreatus is a well-known fungus used both medicine as food that produces polysaccharides cellulolytic enzymes. In this study, we characterized three homologs (PoLaeA1, PoLaeA2, PoLaeA3) P. ostreatus. PoLaeA1 showed different expression patterns than PoLaeA2 PoLaeA3 during...
The alternative oxidase (AOX), which forms a branch of the mitochondrial respiratory electron transport pathway, functions to sustain flux and alleviate reactive oxygen species (ROS) production. In this article, homologous AOX gene was identified in Ganoderma lucidum. coding sequence G. lucidum contains 1038 nucleotides encodes protein 39.48 kDa. RNA interference (RNAi) used study function lucidum, two silenced strains (AOXi6 AOXi21) were obtained, showing significant decreases approximately...
Grain-size is one of the yield components, and first 14 days after pollination (DAP) a crucial stage for wheat grain-size formation. To understand mechanism formation at whole gene expression level to identify candidate genes related grain pattern formation, cDNA libraries from immature grains 5 DAP were constructed. According transcriptome analysis, total 12,555 new 9,358 differentially expressed (DEGs) obtained. In DEGs, 2,876, 3,357 3,125 located on A, B D subgenome respectively. 9,937...
Hypoparathyroidism is a frequent and serious complication of thyroid surgery. Identification preservation the parathyroid glands are key factors in managing hypoparathyroidism. The aim present study was to investigate efficacy rapid intraoperative hormone (rIO-PTH) assay levels through fine needle aspiration (FNA) identifying parathyroids as parameter rIO-PTH FNA frozen section examination were performed on 194 suspected anatomical structures from 50 consecutive patients undergoing...
Summary The cell wall integrity (CWI) signaling activates the transcription factor Swi6 through a MAPK cascade in response to stresses. In this study, we observed two different mRNA variants of swi6 ( GlSwi6A and GlSwi6B ) existed, due alternative splicing. Besides, expression level was higher than that variant. co‐silencing more sensitive stress compared with WT, resulting decrease 78% 76% chitin β‐1,3‐ d ‐glucan content respectively. However, only overexpression decreased sensitivity...
Pleurotus ostreatus is usually cultivated in horticultural facilities that lack environmental control systems and often suffer heat stress (HS). Salicylic acid (SA) recognized as a plant defense-related hormone. Here, SA treatment (200 μM) induced fungal resistance to HS of P. ostreatus, with decreased malondialdehyde (MDA) content HSP expression. Further analysis showed increased the cytosolic trehalose reduced intracellular reactive oxygen species (ROS) level. Moreover, H2O2 could restore...
The association between whole blood viscosity (WBV) and metabolic syndrome (MetS) is still scarcely investigated in the population-based prospective cohort. We aim to explore longitudinal effect of WBV on MetS, verify whether measures can be used as early predictors for MetS. cohort consisted 3,508 adults (2,350 males 1,158 females) who visited health check-up system twice. were measured at four shear rate (200, 50, 10 1 s-1), their values classified into quartiles. Multivariate Cox models...