A5101482202- Nanoplatforms for cancer theranostics
- Gold and Silver Nanoparticles Synthesis and Applications
- Bladder and Urothelial Cancer Treatments
- Advanced Nanomaterials in Catalysis
- Quantum Dots Synthesis And Properties
- Nanoparticles: synthesis and applications
- Graphene and Nanomaterials Applications
- Nanocluster Synthesis and Applications
- Cellular Mechanics and Interactions
- Chalcogenide Semiconductor Thin Films
- Advanced biosensing and bioanalysis techniques
- Photodynamic Therapy Research Studies
- Orthopaedic implants and arthroplasty
- Drug Solubulity and Delivery Systems
- Biosensors and Analytical Detection
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Selenium in Biological Systems
- Carbon and Quantum Dots Applications
- Microplastics and Plastic Pollution
- Total Knee Arthroplasty Outcomes
- Phagocytosis and Immune Regulation
- Orthopedic Infections and Treatments
- Protein Kinase Regulation and GTPase Signaling
- Cell Adhesion Molecules Research
First Affiliated Hospital of Soochow University
2025
Soochow University
2025
National Cheng Kung University
2021-2024
National Pingtung University
2019-2023
Kaohsiung Medical University
2005-2019
National Tsing Hua University
2014
National Hsinchu University of Education
2014
The discovery of different binding receptors to allow rapid and high-sensitivity detection via a noninvasive urine test has become the goal for urothelial carcinoma (UC) diagnosis surveillance. In this study, we developed new screening membrane receptor platform bladder cancer cells by integrating surface-enhanced Raman spectroscopy (SERS) with 4-aminothiophenol (4-ATP)-modified AuAg nanohollows upon NIR laser excitation. have an absorption band at ∼630 nm, slightly off-resonance 785 nm...
The facile and straightforward fabrication of NIR-responsive theranostic materials with high biocompatibility is still an unmet need for nanomedicine applications. Here, we used a natural photosensitizer, iron chlorophyll (Chl/Fe), the J-aggregate template-assisted synthesis Au@Chl/Fe nanorods stability. assembly amount Chl/Fe onto Au surface enabled red–NIR fluorescence monitoring tracking residential tumor lesions. moieties condensed on could change redox balance by photon induction...
Objective The objective of this study was to preliminarily examine the demographic profiles, spectrum pathogenic bacteria, and antibiotic resistance patterns among patients with periprosthetic joint infection (PJI), while also offering deeper insights into microbiological characteristics specifically in diabetic PJI. Methods A retrospective analysis 278 diagnosed PJI from January 2019 December 2024 at our institution performed. Demographic patients, distribution data on were statistically...
Successful synthesis of glyconanoparticles has attracted much attention due to their various biointeractive capabilities, but it is still a challenge understand different single-cell responses exogenous particles among cell populations. Herein, we designed polyaniline-containing galactosylated gold nanoparticles (Au@PGlyco NPs) via in situ polymerization ortho-nitrophenyl-β-galactoside assisted by Au nucleation. The nanogold-carrying polyaniline block produced electromagnetic enhancement...
Here, we utilized inert Cu@poly(styrene-alt-maleic acid) (PSMA) nanoparticles (NPs) as a potential starting material, enabling restrictions on chemical etching and resistance to external toxic surfactant adsorption. Such modulated oxidation–dissolution of Cu allowed preservation the original nano-Cu shape facilitated subsequent deposition Au atoms form AuCu nanoshells with tunable Au/Cu ratio. An increase in concentration fraction at surface nanolayer AuxCu1–x (x = 0.41–0.86) could intensify...
Photodynamic therapy (PDT) is a promising treatment for malignancy. However, the low molecular solubility of photosensitizers (PSs) with accumulation at borderline malignant potential lesions results in tardy and ineffective management recurrent urothelial carcinoma. Herein, we used tannic acid (TNA), green precursor, to reduce HAuCl4 order generate Au@TNA core-shell nanoparticles. The photosensitizer methylene blue (MB) was subsequently adsorbed onto surface nanoparticles, leading...
Recent studies confirm that nanoplastics (NP) cause severe microbial imbalances in various ecosystems, significantly affecting diversity and abundance. Hydroponic systems vital for lettuce production are increasingly threatened by NP contamination irrigation water this issue is gaining global attention. This study investigates species hydroponic altered exposure their impact on growth. While (10
Quantum dots (QDs) are generally toxic as a result of their heavy metal content.
The tumor microenvironment (TME), where immunosuppressive cells such as tumor-associated macrophages (TAMs) proliferate, is the main cause of resistance to antineoplastic treatment for KRAS-driven lung cancer. In this study, we synthesized polymer-based nanoparticles composed a 16 nm-sized Au core and amphiphile, poly-(styrene-alt-maleic acid) (PSMA), via hydrothermal procedure carrying multi-receptor tyrosine kinase inhibitor, sitravatinib (Sit), in new nanodrug (Au@PSMA-Sit). Au@PSMA-Sit...
Objective: The aim of the present study was to design nanocarriers for topical application rivastigmine. Methods: effect cosurfactants, hydrophilic gel and loading amount on permeability rivastigmine through rat skin evaluated. Skin irritation tests stability were performed evaluate utility tested formulations. Results: results showed that microemulsion formation characteristics drug-loaded formulations related many parameters components. When using systems as a vehicle, permeation rate...