- Echinoderm biology and ecology
- Marine Bivalve and Aquaculture Studies
- Aquatic life and conservation
- Marine and coastal plant biology
- Aquaculture Nutrition and Growth
- Coral and Marine Ecosystems Studies
- Ocean Acidification Effects and Responses
- Aquaculture disease management and microbiota
- Marine Biology and Environmental Chemistry
- Metabolomics and Mass Spectrometry Studies
- Seaweed-derived Bioactive Compounds
- Genomics and Phylogenetic Studies
- Marine Sponges and Natural Products
- Invertebrate Immune Response Mechanisms
- Genetic diversity and population structure
- Analytical Chemistry and Chromatography
- Calcium Carbonate Crystallization and Inhibition
- Advanced Chemical Sensor Technologies
- Aquatic Invertebrate Ecology and Behavior
- Mass Spectrometry Techniques and Applications
- Genetic and phenotypic traits in livestock
- Monoclonal and Polyclonal Antibodies Research
- Traditional Chinese Medicine Analysis
- Pharmaceutical and Antibiotic Environmental Impacts
- Cephalopods and Marine Biology
Dalian Ocean University
2016-2025
Ministry of Agriculture and Rural Affairs
2019-2025
Wuhan Botanical Garden
2025
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
2022-2023
University of California, Davis
2020-2023
Huaiyin Institute of Technology
2023
Center for Neurosciences
2023
Wuhan University
2015-2021
Yangzhou University
2014
Dalian University of Technology
2007-2012
Abstract The mammalian brain relies on neurochemistry to fulfill its functions. Yet, the complexity of metabolome and changes during diseases or aging remain poorly understood. Here, we generate a atlas wildtype mouse from 10 anatomical regions spanning adolescence old age. We combine data three assays structurally annotate 1,547 metabolites. Almost all metabolites significantly differ between age groups, but not by sex. A shift in sphingolipid patterns related myelin remodeling is...
Soybean is an important and staple oilseed crop worldwide. Salinity stress has adverse effects on soybean development periods, especially seed germination post-germinative growth. Improving emergence will have positive under salt conditions agricultural production. Here we report that NaCl delays by negatively regulating gibberellin (GA) while positively mediating abscisic acid (ABA) biogenesis, which leads to a decrease in the GA/ABA ratio. This study suggest fluridone (FLUN), ABA...
Echinoderms exhibit several fascinating evolutionary innovations that are rarely seen in the animal kingdom, but how these animals attained such features is not well understood. Here we report sequencing and analysis of genome extensive transcriptomes sea cucumber
Sulfamethoxazole (SMZ) is a frequently detected antibiotic in the environment, and there growing concern about its potential toxic effects on aquatic organisms. sea cucumber (Apostichopus japonicas) benthic invertebrate whose gut acts as primary immune defense serves critical protective barrier. In this study, growth performance, histology, microbiota, metabolomics analyses were performed to investigate response intestine of caused by SMZ stress for 56 d evaluating with different...
Sea urchin, Strongylocentrotus intermedius, transplanted from Japan in 1989, has been widely cultured along the coasts of Liaoning and Shandong Provinces become dominant most economically important maricultured species North China. However, a lesion syndrome symptom S. intermedius broke out frequently these years, showing lethargy activities, blackish peristomial membrane body well lesions, brought about high mortality eventually. Six representative prominent bacterial strains were isolated...
Abstract The genetic structure of populations the sea cucumber Stichopus ( Apostichopus ) japonicus was investigated using 10 microsatellite markers. In all, 152 individuals from five natural were collected Aomori, Japan (JA and JR), Yosu, South Korea (KY), Dalian, China (CD) Vladivostock, Russia (RV). A total 145 alleles found at loci. number per locus ranged 9 PSC03 to 20 SCZ06, with an average 14.5. Average H o e 0.260 (JR) 0.434 (JA) 0.654 (RV) 0.778 respectively. No significant...
Bacterial community plays an important role in keeping the health status of host. A study on characteristics gut bacterial sea cucumber (Apostichopus japonicus) not only helps improve current aquaculture model, but promotes healthy and rapid development industry as well. Therefore, taking pond-cultured (A. studying object, metagenomic 16S rRNA sequencing technology were used this to explore different parts cucumber, well during regeneration after evisceration. The results showed that...
Fatty acid esters of hydroxy fatty acids (FAHFAs) are a family recently discovered lipids with important physiological functions in mammals and plants. However, low detection sensitivity negative ionization mode mass spectrometry makes low-abundance FAHFA challenging to analyze. A 2-dimethylaminoethylamine (DMED) based chemical derivatization strategy was reported improve the MS FAHFAs by labeling positively ionizable tertiary amine group. To facilitate reliable, high-throughput, automatic...
The activity levels of superoxide dismutase (SOD), catalase (CAT), lysozyme (LZM), acid phosphatase (ACP), and alkaline (AKP) can reflect the immune status an organism. may be affected by extreme changes in weather, especially rapid declines temperature. In this study, SOD, CAT, LZM, ACP, AKP Manila clam (Ruditapes philippinarum) were measured for 24 h while seawater temperature rapidly decreased to freezing point from 8 °C, 4 2 °C analyze its immunochemical response decline. results showed...
The contradiction between the rapid development of breeding scale and relatively backward technology is a bottleneck that has restricted Japanese sea cucumber (Apostichopus japonicus) industry. Finding new way to produce seedlings instead traditional model will be highly significant. Previously, we found ecological seedling produced A. japonicus individuals with red body color. Most artificially bred are green, color not yet been reported for japonicus. Therefore, it particularly important...
<title>Abstract</title> Nontargeted peak detection in LC-MS-based metabolomics must become robust and benchmarked. We present MassCube, a Python-based open-source framework for MS data processing that we systematically benchmarked against other algorithms different types of input data. From raw data, peaks are detected by constructing mass traces through signal clustering Gaussian-filter assisted edge detection. Peaks then grouped adduct in-source fragment detection, compounds annotated both...
Rapid and coordinated test growth is crucial for maintaining the normal body shape of Strongylocentrotus intermedius juveniles. In total, 270 S. (1.19 ± 0.01 g) were randomly assigned to 18 floating cages. Three cages sea urchins fed kelp (Saccharina japonica) (control diet) or one five formulated feeds with different carbohydrate-to-lipid ratios (C/L) (1, 2, 4, 8, 16) 90 days. The results suggested that weight gain rate C/L4 was markedly greater than C/L1 C/L16 except kelp, C/L2, C/L8....