A5073417018- Cellular Mechanics and Interactions
- Force Microscopy Techniques and Applications
- Advanced Sensor and Energy Harvesting Materials
- Conducting polymers and applications
- Statistical and numerical algorithms
- 3D Printing in Biomedical Research
- Erythrocyte Function and Pathophysiology
- Collagen: Extraction and Characterization
- Microtubule and mitosis dynamics
- Cardiomyopathy and Myosin Studies
- Advanced Materials and Mechanics
- Phagocytosis and Immune Regulation
- Ferroelectric and Negative Capacitance Devices
- Advanced Memory and Neural Computing
- Image and Object Detection Techniques
- Advanced Antenna and Metasurface Technologies
- Electromagnetic wave absorption materials
- Silk-based biomaterials and applications
- Cellular and Composite Structures
- Copper Interconnects and Reliability
- Hippo pathway signaling and YAP/TAZ
- Advanced Nanomaterials in Catalysis
- Semiconductor materials and devices
- Micro and Nano Robotics
- Quantum Dots Synthesis And Properties
University of Science and Technology of China
2015-2025
Sichuan University
2021-2024
Sun Yat-sen University
2022
Jinan University
2020-2022
State Key Laboratory of Oral Diseases
2021
Southern University of Science and Technology
2021
Xi’an Jiaotong-Liverpool University
2018-2019
University of Liverpool
2018-2019
University of Delaware
2012-2019
Johns Hopkins University
2007-2017
This work illustrates a "soft-toughness" coupling design method to integrate the shear stiffening gel (SSG), natural leather, and nonwoven fabrics (NWF) for preparing leather/MXene/SSG/NWF (LMSN) composite with high anti-impact protecting, piezoresistive sensing, electromagnetic interference (EMI) shielding, human thermal management performance. Owing porous fiber structure of MXene nanosheets can penetrate leather construct stable 3D conductive network; thus both LM LMSN composites exhibit...
Hydrogel-based electronics have received growing attention because of their great flexibility and stretchability. However, the fabrication conductive hydrogels with high stretchability, excellent toughness, outstanding sensitivity, low-temperature stability still remains a challenge. In this study, type consisting double network (DN) structure is synthesized. The dynamically cross-linked chitosan (CS) flexible polyacrylamide doped polyaniline constitute DN through hydrogen bonds between...
Abstract With the booming development of smart wearable devices, flexible multifunctional composites with high sensitivity and well health therapy have evoked great interest for next-generation healthcare electronics. However, weak biocompatibility, low breathability, narrow sensing range greatly hinder sensors. Herein, a porous, conductive MXene/Polydimethylsiloxane/Polydopamine/Polyurethane Sponge (MXene/PDMS/PDA/PU) nanocomposite is developed as promising motion-detecting device good...
Stretchable configuration occupies priority in devising flexible conductors used intelligent electronics and implantable sensors. While most conductive configurations cannot suppress electrical variations against extreme deformation ignore inherent material characteristics. Herein, a spiral hybrid fiber (SHCF) composed of aramid polymeric matrix silver nanowires (AgNWs) coating is fabricated through shaping dipping processes. The homochiral coiled mimicked by plant tendrils not only enables...
Abstract This study presents a novel anti‐fatigue hydrogel electrolyte with slip‐ring structure for next‐generation flexible wearable energy storage systems. Conventional quasi‐solid aqueous zinc‐ion batteries (ZIBs) electrolytes often suffer from mechanical degradation under repeated stress, limiting practical use. To overcome this, dual‐Polyrotaxane (DPR)‐polyacrylic acid (PAA) unique architecture is synthesized, that enhances durability, self‐healing, and adhesion. The interwoven DPR PAA...
Myosin II is a central mechanoenzyme in wide range of cellular morphogenic processes. Its localization dependent not only on signal transduction pathways, but also mechanical stress. We suggest that this stress-dependent distribution the result both force-dependent binding to actin filaments and cooperative interactions between bound myosin heads. By assuming heads induces and/or stabilizes local conformational changes enhances locally, we successfully simulate observed experimentally. In...
Stimuli-responsive nanostructures produced with peptide domains from the extracellular matrix offer great opportunities for imaging and drug delivery. Although individual utility of elastin-like (poly)peptides collagen-like peptides in such applications has been demonstrated, synergistic advantages combining these motifs short conjugates have surprisingly not reported. Here, we introduce conjugation a thermoresponsive (ELP) triple-helix-forming (CLP) to yield ELP–CLP that show remarkable...
Flexible textile displays can be revolutionary for information transmission at any place and time. Typically, are fabricated by traditional rigid electronics that sacrifice mechanical flexibility of devices or flexible do not have an appropriate choice to arbitrarily control single pixels. This work reports on electroluminescent fabric woven ultrastretchable fibers (electroluminescent up 400% stretch, electrode 250% stretch), which exhibit the pixel-based controllable pattern display a...
Over the past few decades, (poly)peptide block copolymers have been widely employed in generating well-defined nanostructures as vehicles for targeted drug delivery applications. We previously reported assembly of thermoresponsive nanoscale vesicles from an elastin-b-collagen-like peptide (ELP-CLP). The were observed to dissociate at elevated temperatures, despite LCST-like behavior tethered ELP domain, which is suggested be triggered by unfolding CLP domain. Here, potential using targeting...
Although various liver chips have been developed using emerging organ-on-a-chip techniques, it remains an enormous challenge to replicate the lobules with self-assembled perfusable hepatic sinusoid networks. Herein we develop a lifelike bionic lobule chip (LLC), on which networks are achieved microflow-guided angiogenesis methodology; additionally, during and after self-assembly, oxygen concentration is regulated mimic physiologically dissolved levels supplied by actual arterioles venules....
Abstract Penetration of immune cells into tumor was believed to be immune-suppressive via cell-in-cell (CIC) mediated death the internalized cells. We unexpectedly found that CIC formation largely led host cells, but not manifesting typical features executed by NK cells; we named this “in-cell killing” which displays efficacy superior canonical way “kiss-killing” from outside. By profiling isogenic CD44 on identified as a negative regulator inhibiting formation. functions antagonize cell...
Temperature-triggered phase separation of recombinant proteins has offered substantial opportunities in the design nanoparticles for a variety applications. Herein, temperature-triggered behavior hydrophilic resilin-like polypeptide (RLP) is described. The transition temperature and sizes RLP-based can be modulated based on variations concentration, salt identity, ionic strength, pH, denaturing agents, as indicated via UV–Vis spectroscopy dynamic light scattering (DLS). irreversible particle...