Hengle Zhang

ORCID: 0000-0003-2664-3445
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Cancer Immunotherapy and Biomarkers
  • Cancer Treatment and Pharmacology
  • Cancer Cells and Metastasis
  • Colorectal Cancer Surgical Treatments
  • Adsorption and biosorption for pollutant removal
  • Nanomaterials for catalytic reactions
  • Graphene research and applications
  • Breast Lesions and Carcinomas
  • Pancreatic and Hepatic Oncology Research
  • Peptidase Inhibition and Analysis
  • Cancer Mechanisms and Therapy
  • Inflammatory mediators and NSAID effects
  • Metastasis and carcinoma case studies
  • Bioactive Compounds and Antitumor Agents
  • Immunotherapy and Immune Responses
  • HER2/EGFR in Cancer Research
  • Gallbladder and Bile Duct Disorders

Hebei Medical University
2022-2023

Cangzhou Central Hospital
2022-2023

Nanjing Tech University
2020

To study the clinical efficacy and quality of life neoadjuvant chemotherapy combined with breast-conserving surgery in treatment triple-negative breast cancer.A retrospective analysis 100 patients cancer was performed from May 2012 to April 2017. The were divided into an observation group a control according different methods, 50 cases each group. received AC-T sequential after surgery, before (neoadjuvant). operation time, postoperative immune function, tumor markers, efficacy,...

10.1155/2022/7847889 article EN Journal of Oncology 2022-05-26

The aim of the study is to evaluate efficacy and prognosis neoadjuvant chemotherapy (NAC) combined with breast-conserving surgery (BCS) in treating triple-negative breast cancer (TNBC) analyze influencing factors predictors efficiency NAC.A retrospective cohort was conducted by dividing patients into two groups according different therapy methods. With BCS as exposure factor, 46 cases were assigned exposed group 80 nonexposed group. We compare difference operation-related indicators,...

10.1155/2023/5431563 article EN cc-by Evidence-based Complementary and Alternative Medicine 2023-01-01

ICOS (Inducible T Cell Costimulator), one of the co-stimulatory B7 superfamily members, was characterized as a receptor for T-cell enhancement. However, role in breast cancer remains largely unknown. The present study systematically investigated expression pattern and its relation to clinical characteristics immunotherapy by integrating multiple cohorts large-scale gene data. This included 2994 tumor samples with transcriptome data matched To make our findings more reliable, we set TCGA...

10.1371/journal.pone.0293469 article EN cc-by PLoS ONE 2023-12-21

To study the clinical effect of Zhengyuan capsule combined with neoadjuvant chemotherapy in treatment triple-negative breast cancer (TNBC).From September 2014 to 2017, 120 TNBC patients who underwent radical mastectomy our hospital were randomly divided into control group (n = 60) and observation 60). The short-term curative effect, incidence toxicity side effects, score quality life compared. Both recurrence metastasis rates also analyzed.The significantly improved objective remission rate...

10.1155/2022/1375724 article EN Evidence-based Complementary and Alternative Medicine 2022-05-23

Objective: To systematically evaluate the clinical efficacy and safety of pertuzumab trastuzumab combined therapy in human epidermal growth factor receptor 2 (HER-2) positive breast cancer through a meta-analysis. Methods: English databases including PubMed, Embase, Cochrane Central Register Controlled Trials, as well Chinese China National Knowledge Infrastructure, Wanfang Database, Biomedical Literature Service System (Sinomed), were searched for randomized controlled trials (RCTs)...

10.53964/jmmo.2023004 article EN Journal of Modern Medical Oncology 2023-04-25
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