A5049743166- Wheat and Barley Genetics and Pathology
- Plant Disease Resistance and Genetics
- Chromosomal and Genetic Variations
- Genetic Mapping and Diversity in Plants and Animals
- Genetics and Plant Breeding
- Plant Pathogens and Resistance
- Yeasts and Rust Fungi Studies
- Bioenergy crop production and management
- Plant Stress Responses and Tolerance
- Plant-Microbe Interactions and Immunity
- Plant Genetic and Mutation Studies
- Crop Yield and Soil Fertility
- Carbon and Quantum Dots Applications
- Plant Micronutrient Interactions and Effects
- Pharmacological Effects of Natural Compounds
- Plant tissue culture and regeneration
- Plant Gene Expression Analysis
- Plant nutrient uptake and metabolism
- Phytase and its Applications
- Selenium in Biological Systems
- Tree Root and Stability Studies
- Heavy Metals in Plants
- Ferroptosis and cancer prognosis
- Plant Molecular Biology Research
- Galectins and Cancer Biology
Sichuan Agricultural University
2016-2025
Jilin University
2025
Affiliated Hospital of Chengde Medical College
2024
Gannan Medical University
2024
Peking University
2023
Hebei Agricultural University
2023
Howard Hughes Medical Institute
2023
University of California, Davis
2023
Shandong Agricultural University
2021
Second Affiliated Hospital of Jilin University
2017
Nascent allohexaploid wheat may represent the initial genetic state of common (Triticum aestivum), which arose as a hybrid between Triticum turgidum (AABB) and Aegilops tauschii (DD) by chromosome doubling outcompeted its parents in growth vigor adaptability. To better understand molecular basis for this success, we performed mRNA small RNA transcriptome analyses nascent following generations, their progenitors, natural cultivar Chinese Spring, with assistance recently published A D genome...
Common oat (Avena sativa) is an important cereal crop serving as a valuable source of forage and human food. Although reference genomes many crops have been generated, such work in has lagged behind, primarily owing to its large, repeat-rich polyploid genome. Here, using Oxford Nanopore ultralong sequencing Hi-C technologies, we generated reference-quality genome assembly hulless common oat, comprising 21 pseudomolecules with total length 10.76 Gb contig N50 75.27 Mb. We also produced...
Abstract Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici ( Pst ), is a global threat to wheat production. Aegilops tauschii , one of the progenitors, carries YrAS2388 locus for resistance on chromosome 4DS. We reveal that encodes typical nucleotide oligomerization domain-like receptor (NLR). The -resistant allele YrAS2388R has duplicated 3’ untranslated regions and characterized alternative splicing in nucleotide-binding domain. Mutation disrupts its synthetic hexaploid...
Summary Pre‐harvest sprouting (PHS), the germination of grain before harvest, is a serious problem resulting in wheat yield and quality losses. Here, we mapped PHS resistance gene PHS‐3D from synthetic hexaploid to 2.4 Mb presence–absence variation (PAV) region found that its effect was attributed pleiotropic Myb10‐D by integrated omics functional analyses. Three haplotypes were detected this PAV among 262 worldwide lines 16 Aegilops tauschii , percentages containing approximately 40% lower...
Leaf rust, caused by Puccinia triticina Eriksson (Pt), is one of the most severe foliar diseases wheat. Breeding for leaf rust resistance a practical and sustainable method to control this devastating disease. Here, we report identification Lr47, broadly effective gene introgressed into wheat from Aegilops speltoides. Lr47 encodes coiled-coil nucleotide-binding leucine-rich repeat protein that both necessary sufficient confer Pt resistance, as demonstrated loss-of-function mutations...
Abstract Tongue squamous cell carcinoma (TSCC) is a prevalent malignancy that afflicts the head and neck area presents high incidence of metastasis invasion. Accurate diagnosis effective treatment are essential for enhancing quality life survival rates TSCC patients. The current modalities frequently suffer from lack specificity efficacy. Nanoparticles with diagnostic photothermal therapeutic properties may offer new approach targeted therapy TSCC. However, inadequate accumulation...
Powdery mildew, caused by the fungus Blumeria graminis f. sp. tritici, represents a yield constraint in many parts of world. Here, introduction resistance gene carried cereal rye cv. Qinling chromosome 6R was transferred into wheat form spontaneous balanced translocation induced plants doubly monosomic for chromosomes and 6A. The translocation, along with other structural variants, detected using situ hybridization genetic markers. differential disease response harboring various fragments...
Aegilops tauschii is the donor of bread wheat D genome. Based on spike morphology, taxon has conventionally been subdivided into ssp. and strangulata. The present study was intended to address poor match between this whole plant morphology-based subdivision genetic relationships inferred from genotyping by fluorescence in situ hybridization karyotyping a set 31 Ae. accessions.The distribution sites hybridizing two probes oligo-pTa-535 (CTT)10 split accessions clades, designated Dt Ds, which...
The formation of an allopolyploid is a two step process, comprising initial wide hybridization event, which later followed by whole genome doubling. Both processes can affect the transcription homoeologues. Here, RNA-Seq was used to obtain genome-wide leaf transcriptome independent Triticum turgidum × Aegilops tauschii allotriploids (F1), along with their spontaneous allohexaploids (S1) and parental lines. resulting sequence data were then characterize variation in homoeologue transcript...
The common wheat landrace Chinese Spring (CS) was made famous by the work of Ernie Sears, a great cytogenetist, who developed number CS-based aneuploid series that were used to identify individual chromosomes. Based on this, standard karyotype and nomenclature system for chromosomes allowed researchers analyze manipulate genome with unprecedented precision efficiency. Nevertheless, not much is known about utilization CS at its hometown, Chengdu in Sichuan province, during early breeding...
Stripe rust, caused by Puccinia striiformis f. sp. tritici, is one of the most destructive diseases in wheat production. Pyramiding adult-plant resistance (APR) genes a promising strategy to increase durability resistance. The stripe rust (R) Yr18, Yr28, and Yr36 encode different protein families which confer partial broad array P. tritici races. Here, we developed BC 3 F 5 lines representing all possible combinations genetic background highly tritici-susceptible line SY95-71 that widely...
The ph-like genes in the Chinese common wheat landrace Kaixian-luohanmai (KL) induce homoeologous pairing hybrids with alien species. In present study, meiotic phenotypic differences on chromosome at metaphase I between of genotypes Spring ph1b (CSph1b) and KL rye were studied by genomic situ hybridization (GISH). frequency wheat–wheat associations was higher CSph1b × than rye. However, frequencies wheat–rye rye–rye These may be result different mechanisms control gene(s) controlling CSph1b....
Stripe rust, caused by
Wild relatives have substantial impacts on the resistance of wheat to biotic and abiotic stresses. The genetic diversity these wild varieties can be employed widen gene pool by introducing allele introgression genome structure variations. powdery mildew Pm13 was derived from relative species Aegilops longissima (S1S1, 2n = 2x 14) transferred into chromosome 3BS over 30 years. Until recently, it has not been widely used in breeding, possibly because linkage drag associated with or poor alien...
<title>Abstract</title> Leaf rust is a devastating fungal disease of wheat. Planting resistant wheat cultivars the most effective strategy to mitigate this threat. Here, we generate 10.51-gigabase chromosome-scale assembly durum landrace PI 192051. Using mutagenesis and transcriptome sequencing, identify leaf resistance gene <italic>Lr.ace-4A</italic> within recombination-sparse region 192051 demonstrate that identical previously designated <italic>Lr30</italic> in hexaploid...
Meiotic nonreduction resulting in unreduced gametes is thought to be the predominant mechanism underlying allopolyploid formation plants. Until now, however, its genetic base was largely unknown. The allohexaploid crop common wheat (Triticum aestivum L.), which originated from hybrids of T. turgidum L. with Aegilops tauschii Cosson, provides a model address this issue. Our observations meiosis pollen mother cells turgidum×Ae. indicated that first division restitution, exhibited prolonged...
Aegilops variabilis (UUSvSv), an important sources for wheat improvement, originated from chromosome doubling of a natural hybrid between Ae. umbellulata (UU) with longissima (SlSl). The karyotype was poorly characterized by fluorescent in situ hybridization (FISH). FISH probe combination pSc119.2, pTa71 and pTa-713 identified each the 14 pairs chromosomes. Our ideogram further used to detect carrying stripe rust resistance background lines developed crosses susceptible bread cultivar Yiyuan...