A5019200438- Fermentation and Sensory Analysis
- HER2/EGFR in Cancer Research
- Nuts composition and effects
- Histone Deacetylase Inhibitors Research
- Phytochemicals and Antioxidant Activities
- Regional Development and Environment
- Chemotherapy-induced cardiotoxicity and mitigation
- Natural product bioactivities and synthesis
- Food Quality and Safety Studies
- Plant biochemistry and biosynthesis
Handan College
2021
Harbin Medical University
2020-2021
Phytochemical investigation on the ethanol extract of green walnut husks (Juglans mandshurica Maxim.) led to isolation two previously unknown compounds, including a macrolide compound (13S)-8-oxo-(9E, 11E)-8-oxo-octadeca-9,11-dien-13-olide (1) and diarylheptanoid 1-(3'-methoxy-4'-hydroxyphenyl)-7-(3″,4″-dimethoxyphenyl)heptan-3-one (2), together with 19 known compounds. The structures these 21 compounds were elucidated by extensive analyses NMR HR-MS data, basis spectroscopic analysis.
PURPOSE This study aimed to investigate the changes in microRNA-130a (miR-130a) and its correlation with cardiotoxicity during epirubicin/cyclophosphamide followed by docetaxel plus trastuzumab (EC-D+T) adjuvant chemotherapy human epidermal growth factor receptor-2-positive (HER2⁺) breast cancer patients. METHODS A total of 72 HER2⁺ patients who underwent resection were scheduled receive EC-D+T therapy consecutively enrolled. The expression miR-130a (defined as any following situations: 1)...
Phytochemical investigation on the concentrate of Huangjing wine, resulted in isolation three new tyrosol derivatives 4'''-hydroxyphenethyl 2-(R)-hydroxy-3-phenylpropionate (1), 4'''-hydroxyphenethyl(4'-hydroxy-3'-methoxyphenyl)propionate (2) and 4''-hydroxyphenethyl ethyl succinate (3), together with 5 known compounds, ferulic acid (4), L-phenyllactic (5), hydroxytyrosol (6), dihydroferulic (7), cyclo(L-Pro-D-Tyr) (8). Their structures were elucidated using spectroscopic analysis by...