A5064607240- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Enhanced Recovery After Surgery
- RNA modifications and cancer
- Chromatin Remodeling and Cancer
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer-related gene regulation
- Gastric Cancer Management and Outcomes
- Cancer Mechanisms and Therapy
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Cancer, Lipids, and Metabolism
- Metastasis and carcinoma case studies
- Peptidase Inhibition and Analysis
- Colorectal Cancer Surgical Treatments
- Cancer, Hypoxia, and Metabolism
- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Peroxisome Proliferator-Activated Receptors
- Intestinal and Peritoneal Adhesions
- Ectopic Pregnancy Diagnosis and Management
- Cancer Risks and Factors
- Autophagy in Disease and Therapy
- Immune cells in cancer
Nanjing University of Chinese Medicine
2019-2025
Ningbo No. 2 Hospital
2017-2024
Guangzhou University of Chinese Medicine
2019-2024
Ningbo University
2018-2023
First Affiliated Hospital Zhejiang University
2023
University of Chinese Academy of Sciences
2019-2023
Jiangsu Province Hospital
2021
Yangzhou University
2016-2017
Zhejiang University
2009-2013
Nanjing Medical University
2012
Prostate cancer is the most common in men United States. Fucoidan a bioactive polysaccharide extracted mainly from algae. The aim of this study was to investigate anti-tumor and anti-angiogenic effects fucoidan both cell-based assays mouse xenograft model, as well clarify possible role JAK-STAT3 pathway protection. DU-145 human prostate cells were treated with 100–1000 μg/mL fucoidan. Cell viability, proliferation, migration tube formation studied using MTT, EdU, Transwell Matrigel assays,...
Prostate cancer is a common malignancy and the second leading cause of death in men. Elevated expression transcription factor FoxM1 c-Myc has been identified prostate cancer. However, potential mechanism elevated to development not identified. In this report, mRNA level was detected 30 para-cancer tissues. Then, we by real-time PCR Western blot after disturbance PC-3 cells. Whether could bind promoter ChIP assay. Finally, migratory, invasive, proliferative abilities overexpressing silencing...
Abstract Long noncoding RNA s (lnc s) have been proved to play important roles in carcinogenesis and development of numerous cancers, but their biological functions bladder cancer remain largely unknown. In this study, a novel lnc termed GAS 6‐ AS 2 were primary identified, its as well mechanisms regulating proliferation metastasis cells investigated. Clinically, was significantly up‐regulated tissues positively correlated with tumour stages poor prognosis. Moreover, expression also...
Due to a combination of high morbidity and lack effective treatments, gastric cancer (GC) remains major cause cancer-related death all over the world. H19, as paternally imprinted long noncoding RNA (lncRNA), has been found dysregulated in GC.The aim this study is elucidate specific mechanism H19 GC.Bioinformatic analysis quantitative real-time PCR were utilized test expression pattern GC tissues cell lines. Wound healing, transwell, immunofluorescence assay, Western blot assays conducted...
Robotic gastrectomy (RG) has progressed rapidly in the last decade, overcoming many obstacles laparoscopic technology. We compared surgical performance and short-term clinical outcomes between RG (LG). In total, 163 patients with gastric cancer were randomly treated (n=102) or LG (n=61). D2 lymphadenectomy was achieved all patients. Digestive tract reconstruction group performed by intracorporeal hand sewing, but extracorporeal anastomosis a 25-mm circular stapler linear stapler. Compared...
Fast track (IT) rehabilitation programmes have demonstrated advantages over traditional perioperative care after open colonic surgery; however. their contribution in recovery laparoscopic surgery is not clearly defined. This study was conducted to estimate the value of FT programme resections.This a randomized prospective controlled clinical trial. Ninety-nine consecutive patients underwent elective resection between February 2008 and March 2009. Forty-nine received multimodal as group 50...
Enhanced recovery after surgery (ERAS) protocols or fast-track (FT) programs enable a shorter hospital stay and lower complication rate. Minimally invasive (MIS) is associated with lesser trauma quicker in many elective abdominal surgeries. However, little known of the safety effectiveness made by ERAS combined MIS for gastric cancer. The purpose this study was to evaluate FT combination alone.We summarized an 11-year experience on cancer patients undergoing laparotomy minimally resection...
In this article, we set up a novel audio dataset named Gastrointestinal (GI) Sound Set which includes 6 kinds of body sounds Bowel sound, Speech, Snore, Cough, Groan, and Rub. We do sound event detection (SED) based on it, can accurately detect types events. First, the GI is collected by wearable auscultation devices. To ensure generalization, patients from five different hospital departments are recruited for data collection, along with group healthy subjects. refers to Google AudioSet in...
AIM:To increase attendance for colonoscopy among nonadherent high-risk individuals colorectal cancer (CRC) screening in China. METHODS:During the first 12 mo without intervention, only 428 of 2398 subjects attended a scheduled examination.The 1970 who did not attend CRC were enrolled present study.Prior barrier investigation was performed to ascertain reasons nonadherence.A barrier-focused intervention program then established and implemented eligible by telephone interviews on-site...
Prostate cancer (PCa) is the second most common type of and 6th leading cause cancer‑associated mortality worldwide. Accumulated evidence suggests that PCa initiation progression are controlled by microRNAs (miRNAs). Therefore, investigating PCa‑associated miRNAs may provide novel biomarkers for diagnosis treatment patients with PCa. In present study it was demonstrated miRNA‑136 (miR‑136) expression significantly downregulated in tissues cell lines. The resumption miR‑136 suppressed...
Background and Objectives: A significant role was played by costimulatory molecules in renal cancer. However, the lncRNAs regulating have not been fully investigated. Materials Methods: Data from next-sequence file clinical data were downloaded Cancer Genome Atlas (TCGA) database. All analyses conducted using R GraphPad Prism software. Results: total of 1736 molecule-related determined under threshold |Cor| > 0.5 p-value < 0.001. Furthermore, a prognosis prediction signature consisting...
This study aimed to investigate the dysregulated proteins and underlying mechanisms of gastric precancerous lesions. Proteomic phosphoproteomic methods were used characterize proteome phosphoproteome profiles
Abstract The surgical, oncologic, and functional outcomes were retrospectively compared of laparoscopic partial nephrectomy (LPN) open (OPN) for the treatment renal masses. Between January 2006 November 2011, 115 LPNs 97 OPNs performed. patients' demographics matched. Their intraoperative postoperative data, oncologic function compared. Surgical time, arterial occlusion estimated blood loss, hospitalization days shorter in LPN group ( p < 0.01). total complications comparable; however,...
Prostate cancer (PCa) is the most frequently diagnosed malignancy in men and its incidence has increased rapidly worldwide. Notably, molecular mechanisms underlying prostate tumorigenesis have not been fully identified. The levels of microRNA (miR)‑381 explored numerous types malignancy; however, expression biological function miR‑381 PCa remain largely unknown. In present study, reverse‑transcription polymerase chain reaction was used to detect cells normal epithelial cells. Subsequently,...
Colonic mucosal injuries are an important manifestation of ulcerative colitis (UC), which is related to hypoxia-induced glycolysis in colonic epithelial cells (cmECs). Panax notoginseng (PN) promotes the repair by inhibiting cmECs; However, mechanism this occurs not completely clear. Here, we investigate effects PN on glucose metabolism cmECs and underlying mechanism.A model dextran sulfate sodium-induced rats was used research, severity assessed pathology, disease activity index (DAI),...
Enolase 2 (ENO2) has increasingly been documented in multiple cancers recent years. However, the role of ENO2 clear cell renal carcinoma (ccRCC) not fully explored. In present study, open-access data were downloaded from The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), and Human Protein (HPA) databases. All statistical analyses performed R GraphPad Prism 8 softwares. Results showed that was overexpressed ccRCC tissues lines correlated with worse clinical features prognosis....
Prostate cancer places a serious health burden on males. The present study aimed to explore the potential prognostic significance and biological function of microRNA (miR)‑339‑5p in patients with prostate cancer. expression miR‑339‑5p was detected tissues cell lines by using reverse transcription‑quantitative PCR. Kaplan‑Meier survival curves Cox regression analyses were used investigate Cell Counting Kit‑8 assay determine effect proliferation. Transwell assays assess migration invasion....