A5101612780- Pharmaceutical and Antibiotic Environmental Impacts
- Forest, Soil, and Plant Ecology in China
- Toxoplasma gondii Research Studies
- Herpesvirus Infections and Treatments
- Remote Sensing and Land Use
- Environmental Changes in China
- Toxin Mechanisms and Immunotoxins
- Rabies epidemiology and control
- Forest Management and Policy
- Water Treatment and Disinfection
- Pharmacological Effects of Natural Compounds
- Advanced oxidation water treatment
- Water Quality Monitoring and Analysis
- Antibiotics Pharmacokinetics and Efficacy
- Bioactive Compounds and Antitumor Agents
- Legume Nitrogen Fixing Symbiosis
- Food Quality and Safety Studies
- Aquatic Ecosystems and Phytoplankton Dynamics
- Advanced biosensing and bioanalysis techniques
- Aquaculture disease management and microbiota
- Meat and Animal Product Quality
- Antibiotic Resistance in Bacteria
- Traditional Chinese Medicine Studies
- Cytomegalovirus and herpesvirus research
- Cancer therapeutics and mechanisms
Huaiyin Normal University
2024-2025
Qiqihar Medical University
2024
Nanjing Forestry University
2016-2023
Shanghai Jiao Tong University
2021
Yunnan Center for Disease Control And Prevention
2020
Nanjing Institute of Geography and Limnology
2020
Hainan Medical University
2020
Harbin Medical University
2018
Lanzhou University
2013-2017
Lanzhou City University
2017
ABSTRACT A model DNA microarray has been prepared and shown to facilitate typing subtyping of human influenza B viruses. Reverse transcriptase PCR was used prepare cDNAs encoding ∼500-bp virus gene fragments, which were then cloned, sequenced, reamplified, spotted form a glass-bound microarray. These target DNAs included multiple fragments the hemagglutinin, neuraminidase, matrix protein genes. Cy3- or Cy5-labeled fluorescent probes hybridized these DNAs, arrays scanned determine probe...
A europium functionalized silicon nanoparticle (SiNP) ratiometric fluorescence transducer based on FRET was designed to detect tetracycline (TC) with high sensitivity and selectivity.
The ecological effects of antibiotics in surface water have attracted increasing research attention. In this study, we investigated the combined ecotoxicity erythromycin (ERY) and roxithromycin (ROX) on microalgae, Chlorella pyrenoidosa, removal ERY ROX during exposure. calculated 96-h median effect concentration (EC50) values ERY, ROX, their mixture (2:1 w/w) were 7.37, 3.54, 7.91 mg∙L-1, respectively. However, predicted EC50 ERY+ROX 5.42 1.51 based addition independent action models, This...
Shikonin (SHK) has been proven to have a good anti-tumor effect. However, poor water solubility and low bioavailability limit its wide application in clinical practice. In this study, overcome these drawbacks, RGD-modified shikonin-loaded liposomes (RGD-SSLs-SHK) were successfully prepared. It exhibited excellent physicochemical characteristics including particle size, zeta potential, encapsulation efficiency, delayed release time. Meanwhile, the targeting activity of was demonstrated by...
Toxoplasmosis, caused by the obligate intracellular parasite Toxoplasma gondii, is an important zoonotic disease worldwide. The precise detection of T. gondii infection in dogs has public health significance. In this study, recombinant granule antigen proteins GRA1 and GRA7 were evaluated as potential diagnostic markers for indirect enzyme-linked immunosorbent assay (ELISA). cloned expressed Escherichia coli, GRA1, GRA7- lysate (TLA)-based ELISAs developed using canine positive negative...
Macrolide pollution has attracted a great deal of attention because its ecotoxic effects on microalgae, but the role phycospheric bacteria under antibiotic stress remains unclear. This study explored toxic erythromycin (ERY) growth and nitrogen metabolism Auxenochlorella pyrenoidosa; then, it analyzed predicted composition ecological function microalgae ERY stress. We found that 0.1, 1.0, 10 mg/L inhibited chlorophyll gradually showed enhanced abilities over course 21 days. As exposure time...
Background/Objectives Breast cancer treatment remains challenged by the non-specific distribution and systemic toxicity of conventional chemotherapeutics. Celastrol (CEL), a natural compound with antitumor efficacy, faces clinical limitations due to its poor solubility. Glycyrrhizic acid (GA), known for tumor-suppressive membrane-modifying properties, offers potential enhance targeted drug delivery. This study aimed develop GA-modified liposomes (GA/LIP-CEL) synergistically improve CEL’s...
ABSTRACT We detected Toxoplasma gondii in 29.3% (95% confidence interval [CI], 25.5% to 33.1%) of 550 insectivorous bats collected Myanmar. The genotyping these positive samples revealed they were closely related or belong clonal type I, which is highly virulent mice, showing that are potential reservoirs for T. transmission.
Melanoma is the most aggressive skin tumor, and conventional treatment ineffective. Studies have shown that shikonin, derived from traditional Chinese medicine Lithospermum erythrorhizon , has various anticancer activities. In this work, RGD- modified liposomes encapsulated with shikonin (RGD-Lip-SHK) were prepared by thin- film dispersion, which could highly recognize integrin α V β 3 on surface of melanoma cells. RGD-Lip-SHK appeared as spheroid-like vesicles a particle size approximately...
Semiconducting wood/polyaniline (PANI) composites were synthesized via in situ polymerization of aniline monomer, which was impregnated into the wood veneer advance. Thus, resulting exhibited characteristics conducting PANI and natural wood. The light microscopy scanning electron images showed that uniformly dispersed substrate. weight percent gain volume bulk increase 16.13% 6.21%, respectively. equilibrium water absorption studies less hydrophilic, because addition hydrophobic PANI....
The precise detection of Toxoplasma gondii infection in cats has important public health significance. In the present study, recombinant granule antigen protein GRA7 was evaluated as a potential diagnostic marker for T. by an indirect enzyme-linked immunosorbent assay (ELISA), using classified serum samples from cats, immunofluorescence (IFA) and modified agglutination test (MAT). There perfect agreement (97.2%) between GRA7-ELISA MAT/IFA (Kappa = 0.92; 95% confidence interval [CI], 0.85 to...
We have recently proposed that one way plant growth-promoting rhizobacteria (PGPR) stimulate growth is through the activity of enzyme 1-aminocyclopropane-1-carboxylate (ACC) deaminase, which causes a lowering ethylene levels resulting in longer roots. As part an effort to understand role this PGPR, genes for ACC deaminase from two Enterobacter cloacae CAL2 and UW4, been isolated. These are highly homologous Pseudomonas strains 6G5 F17 similar gene sp. strain ACP. The region downstream (i.e.,...