A5054630164- Estrogen and related hormone effects
- Sperm and Testicular Function
- Comparative Animal Anatomy Studies
- Hormonal and reproductive studies
- Animal Nutrition and Physiology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Prostate Cancer Treatment and Research
- Pesticide Exposure and Toxicity
- Evolution and Paleontology Studies
- Hypothalamic control of reproductive hormones
- Pesticide and Herbicide Environmental Studies
- Avian ecology and behavior
- Paleontology and Evolutionary Biology
- Vitamin D Research Studies
- Bat Biology and Ecology Studies
- Animal Behavior and Reproduction
- Ion Transport and Channel Regulation
- Electrolyte and hormonal disorders
- Animal Genetics and Reproduction
- Acne and Rosacea Treatments and Effects
- Dermatology and Skin Diseases
- Healthcare and Venom Research
- Bird parasitology and diseases
- Coccidia and coccidiosis research
- Fish biology, ecology, and behavior
Universidade Federal de Minas Gerais
2012-2024
Instituto de Ciencias Tecnológicas
2009
Pontifícia Universidade Católica de Minas Gerais
1983
Drug‐induced liver injury (DILI) is an important cause of acute failure, with limited therapeutic options. During DILI, oncotic necrosis concomitant release and recognition intracellular content amplifies inflammation injury. Among these molecules, self‐DNA has been widely shown to trigger inflammatory autoimmune diseases; however, whether DNA released from damaged hepatocytes accumulates into necrotic the impact its by immune system remains elusive. Here we show that treatment two different...
This work aims to investigate the influence of formation ion pairing between all-trans retinoic acid (RA) and a lipophilic amine (stearylamine; STE) on drug encapsulation efficiency (EE) stability solid lipid nanoparticles (SLNs). The SLNs were characterized for EE size. particle size significantly improved reduced, respectively, when surfactant or co-surfactant concentration increased. However, while formulation without STE allowed only 13% RA encapsulation, RA-STE-loaded was 94%. studies...
Estrogen receptors, in addition to the androgen receptor (AR), are expressed at high levels efferent ductules of male reproductive tract and it is now well recognized that estrogen (ER) α required for maintenance normal structure function ductules. However, little known regarding hormonal regulation receptors themselves male. In present study, ductule ligation castration, followed by replacement with testosterone, dihydro-testosterone (DHT) or estradiol was used investigate relative...
Abstract Background Fluid homeostasis is critical for normal function of the male reproductive tract and aquaporins (AQP) play an important role in maintenance this water ion balance. Several AQPs have been identified male, but their regulation not fully comprehended. Hormonal appears to be dependent on steroid region. AQP9 displays unique hormonal efferent ductules epididymis, as it regulated by both estrogen dihydrotestosterone (DHT) ductules, only DHT initial segment epididymis. Recent...
The «Gruta das Oncas», a cave situated in the Caatinga do Moura district, municipulity of Jacobina, Bahia State, has been rich source fossils (Cartelle & Bohorquez, 1982 and Cartelle, 1983). In this same fossil bed we have found large quantities skeletal pieces Eremotherium laurillardi (Lund, 1842), together voith Nothrotherium maquinense Lydekker, 1889, Smilodon populator Lund, 1842 series giant armadillo vohich is object our present study. study given special emphasis to cranium;...
Chemical hosts bind their guests by the same physical mechanisms as biomolecules and often display similarly subtle structure activity relationships. The cyclodextrins have found increasing application inert, nontoxic carriers of active compounds in drug formulations. present study was conducted to prepare inclusion complexes chlorhexidine:β-cyclodextrin (Cx:β-cd), evaluate interactions with bacterial membrane through: scanning electron microscopy (SEM) transmission (TEM); measuring...
Abstract Cloacas of 67 avian species, both sexes, from various habitats and differing dietary habits, were examined macro‐ microscopically to investigate possible variation in the location ureteral openings. Differing most birds studied, adult male Rhea americana several tinamous species ureters found open into coprodeum. In these urodeum receives only vas deferens or oviduct. Similarly, crocodiles Caiman crocodilus yacare , but not lizards Tropidurus montanus snakes Crotalus durissus...
Estrogen signaling is required for the maintenance of male reproductive function and mediated by estrogen receptors ERα ERβ. These are widely distributed in mammalian tissues, but information limited non-mammalian species including birds. The aim this study was to investigate occurrence cellular distribution ERβ testis epididymal region roosters. results showed first time that predominant receptor detected testis, being expressed somatic some germ cells. Within region, strongly all segments,...
Efferent ductules and epididymis are involved in water solute transport, which is indispensable for storage maintenance of the sperm viability. The reabsorption process involves proteins such as aquaporins (AQP), has been described male genital system limited species, including primate, rodents, cats dogs. To contribute with information about AQPs system, here we investigated distribution AQP1 AQP9 tropical bat Artibeus lituratus, along annual reproductive cycle. A. lituratus a seasonal...
Abstract The tongue of anteaters (Xenarthra, Pilosa, Vermilingua) is a highly specialized for myrmecophagy. Here, we describe the topography and histology tongue, compare it to that other xenarthrans myrmecophagous eutherian mammals. Vermilingua long slender, with an apical protuberance, which differs between Myrmecophagidae Cyclopes didactylus . In former, rostral region conical, in latter, dorsoventrally compressed, as observed sloths. has filiform circumvallate papillae on surface;...
Although the prostate is androgen-dependent, it also influenced by estrogens, which act via estrogen receptors ERα and ERβ. In prostate, ERβ highly expressed in epithelium appears to participate regulation of cell proliferation, apoptosis differentiation. Evidence shows that decreased malignant suggesting plays an important role protecting this tissue. Despite relationship between reductions abnormal growth gland, little known about age-dependent variation receptor. Therefore, we aimed...
BACKGROUND Estrogens acting through the receptors ERα and ERβ participate in prostate normal growth cancer. is highly expressed epithelium, playing pro‐apoptotic, anti‐proliferative, pro‐differentiation roles. Apoptosis activated by intrinsic pathway after castration extrinsic agonist treatment. This differential activation of apoptotic pathways important since a major problem treatment cancer recurrence tumors androgen withdrawal. However, comprehensive study about pattern apoptosis aging...
Protective roles have been proposed for vitamin D in prostate cancer, which has the advanced age as major risk factor. However, little is known about expression of receptor (VDR) aging and its association with development epithelial lesions that affect tissue homeostasis may precede tumors.VDR prostatic complex young adults to senile Wistar rats, a natural model study age-related disorders, was evaluated by immunohistochemical, Western blotting, image-assisted analyzes. Results were...
The efferent ductules (ED) are a major target for estrogens, which act via the estrogen receptors ERα (ESR1) and ERβ (ESR2). has been found in ED of all species studied so far. However, epididymis (EP), expression is controversial, as data about occurrence aromatase epithelium lining excurrent ducts. Therefore, to further investigate this estrogen-responsive system, we used seasonal breeder, Neotropical bat, Artibeus lituratus, testicular androgen (AR) (ER) vary with reproductive phase....
The widely used herbicide atrazine is a potent endocrine disruptor known to cause increased aromatase expression and transient increase in testicular weight followed by remarkable testis atrophy. However, whether the effects of on testes are primary or secondary dysfunctions other components male reproductive tract remains unknown. Given high sensitivity efferent ductules estrogen imbalance similarity alterations previously described for disruptors these function, observed after exposure, we...