A5006802083- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Science and Education Research
- Tuberculosis Research and Epidemiology
- Health, Nursing, Elderly Care
- Education during COVID-19 pandemic
- HIV/AIDS oral health manifestations
- Public Health in Brazil
- Fungal Infections and Studies
- Hepatitis C virus research
- Maternal and Neonatal Healthcare
- Leprosy Research and Treatment
- Hepatitis B Virus Studies
- SARS-CoV-2 and COVID-19 Research
- Healthcare during COVID-19 Pandemic
- Healthcare Regulation
- Women's cancer prevention and management
- Biotechnology and Related Fields
- Academic Research in Diverse Fields
- vaccines and immunoinformatics approaches
- Nail Diseases and Treatments
- HIV, Drug Use, Sexual Risk
- Antifungal resistance and susceptibility
- T-cell and Retrovirus Studies
Centro Universitário Lusíada
2014-2023
Universidade Santa Cecília
2020
Prefeitura do Município de São Paulo
2019
University of Lusaka
2013-2018
Universidade Federal de São Paulo
2003-2017
Union des Industries Ferroviaires Européennes
2016-2017
Lusíada University of Lisbon
2013
Universidade Católica de Santos
2005-2012
San Francisco AIDS Foundation
2003
University of California, Berkeley
2003
The environmental contamination by geohelminths represents a world public health problem and has been well documented several authors. However, few papers describe the presence of such in saline soils coastal beaches. A study was performed on beaches municipality Santos period between May 2004 to April 2005 with aim determining degree contamination, correlation level seasonal conditions characteristics environment. Of 2,520 samples analyzed, 18.2% (458) were contaminated, 32.3% (148) which...
Summary: The Brazilian Network for HIV Isolation and Characterization was established the surveillance of variability in Brazil. Here, we report characterization strains virus-specific immune responses from 35 clinical samples collected three potential vaccine sites. Three genetic subtypes HIV-1 were identified by heteroduplex mobility assay (HMA) B (in 82.9% samples), F (14.3%), C (2.9%). Phylogenetic analysis based on C2V3/env DNA sequence all 25 specimens examined 100% concordant with HMA...
This study characterized HIV-1 among antiretroviral-naïve populations presenting recent infection (RI) or long-standing (LSI). Sera collected from January 1999 to December 2001 at an anonymous HIV testing site in Santos, Brazil, were submitted serologic algorithm for seroconversion (STARHS). The STARHS methodology uses a combination of sensitive and less version anti-HIV enzyme immunoassay (EIA), specimens found be positive on the EIA negative are considered represent RI. V3 pol regions...
Summary: The Brazilian Network for HIV Isolation and Characterization was established the surveillance of variability in Brazil. Here, we report characterization strains virus-specific immune responses from 35 clinical samples collected three potential vaccine sites. Three genetic subtypes HIV-1 were identified by heteroduplex mobility assay (HMA) B (in 82.9% samples), F (14.3%), C (2.9%). Phylogenetic analysis based on C2V3/env DNA sequence all 25 specimens examined 100% concordant with HMA...
ABSTRACT Objective Ascertain the prevalence of depressive and anxiety symptoms in medical students, considering data literature that indicate higher vulnerability to emotional disorders this population. Methods A descriptive cross-sectional study with a sample 657 (98%) students. The instruments used were: questionnaire socioeconomic-demographic characteristics, Beck Depression Inventory Anxiety Inventory. Results Predominance female gender (61%), aged between 17 30 years (98%), Catholic...
In Brazil, the use of antiretrovirals is widespread: more than 260,000 individuals are currently undergoing treatment. We conducted a survey targeting antiretroviral-naïve who were initiating antiretroviral therapy (ART) according to local guidelines. This covered five Brazilian regions.The HIV Threshold Survey methodology (HIV-THS) World Health Organization was utilized, and subjects selected from seven highly populated cities representative all macro-regions. Dried blood spots (DBS)...
This study involved a total of 116 samples, 79 taken from pigeon droppings and 37 atmospheric air close to accumulations excrement. Cryptococcus neoformans var. grubii was isolated 11 (13.9%) these samples. Other species were also such as C. albidus (12.6%) laurentii (8.9%). not the though (5.4%) was. All strains found belong A serotype (C. grubii). In regard studies with antifungal agents 5-fluorocytosine, fluconazole, itraconazole, amphotericin B voriconazole, by means microdilution method...
Acanthamoeba and Naegleria species are free-living amoebae (FLA) found in a large variety of natural habitats. The prevalence such was determined from dust samples taken public non-hospital internal environments with good standards cleanliness two campuses the same University city Santos (SP), Brazil, where young apparently healthy people circulate. frequency both campuseswas 39% 17% respectively, predominance genus Acanthamoeba. On campus much larger number circulating individuals, observed...
Objectives To determine temporal trends in HIV infection and risk factors among persons seeking anonymous testing Santos, Brazil. Methods Data sera from for 1996 to 1999 were used. Exposures abstracted assessments. Stored HIV-positive tested identify recently acquired using a serologic algorithm detecting recent seroconversion (STARHS). Independent associations between exposures determined multivariate analyses. Results Overall, estimated incidence was 2.0% (95% CI: 1.1–3.5) the 4-year...
HIV-1 antiretroviral drug resistance mutations in subtype B, F, and recombinants B/F Santos, Brazil were characterized. We studied 83 samples from individuals enrolled at the Brazilian HIV/AIDS programs Santos. These patients have been treated with multiantiretroviral therapy. Samples collected 2006; RNA was extracted plasma used as a target to amplify pol gene of HIV-1. PCR products sequenced on both strands, phylogenetic analyses performed by neighbor-joining, recombination evaluated...
We characterized the virologic failure after an initially successful 48-week course of antiretroviral therapy among HIV/AIDS patients in a retrospective cohort study involving from Santos, Brazil. Patients with plasma HIV RNA below 500 copies/mL for 48 weeks were included. Variables analyzed included gender, age, level education, marital status, mode acquisition, viral load, and CD4 cell count upon admission. There 4,909 registered clinic, which 669 met all inclusion criteria (41.6% female...
Continuous long-term treatment is recommended to reduce the hepatitis B virus (HBV) viral load. However, as a consequence, resistance mutations can emerge and be transmitted other individuals. The polymerase (POL) gene overlaps surface (S) gene. Thus, during treatment, in POL may lead changes antigen (HBsAg). purpose of this study was evaluate frequency lamivudine vaccine escape HBsAg-positive blood donors from city Santos untreated HBV mono-infected patients São Paulo, Brazil.HBV DNA...
In order to assess the molecular epidemiology of HIV-1 in two neighboring cities located near epicenter epidemics Brazil (Santos and São Paulo), we investigated 83 strains obtained from samples collected 1995 intravenous drug users. The V3 through V5 region envelope gp 120 was analyzed by heteroduplex mobility analysis. Of 95 samples, 12 (12.6%) were PCR negative (6 each group); low DNA concentration reason for non-amplification half these cases. 42 typed cases Paulo, 34 (81%, 95% confidence...
HIV-1 from infected subjects has been characterized in order to provide a more accurate view of the strains that are currently found given region. In this report, we focused on characterizing pol gene diversity obtained newly diagnosed patients Santos metropolitan area, Brazil. This region is composed nine cities and an international port. Analysis 33 samples revealed 22 belonged subtype B, 4 F, 2 C; 5 were B/F recombinants. Our results demonstrated 18.2% primary antiretroviral resistance...
Santos is a Brazilian port city with high HIV incidence, primary antiretroviral resistance levels, HIV-1 BF recombinants prevalence, and rates of virologic failure. We evaluated factors related to failure after 48 weeks HAART in this population. compared demographic profiles among 43 individuals (group 1) 37 success 2) initiation. The overall prevalence was 31.2%; 46.5% group 1 13.5% 2 (p < 0.005). Nine patients from seven were infected by F or strains. Fifteen presented NRTI mutations, 13...
Advancements in next-generation sequencing and bioinformatics have expanded our knowledge of the diversity viruses (pathogens non-pathogens) harbored by mosquitoes. Hubei reo-like virus 7 (HRLV 7) was recently detected virome analysis fecal samples from migratory birds Australia. We now report detection RNA-dependent RNA polymerase sequences HRLV pools Aedes aegypti Culex quinquefasciatus mosquitoes species Brazilian Amazon forest. Phylogenetic inferences indicated that all strains fall...
RESUMO A Covid-19 chegou rapidamente à periferia das grandes cidades brasileiras, a qual é socialmente mais vulnerável. baixa capacidade de testagem resulta na adoção medidas sem informações consistentes sobre o comportamento da doença e interfere ações controle. Objetivou-se estimar prevalência infecção por SARS-CoV-2 população Região Metropolitana Baixada Santista (RMBS) analisar impactos vulnerabilidade social políticas públicas implementadas em contextos desigualdades. Estudo caráter...
The first case of Paracoccidioides brasiliensis in Santos (Brazil) leading to septicemia and death an HIV-positive patient is reported here. was a 34-year-old female that presented essential fever only diagnosed after by positive blood culture. authors underscore the atypical nature case, since at fertile age who born had always lived Santos, which nonendemic area for this infection.
Hepatitis C virus (HCV) infection is an important public health issue worldwide. It estimated that over 170 million people are infected with the virus. The present study reports six cases in which patients did not respond to combination therapy pegylated interferon and ribavirin. However, after addition of thalidomide therapy, presented negative RNA PCR. use combined ribavirin for treatment hepatitis described here first time related literature.
ABSTRACT Background Infection with SARS-CoV-2, associated severe respiratory symptoms, currently called COVID-19, represents one of the greatest health challenges this century. Health professionals, as well hospital workers, are most vulnerable population for acquiring SARS-CoV-2 due to their greater proximity sick patients, especially in specialized hospitals treatment these patients. Study Design We ran a questionnaire by all employees Public Service Hospital specialised COVID-19 (1307...