A5010811121- Acupuncture Treatment Research Studies
- Traditional Chinese Medicine Studies
- Psychosomatic Disorders and Their Treatments
- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Complementary and Alternative Medicine Studies
- Liver Disease Diagnosis and Treatment
- Pain Management and Placebo Effect
- Migraine and Headache Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Gut microbiota and health
- Metabolomics and Mass Spectrometry Studies
- Circadian rhythm and melatonin
- Diet and metabolism studies
- Alzheimer's disease research and treatments
- Sleep and Wakefulness Research
- Sleep and related disorders
- Alcohol Consumption and Health Effects
- Hereditary Neurological Disorders
- Neurological Disease Mechanisms and Treatments
- Advanced Neuroimaging Techniques and Applications
- Metabolism, Diabetes, and Cancer
- Medicinal Plants and Neuroprotection
Changchun University of Chinese Medicine
2019-2024
Changchun University
2023
Abstract Background The clinical efficacy of electroacupuncture in treating diabetic peripheral neuropathy (DPN) is significant, but the underlying mechanism action not clear. Considering that glucose‐regulated protein 78 (GRP78) and caspase‐12 are major proteins participating cell apoptosis, we investigated effects “adjusting internal organs dredging channel” therapy on GRP78 levels streptozotocin (STZ)‐diabetic rats to elucidate action. Methods Rats were first divided into two groups: one...
Traditional Chinese acupuncture has been demonstrated to be beneficial for treatment of type 2 diabetes mellitus (T2DM). The mechanism on T2DM is crucial their biological activity as well usefulness tools in biology and medicine. However, its poorly understood.In an effort explore the mechanism, eight db/db mice (a spontaneous mouse) were treated with adjusting internal organs dredging channel electroacupuncture (AODCEA) weeks. Another fed group (T2DMG), db/m set normal control (NCG)....
Abstract To investigate the effect mechanism of electroacupuncture based on AMP-activated protein kinase (AMPK) /acetyl-CoA carboxylase (ACC) signaling pathway to improve glycolipid metabolism disorders in db/db mice. 10 db/m mice with normal genotype were used as control group without diabetes (Con), and 30 divided randomly into three groups: Pathological model (Mod), Acupuncture + ACC antagonist (Acu ACC), AMPK AMPK). Con Mod did not receive any special treatment, only a observation. The...
Abstract Objective: To explore the proteomics profiles of hepatocytes mice treated with acupuncture for type 2 diabetes mellitus (T2DM) non-alcoholic fatty liver disease (NAFLD). Methods: We used a Tandem mass tag (TMT)-based quantitative approach to identify proteins potential molecular mechanisms associated interventions T2DM NAFLD. Results: Acupuncture effectively improved body weight, blood glucose, and insulin levels in NAFLD mouse models reversed steatosis within hepatocytes....
Introduction Diabetic cognitive impairment (DCI) is a chronic complication of the central nervous system (CNS) caused by diabetes that affects learning and memory capacities over time. Recently, acupuncture has been shown to improve in streptozotocin-induced diabetic rats. However, effects electroacupuncture on DCI its underlying mechanism have not yet elucidated detail. Methods In this study, we used db/db mice as animal models which showed low cognitive, functions. Electroacupuncture...
Diabetic cognitive impairment (DCI) is a serious chronic complication caused by diabetes. The pathogenesis of DCI complex, but brain nerve injury and cell apoptosis are important pathological changes. Multimodal imaging one the most techniques to study neural mechanism brain. For clinical treatment DCI, there no effective targeted Western medicine lack clear drug intervention methods. Therefore, an urgent need find complementary alternative methods clarify their mechanism. This research...
The published evidence on the effectiveness and safety of acupuncture people with dementia has been inconsistent. This systematic review overviews aims to summarize evaluate from relevant reviews (SRs) meta-analyses provide reliable for future clinical treatment. We searched PubMed, EMBASE, Web Science, Cochrane Library, Database Systematic Reviews, DARE, Google Scholar, CNKI, VIP, CBM Wangfang establishment databases January 2020. types based pathology mainly include Alzheimer's disease...
Abstract Background Painful diabetic peripheral neuropathy (PDPN) has a great impact on an individual’s quality of life. The current researchers’ previous trial suggested that acupuncture was promising adjunctive treatment for PDPN. However, the underlying mechanism action PDPN is still unclear, especially its effects at cerebral level. aim this will be to explore how works in treating by using multimodal imaging. Method and design This randomized controlled trial. A total 150 participants...
To investigate the cerebral metabolism in patients with type 2 diabetes mellitus-associated cognitive dysfunction (T2DACD) and explore mechanism of electroacupuncture (EA) at acupoints for Tiaozang Xingshen (adjusting zangfu function rescuing spirit) treatment T2DACD, using magnetic resonance spectroscopy.Fifteen T2DACD (observation group) 22 healthy subjects (control were enrolled. In observation group, treated EA Baihui (GV 20) Shenting 24), bilateral Feishu (BL 13), Pishu 20), Shenshu...