Esteban Sepúlveda

ORCID: 0000-0003-3039-0022
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About
Contact & Profiles
Research Areas
  • Intensive Care Unit Cognitive Disorders
  • Dementia and Cognitive Impairment Research
  • Anesthesia and Sedative Agents
  • Geriatric Care and Nursing Homes
  • Psychosomatic Disorders and Their Treatments
  • Alcoholism and Thiamine Deficiency
  • Seventeenth-Century Political and Philosophical Thought
  • Anesthesia and Neurotoxicity Research
  • Cardiovascular Syncope and Autonomic Disorders
  • Healthcare Decision-Making and Restraints
  • Philosophical and Cultural Analysis
  • 3D Shape Modeling and Analysis
  • Scientific Research and Technology
  • Frailty in Older Adults
  • Forensic Toxicology and Drug Analysis
  • Multiple Sclerosis Research Studies
  • Pharmacology and Obesity Treatment
  • Advanced Radiotherapy Techniques
  • Electroconvulsive Therapy Studies
  • Peripheral Nerve Disorders
  • Social Issues and Policies in Latin America
  • Clinical practice guidelines implementation
  • Historical Studies in Latin America
  • Public Health and Environmental Issues
  • Philosophical Thought and Analysis

Institut d'Investigació Sanitària Pere Virgili
2014-2025

Institut Pere Mata
2014-2025

Instituto de Salud Carlos III
2024-2025

Boston Medical Center
2025

Centro de Investigación Biomédica en Red de Salud Mental
2014-2024

Universitat Rovira i Virgili
2014-2024

Hospital Universitario Dr José Eleuterio Gonzalez
2023

Centro de Investigación Biomédica en Red
2014-2022

Diego Portales University
2022

McGill University
2020

Information on validity and reliability of delirium criteria is necessary for clinicians, researchers, further developments DSM or ICD. We compare four ICD diagnostic versions, which were developed by consensus experts, with a phenomenology-based natural diagnosis delineated using cluster analysis features in sample high prevalence dementia. also measured inter-rater each system when applied two evaluators from distinct disciplines. Cross-sectional 200 consecutive patients admitted to...

10.1186/s12888-016-0878-6 article EN cc-by BMC Psychiatry 2016-05-26

Abstract Introduction Subsyndromal delirium (SSD) complicates diagnosis of and dementia, although there is little research comparing their symptom profiles. Methods Cross‐sectional study 400 elderly patients' admission to a general hospital or nursing home diagnosed with delirium, SSD, no‐delirium/no‐dementia (NDND). Symptom profiles were assessed using the Delirium Rating Scale‐Revised‐98 (DRS‐R98). Results Twenty percent patients had 19.3% 29.8% dementia‐only, 31% NDND. Eighty‐one...

10.1016/j.dadm.2016.11.002 article EN cc-by-nc-nd Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring 2016-12-01
Marte Z. van der Horst Nini de Boer Ahmet Müderrisoğlu Alba Toll Alde Bouhuis and 85 more Alkomiet Hasan Amy Jongkind Ana González‐Pinto Anna Mané Armando D’Agostino Aygün Ertuğrul A. Elif Anıl Yağcıoğlu Benedicto Crespo‐Facorro Bernhard T. Baune Bianca Sánchez-Barbero Carlos Spuch Carla Lou Morgenroth Carmen Fernandez de Pinedo Cecilia Casetta Chad A. Bousman Christa Hohoff Christos Pantelis Claudia Ovejas-Catalán Clemente García‐Rizo Dan Cohen Dragana Ignjatović Ristić Edwin Beld Eila Repo‐Tiihonen Elias Wagner Ellen Jeger-Land Elisabet Vilella Emilio Fernández-Egea Erwin Bekema Esteban Sepúlveda Federico Wiedenmann Francesca Martini Francesca Serio Francesca Vairano Giacomo Mercuriali Giovanni Boido Gökhan Yoca Hanneke van Beek Harm J. Gijsman Heli Tuppurainen Ian Everall Ivona Novakovic Eric P. Zorrilla İbrahim Mert Erdoğan Jacopo Sapienza Jan Bogers Jari Tiihonen Javier Vázquez‐Bourgon Jim van Os Johannes Schneider‐Thoma Jurjen J. Luykx Koen P. Grootens Lorea Mar‐Barrutia Lourdes Martorell Maarten Bak Marco Spangaro Marco Zierhut Marije de Vos Mariken de Koning Marina Garriga Markku Lähteenvuo Marta Bosia Marte Z. van der Horst Melih O. Babaoğlu Mike Veereschild Mirko Manchia Mishal Qubad Monika Edlinger Paloma Fuentes-Pérez Pasquale Paribello Purificación López-Peña René S. Kahn Robert A. Bittner Roberto Cavallaro Selene Veerman Stefan Gutwinski Stefanie Schreiter Stephan Ripke Tania Rivera Baltanás Tatiana Oviedo-Salcedo Tero Hallikainen Thomas Görlitz Wouter Alink Yavuz Ayhan Cynthia Okhuijsen‐Pfeifer Jurjen J. Luykx

Clozapine is highly effective for treatment-resistant schizophrenia but underutilized due to patient and clinician-related concerns. Little known about the general level of satisfaction with clozapine determinants thereof. We therefore explored in individuals diagnosed spectrum disorders (SSDs). Cross-sectional data from 480 users were used examine demographic clinical factors, including symptom severity, treatment response, adverse drug reactions (ADRs). Patient was self-rated on a scale 1...

10.1038/s41537-025-00570-9 article EN cc-by-nc-nd Schizophrenia 2025-02-23

Background 1 in 5 people with new HIV diagnoses are not linked to medical care after diagnosis. Persons who Black/African American, Hispanic/Latinx, young, and previously or currently use drugs via injection have low rates of linking care. We explored perceptions patients living about how social determinants health (SDoH) affect linkage Methods recruited from a large safety-net hospital Boston belonging one the groups high risk for conducted semi-structured interviews in-person...

10.21203/rs.3.rs-6534966/v1 preprint EN Research Square (Research Square) 2025-05-16

Delirium remains underdetected as a result of its broad constellation symptoms and the inadequate neuropsychiatric expertise most medical-surgical clinicians. Brief, accurate tools are needed to enhance detection.The authors extended validation Diagnostic Tool-Provisional (DDT-Pro), originally validated in study inpatients with traumatic brain injury for diagnosis delirium by nonexpert clinicians, 200 general medical Colombia. The three structured, quantitatively rated items DDT-Pro...

10.1176/appi.neuropsych.18110255 article EN Journal of Neuropsychiatry 2019-10-30

10.1016/j.oftale.2014.02.009 article ES Archivos de la Sociedad Española de Oftalmología (English Edition) 2014-09-01

Mild cognitive impairment (MCI) and dementia (DEM) are prevalent in skilled nursing facilities (SNFs), confounding delirium detection. We report characteristics of an SNF to ascertain distinguishing features for diagnosis, despite challenges comorbidity with MCI DEM.Cross-sectional study 200 consecutive patients from Catalunya, Spain, assessed within the first 24 48 admission hours by independent experts Spanish-Informant Questionnaire on Cognitive Decline Elderly (for MCI-DEM), Diagnostic...

10.1002/gps.5120 article EN International Journal of Geriatric Psychiatry 2019-04-16

For proper cholesterol metabolism, normal expression and function of scavenger receptor class B type I (SR-BI), a high-density lipoprotein (HDL) receptor, is required. Among the factors that regulate overall homeostasis HDL nuclear farnesoid X plays an important role. Guggulsterone, bioactive compound present in natural product gugulipid, antagonist this receptor. This widely used globally as lipid-lowering agent, although its anti-atherogenic cardiovascular benefit animal models or humans...

10.1371/journal.pone.0184280 article EN cc-by PLoS ONE 2017-09-14

10.1016/j.rpsmen.2015.10.002 article EN Revista de Psiquiatría y Salud Mental (English Edition) 2015-10-01

<title>Abstract</title> Introduction: The functional recovery of older adults in postacute care units is influenced by demographic and clinical factors, including the presence dementia. However, studies on this topic are scarce do not often focus population. Objective: objective was to determine influence different factors prognosis, mortality need for support at discharge patients admitted a centre, controlling Methods: We conducted prospective observational study. analysed correlations...

10.21203/rs.3.rs-4909925/v1 preprint EN Research Square (Research Square) 2024-09-12

Surface topography (ST) is a tool used to assess adolescent idiopathic scoliosis (AIS), which affects females more severely than males. However, current ST techniques fail measure breast asymmetry related torso deformity. Cosmetic deformity important patients because poor body appearance can cause psychological distress. Breast especially females. This study develops method for assessing using in with AIS, and proposes reliable classification such patients. To achieve this, scans of 25 (age:...

10.1186/1748-7161-8-s2-o39 article EN cc-by Scoliosis 2013-09-01
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