A5085660499- International Student and Expatriate Challenges
- Global Education and Multiculturalism
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Higher Education Governance and Development
- Adipose Tissue and Metabolism
- EFL/ESL Teaching and Learning
- Medical Research and Treatments
- Health and Wellbeing Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cytokine Signaling Pathways and Interactions
- Student Assessment and Feedback
- Second Language Learning and Teaching
- Lipid metabolism and biosynthesis
- Receptor Mechanisms and Signaling
- Higher Education and Teaching Methods
- Advanced Drug Delivery Systems
- Breastfeeding Practices and Influences
- Cultural Competency in Health Care
- Economics of Agriculture and Food Markets
- Educational Reforms and Innovations
- Sports Performance and Training
- Digital Media and Visual Art
- Mobile Health and mHealth Applications
- Mitochondrial Function and Pathology
Yale University
2025
Purdue University West Lafayette
2018-2024
Nanjing Agricultural University
2024
Google (United States)
2022-2023
Lafayette College
2020
Rensselaer Polytechnic Institute
2020
Swarthmore College
2020
University of California, San Francisco
2011-2017
Third Xiangya Hospital
2016
Central South University
2016
As a treatment for dyslipidemia, oral doses of 1–3 grams nicotinic acid per day lower serum triglycerides, raise high density lipoprotein cholesterol, and reduce mortality from coronary heart disease (Tavintharan, S., Kashyap, M. L. (2001) Curr. Atheroscler. Rep. 3, 74–82). These benefits likely result the ability to inhibit lipolysis in adipocytes thereby non-esterified fatty levels (Carlson, A. (1963) Acta Med. Scand. 173, 719–722). In mice, inhibits via PUMA-G, Gi/o-coupled...
Objective: The study identified important stressors associated with depressive symptoms in college students across the subgroups of gender and domestic/international status, compared between-group differences stress levels. Participants: Data were collected from 631 undergraduate October 2014 to March 2015. Methods: Participants completed an online survey containing measures (Student-Stress-Survey), (CES-D scale), demographics. Results: mean CES-D score (16.24) sample indicated high...
Dyneins are microtubule-based motor proteins that power ciliary beating, transport intracellular cargos, and help to construct the mitotic spindle. Evolved from ring-shaped hexameric AAA-family adenosine triphosphatases (ATPases), dynein's large size complexity have posed challenges for understanding its structure mechanism. Here, we present a 6 angstrom crystal of functional dimer two ~300-kilodalton domains yeast cytoplasmic dynein. The reveals an unusual asymmetric arrangement ATPase in...
GPR109A is not the target mediating niacin’s lipid efficacy and free fatty acid hypothesis does explain mechanism of action.
Heparin-binding epidermal growth factor (EGF)-like (HB-EGF) is found in cerebral neurons, and its expression increased after hypoxic or ischemic injury, which also stimulates neurogenesis. To investigate the possible role of HB-EGF hypoxic–ischemic induction neurogenesis, we measured expression, effects, target receptors embryonic murine cortical cultures adult rat brain. Hypoxia by ∼50% cultures, where was associated with mature immature neurons. (5–100 ng/ml) stimulated ∼80% incorporation...
Abstract Background Living–learning communities and global or diversity learning experiences have been identified as educational practices which often a “high impact” on student success, well providing interpersonal competencies that are greatly valued by employers. Even without specific intercultural component, living–learning would seem to offer rich settings for the development of ability work effectively across cultural difference. Yet outcomes rarely assessed outside domain study abroad...
In this case-control study, the main risk factors for atrophic gastritis (AG) were comprehensively analyzed in a real-world environment to identify potential associated with garlic intake and its effects on AG. Design Upper gastrointestinal endoscopy pathological examination performed as part of gastric cancer screening health check-up program. The detailed characteristics both case group healthy control recorded analyzed. All participants fasted at least 4 h urea breath test13C-UBT) was all...
Scholars suggest that study abroad programs must intentionally design and implement intercultural intervention for students’ growth. This used a mixed-method approach to examine the effectiveness of an online curriculum designed facilitate competence development semester students. Three theories informed curricular study: Intercultural Development Continuum, Praxis Model, Knowledge Competence VALUE rubric. Using Inventory (IDI) distributed before after experience, analyzed data sets...
This article examines the meanings, practices, and cultural beliefs underlying medication adherence in people of Chinese descent living United States. The narratives were analyzed using interpretive phenomenology, resulting following themes that influenced communication behaviors around participants: (a) concepts yin yang balance “qi,” (b) understandings Western medicine’s efficacy profiles, (c) importance family social support, (d) level acculturation. discusses influence these on proposes...
There is an inverse correlation between systemic blood pressure and urinary kallikrein levels in humans hypertensive animal models, suggesting that the tissue kallikrein-kinin system plays important role regulation. In this study, we explored potential of human gene delivery on reduction spontaneously rats (SHR). The or cDNA was placed under control following promoters: metallothionein metal response-element (MRE-pHK), albumin (ALB-pHK), Rous sarcoma virus 3′ long terminal repeat (LTR)...
Heparin-binding epidermal growth factor (EGF)-like (HB-EGF) stimulates cell proliferation in the adult mammalian brain, but mechanism involved is unknown. To address this issue we treated mouse brain cerebral cortical cultures enriched neuronal precursors with full-length HB-EGF, its HB or EGF-like domain alone, both domains combination. Labeling of bromodeoxyuridine (BrdU), a marker proliferation, was increased approximately 10% by and 20% domain, effects two were additive. Full-length...
Phenolic acids are found in abundance throughout the plant kingdom. Consumption of wine or other rich sources phenolic acids, such as "Mediterranean diet," has been associated with a lower risk cardiovascular disease. The underlying mechanism(s), however, remained unclear. Here, we show that many including those from hydroxybenzoic and hydroxycinnamic acid classes, can bind activate GPR109A (HM74a/PUMA-G), receptor for antidyslipidemic agent nicotinic acid. In keeping this activity,...
Tissue kallikrein has been shown to play a role in blood pressure regulation, and abnormalities the kallikrein-kinin system are considered be factor pathogenesis of hypertension. To elucidate potential therapeutic effects gene delivery hypertension, an adenoviral vector containing human tissue under control cytomegalovirus promoter, Ad.CMV-cHK, was intravenously injected into spontaneously hypertensive rats (SHR). A single injection Ad.CMV-cHK SHR caused sustained delay increase from day 2...
Purpose: Providing culturally responsive care for a diverse patient population is critical future speech-language pathologists and audiologists. Prior studies have shown gains in intercultural competence (ICC) from study abroad programs, face-to-face classes, online courses; however, limited investigated differences between modes of delivery pathology audiology. The purpose this was (a) to evaluate whether there are quantitative development ICC direct comparison 100% asynchronous...
Uncoupling protein 2 (UCP2) is a mitochondrial membrane that regulates energy metabolism and reactive oxygen species (ROS) production. We generated mouse carboxy- amino-terminal green fluorescent (GFP)-tagged UCP2 constructs to investigate the effect of expression on cell proliferation viability. UCP2-transfected Hepa 1-6 cells did not show reduced cellular adenosine triphosphate (ATP) but showed increased levels glutathione. Flow cytometry analysis indicated transfected were less...
High potassium intake is known to attenuate hypertension, glomerular lesion, ischemic damage, and stroke-associated death. Our recent studies showed that expression of recombinant kallikrein by somatic gene delivery reduced high blood pressure, cardiac hypertrophy, renal injury in hypertensive animal models. The aim this study explore the potential role tissue kallikrein-kinin system pressure reduction protection spontaneously rats (SHR) on a high-potassium diet. Young SHR were given...
Abstract Rice is the most important staple food in People's Republic of China (PRC). In many Asian countries rice appears to have become an inferior good, with income increases leading declines per capita consumption as other products are substituted for rice. this study, human analyzed a model that allows elasticities vary levels. An additional equation accounting disappearance seed, livestock feed, industrial uses and exports also estimated. The results analysis indicate has good likely...
Fatty liver or hepatic steatosis is a common health problem associated with abnormal function and increased susceptibility to ischemia/reperfusion injury. The objective of this study was investigate the effect fatty acid synthase inhibitor cerulenin on in steatotic ob/ob mice. Different dosages were administered intraperitoneally mice for 2 7 days. Body weight, serum AST/ALT, energy state, gene expression patterns examined. We found that treatment markedly improved Serum AST/ALT levels...