A5061483553- Chronic Kidney Disease and Diabetes
- Hormonal Regulation and Hypertension
- Acute Kidney Injury Research
- Diabetes Treatment and Management
- Adrenal and Paraganglionic Tumors
- Advanced Measurement and Metrology Techniques
- Adrenal Hormones and Disorders
- Advanced machining processes and optimization
- Parathyroid Disorders and Treatments
- COVID-19 Clinical Research Studies
- Renal and Vascular Pathologies
- SARS-CoV-2 and COVID-19 Research
- Sepsis Diagnosis and Treatment
- Genetic Syndromes and Imprinting
- Potassium and Related Disorders
- Advanced Numerical Analysis Techniques
- Advanced Surface Polishing Techniques
- Cardiac Arrest and Resuscitation
- Metabolism, Diabetes, and Cancer
- Dialysis and Renal Disease Management
- Heterotopic Ossification and Related Conditions
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Peroxisome Proliferator-Activated Receptors
- Vaccine Coverage and Hesitancy
- Vitamin D Research Studies
Wan Fang Hospital
2005-2025
Taipei Medical University
2005-2024
Mackay Memorial Hospital
2022
Taipei Institute of Pathology
2021
Hungkuang University
2018
Chiayi Chang Gung Memorial Hospital
2010-2016
Chang Gung University
2010-2016
University of California, Los Angeles
2010-2016
Medical University of South Carolina
2016
Chung Yuan Christian University
2004-2013
The clinical characteristics and outcomes in patients with aldosterone-producing adenomas harboring KCNJ5 mutations or without subclinical hypercortisolism remain unclear. This prospective study is aimed at determining factors associated adenomas. Totally, 82 were recruited from November 2016 to March 2018 underwent unilateral laparoscopic adrenalectomy least a 12-month follow-up postoperatively. Standard (defined as cortisol >1.8 μg/dL after 1 mg dexamethasone suppression test [DST]) was...
This study examined the involvement of fibroblast growth factor-23 (FGF-23) in primary aldosteronism (PA), a condition characterized by elevated aldosterone levels and hypertension. We recruited patients with unilateral PA (uPA) observed increased C-terminal FGF-23 (cFGF-23) to intact (iFGF-23) uPA compared essential hypertension control participants. Elevated preoperative cFGF-23 were associated adverse outcomes, including mortality cardiovascular or kidney events. Plasma demonstrated...
Chronic kidney disease–mineral bone disorder (CKD–MBD), comprising mineral, hormonal, and metabolic imbalance, is a major CKD-related issue; it causes osteoporosis prevalence in CKD patients. Osteocyte-derived sclerostin inhibits the osteogenic Wnt/β-catenin signaling pathway; its levels rise when function declines. Exercise modulates physiological functions of osteocytes, potentially altering production. It may aid mineral electrolyte homeostasis CKD. Mild was induced rats by partial...
Chronic kidney disease (CKD) patients tend to have a reduced immune response infection and vaccination. The efficacy of current available COVID-19 vaccines in CKD has not been widely evaluated.In the present study, three hundred eight chronic dialysis received ChAdOx1 nCoV-19 (Oxford-AstraZeneca, AZ). Blood tests using an antibody against receptor-binding domain (RBD) S1 subunit SARS-CoV-2 spike protein had performed at four designed time points before after first second vaccine.The mean age...
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Abstract Context Patients with diabetes are prone to acute kidney injury the potential transition chronic disease. Few studies have investigated role of thiazolidinedione (TZD) in these patients under disease (AKD) phase. Objective We sought examine whether using TZD during AKD could reduce risk future major adverse outcomes. Design and Methods employed TriNetX platform before September 30, 2022, for administration type 2 mellitus (T2DM) within 90 days an diagnosis. Clinical endpoints...
A 50-year-old male presented with fever and anorexia of 2 days’ duration a 3-week history abdominal fullness. Two years earlier, he had left-sided acute pyelonephritis, incomplete duplicated ureters ureteral stone. The stone was removed. He also hypertension, gout, chronic renal failure serum creatinine 3.1mg/dl. Examination the abdomen revealed palpable mass tenderness at left upper quadrant. Investigations showed white blood cell count 21190 cells/mm, urea nitrogen 84mg/dl, 5.4mg/dl,...
Background Phosphate burden in chronic kidney disease (CKD) leads to elevated serum fibroblast factor-23 (FGF-23) levels, secondary hyperparathyroidism and disease-mineral bone disorder (CKD-MBD). However dissociated hyperphosphatemia low FGF-23 concentrations have been observed experimentally parathyoridectomized rats. The relationships between mineral, hormone, metabolism may be altered the presence of CKD. aim our study was investigate whether a consistent relationship existed specific...
Non-classical multiple aldosterone-producing micronodules/nodules (mAPM/mAPN) could be the pathogenesis of primary aldosteronism (PA). The co-existence mAPM with adenomas harboring somatic mutations has not previously been reported.We presented a PA patient bilateral and concomitant autonomous cortisol secretion (ACS).A 46-year-old Taiwanese woman hypertension, hypokalemia, adrenal adenomas. A 1 mg low-dose dexamethasone suppression test showed elevated morning serum cortisol. An vein...