A5005066427- SARS-CoV-2 and COVID-19 Research
- Dialysis and Renal Disease Management
- COVID-19 Clinical Research Studies
- Radiology practices and education
- Innovations in Medical Education
- Diabetes Treatment and Management
- Chronic Kidney Disease and Diabetes
- Microbial metabolism and enzyme function
- Urological Disorders and Treatments
- Hormonal Regulation and Hypertension
- Complement system in diseases
- Vaccine Coverage and Hesitancy
- Bone and Joint Diseases
- Monoclonal and Polyclonal Antibodies Research
- Healthcare cost, quality, practices
- Drug-Induced Hepatotoxicity and Protection
- Dietary Effects on Health
- Pharmacological Effects and Toxicity Studies
- Seaweed-derived Bioactive Compounds
- Advanced Glycation End Products research
- Ureteral procedures and complications
- Renal Diseases and Glomerulopathies
- Aortic Thrombus and Embolism
- Social Media in Health Education
- Nitric Oxide and Endothelin Effects
Taipei Medical University
2011-2024
Wan Fang Hospital
2011-2024
Royal Women's Hospital
2024
Abstract Tubulointerstitial fibrosis is recognized as a key determinant of progressive chronic kidney disease (CKD). Fucoidan, sulphated polysaccharide extracted from brown seaweed, exerts beneficial effects in some nephropathy models. The present study evaluated the inhibitory effect oligo-fucoidan (800 Da) on renal tubulointerstitial fibrosis. We established mouse CKD model by right nephrectomy with transient ischemic injury to left kidney. Six weeks after surgery, we fed mice at 10, 20,...
Abstract Background As ultrasound has become increasingly prominent in medicine, portable is perceived as the visual stethoscope of twenty-first century. Many studies have shown that exposing preclinical students to training can increase their motivation and competency. However, few discussed effect on anatomy learning. Method The Parallel Ultrasound Hands-on (PUSH) course was designed investigate whether or not ultrasonography affects knowledge acquisition. PUSH included anatomical...
We report two patients with drug‐induced liver injury (DILI)‐related acute failure (ALF) who were successfully treated high‐volume plasma exchange without transplantation. The first patient was a 66‐year‐old man admitted because of perforated duodenal ulcer complicated peritonitis and septic shock. After treatment multiple antibiotics, the developed DILI ALF. Grade 3 hepatic encephalopathy profound jaundice present. Symptoms signs ALF improved dramatically after initiation exchange....
Chronic kidney disease (CKD) patients tend to have a reduced immune response infection and vaccination. The efficacy of current available COVID-19 vaccines in CKD has not been widely evaluated.In the present study, three hundred eight chronic dialysis received ChAdOx1 nCoV-19 (Oxford-AstraZeneca, AZ). Blood tests using an antibody against receptor-binding domain (RBD) S1 subunit SARS-CoV-2 spike protein had performed at four designed time points before after first second vaccine.The mean age...
Acute kidney injury (AKI) is a sudden episode of damage that commonly occurs in patients admitted to hospitals. To date, no ideal treatment has been developed reduce AKI severity. Oligo-fucoidan (FC) interferes with renal tubular cell surface protein cluster differentiation 44 (CD44) prevent interstitial fibrosis; however, the influence oligosaccharides on remains unknown. In this study, FC, galacto-oligosaccharide (GOS), and fructo-oligosaccharide (FOS) were selected investigate AKI. All...
ABSTRACT Background Dipeptidyl peptidase 4 inhibitors (DPP4is) are considered safe for use in patients with diabetes mellitus and kidney dysfunction. We explored whether usage of DPP4is who recovered from dialysis-requiring acute injury (AKI) could reduce the risk future cardiac events. Methods used TriNetX platform to investigate within 90 days discharge disease all-cause mortality, major adverse events (MAKEs), cardiovascular (MACEs), re-dialysis. The were followed 5 years or until...
The role of the hepato-protective agent plasmon-activated water (PAW) as an innovative anti-oxidant during chronic sleep deprivation (SD) is realized in this study. PAW possesses reduced hydrogen-bonded structure, higher chemical potential and significant anti-oxidative properties. In vitro tests using rat liver cell line (Clone-9) have demonstrated that non-cytotoxic does not change cellular migration capacity. vivo experiment on SD rats suffering from intense oxidative damage to liver,...
The intimate correlation of chronic kidney disease (CKD) with structural alteration in gut microbiota or metabolite profile has been documented a growing body studies. Nevertheless, paucity demonstrated knowledge regarding the impact and underlying mechanism on occurrence progression CKD is unclarified thus far. In this study, liquid chromatography coupled-mass spectrometry long-read sequencing were applied to identify metabolites microbiome statistically-discriminative abundance diabetic...
Abstract Agranulocytosis is an uncommon but serious complication of Graves' disease under thionamide therapy. In some patients removal circulating thyroid hormones and antibodies by plasmapheresis effective adjunctive therapeutic option. perioperative settings, however, may cause excess bleeding intraoperatively due to coagulation factor depletion unless fresh frozen plasma (FFP) products are used in the replacement fluid mix. Double filtration (DFPP) which only a small amount albumin...
The clinical characteristics and surgical prognosis of glucocorticoid-remediable aldosteronism (GRA, also known as familial hyperaldosteronism type 1, FH-I) have not been widely studied. Using data from the Taiwan Primary Aldosteronism Investigation (TAIPAI) registry retrospectively, we describe associated factors for GRA predictors outcomes among identified patients. We found 79 GRA-positive (51.2 ± 13.8 years; women 39 (49.4%)) 114 GRA-negative primary (PA) patients matched with age,...
Objectives Numerous factors are associated with the risk of osteoporosis in patients chronic kidney disease, including vitamin D deficiency, hypocalcaemia, hyperphosphataemia and secondary hyperparathyroidism. This study aimed to assess correlation between cumulative erythropoietin (EPO) doses on dialysis. A further objective was determine bone mineral density (BMD) undergoing dialysis its specific clinical biochemical factors. Setting The undertaken at a tertiary care centre within southern...
Severe falciparum malaria is associated with multiple organ dysfunction and a high rate of fatal outcome. Malaria world-wide disease in tropical areas through the bites vector mosquitoes. Parasitic protozoans introduced by mosquito's saliva to blood travel liver then mature reproduce. In humans, caused Plasmodium falciparum, P. malariae, ovale, vivax, knowlesi, causes most deaths. Typical symptoms include fever, chills, fatigue, headache, nausea, vomiting. severe cases, it can cause...
Abstract Background Point-of-care ultrasound (POCUS) has become a hot issue and trend in medical education recent years. Ultrasound is an indispensable skill for clinical physicians. Previous studies have already discussed the importance of advancements education. However, learning motivations with regard to seldom been literature. For students, could strong connection their future career. ERG theory extended Maslow's hierarchy needs through concepts existence, relatedness, growth. The...
Over the past two decades, debates on whether profit status of dialysis facilities influences patient prognosis have been popular in USA. Taiwan is one regions with highest rate per capita kidney replacement therapy worldwide, but no similar research has conducted to date. This first study address this issue. was a nationwide retrospective cohort based Renal Registry Data System. Patients were categorised into groups (for-profit, not-for-profit (NFP)) facilities, 31 350 patients each group....
Background: Hemodialysis patients are at an increased risk of SARS-CoV-2 infection and excluded from preauthorization COVID-19 vaccine trials; therefore, their immunogenicity is uncertain. Methods: To compare the antibody responses to homologous ChAdOx1 mRNA-1273 vaccination in hemodialysis patients, 103 age- sex-matched with two prime-boost vaccinations were recruited detect anti-receptor-binding domain (RBD) IgG levels seroconversion rates (SCRs) 14 days after a prime dose (PD14), before...
Chronic kidney disease (CKD) poses a significant global health challenge, necessitating effective renal replacement therapies. Peritoneal dialysis (PD) offers patient-friendly, home-based alternative to hemodialysis. The Stepwise Initiation of Dialysis (SIPD) method, used in the SPD group and involving gradual introduction PD, presents potential advantage over traditional protocols, yet scientific literature on its efficacy safety is limited.
Background and Objectives: Osteoporosis anemia are prevalent among chronic kidney disease stage 5D (CKD 5D) patients. Osteoblasts known as the niche cells of hematopoietic stem (HSCs) stimulate HSCs to form blood-cell lineages within bone marrow microenvironments. We hypothesized that an inverse correlation may exist between mean corpuscular volume (MCV), a surrogate for ineffective hematopoiesis, mineral density (BMD) in CKD population. Materials Methods: This is cross-sectional designed...
Unilateral kidney hypoplasia is a congenital condition characterized by the underdevelopment of one kidney. Although often asymptomatic, it can cause severe renal complications in patients combined with contralateral injury, leading to acute failure. This case report describes patient unilateral who underwent biopsy on normal-sized and subsequently developed oliguric injury. discusses challenges encountered while diagnosing managing this rare case, highlighting importance awareness...
<title>Abstract</title> <bold>Background</bold> Acquiring proficiency in medicine typically necessitates a combination of foundational knowledge and hands-on experience. However, how do lecture practice affect the psychological learning process ultrasound education remains unclear. The purpose this research was to test different activities associated with psychomotor domain, elucidating their connections cognitive affective domains context education. <bold>Method</bold> This study is...