A5107093633- Aquaculture disease management and microbiota
- Antimicrobial Peptides and Activities
- Tree-ring climate responses
- Invertebrate Immune Response Mechanisms
- Protein Hydrolysis and Bioactive Peptides
- Aquaculture Nutrition and Growth
- Plant Water Relations and Carbon Dynamics
- Physiological and biochemical adaptations
- Ovarian function and disorders
- Reproductive Biology and Fertility
- Environmental and Cultural Studies in Latin America and Beyond
- Endometriosis Research and Treatment
- Climate variability and models
- Reproductive System and Pregnancy
- Immune Cell Function and Interaction
- Chemical Synthesis and Analysis
- Fish Ecology and Management Studies
- Iron Metabolism and Disorders
- Advanced biosensing and bioanalysis techniques
- Biochemical and Structural Characterization
- Regulation of Appetite and Obesity
- Computational Drug Discovery Methods
- Probiotics and Fermented Foods
- Ovarian cancer diagnosis and treatment
- Trace Elements in Health
Universidad Católica del Norte
2018-2024
Centro de Recursos Educativos Avanzados
2018-2024
Instituto de Estudios Avanzados
2024
Centro de Estudios Científicos
2024
Austral University of Chile
2009-2023
Center for Climate and Resilience Research
2022-2023
Interdisciplinary Center for Aquaculture Research
2023
Pontificia Universidad Católica de Valparaíso
2013-2018
University of Chile
2017
Federico Santa María Technical University
2014-2016
Significance The SADA is an annually-resolved hydroclimate atlas in South America that spans the continent south of 12°S from 1400 to 2000 CE. Based on 286 tree ring records and instrumentally-based estimates soil moisture, complements six drought atlases worldwide filling a geographical gap Southern Hemisphere. Independently validated with historical records, shows frequency widespread severe droughts extreme pluvials since 1960s unprecedented. Major events expressed are associated strong...
Ovarian hyperstimulation syndrome (OHSS) results from increased vascular permeability (VP) caused by ovarian hypersecretion of endothelial growth factor (VEGF), which activates its receptor-2. In animals, the dopamine receptor 2 agonist cabergoline (Cb2) inactivates VEGF receptor-2 and prevents VP.Our objective was to test whether Cb2 reduces VP OHSS in humans.We conducted a prospective, randomized, double-blind study on oocyte donors at risk developing (>20 follicles, >12 mm developed, >20...
Abstract. Throughout the second half of 20th century, Central Andes has experienced significant climatic and environmental changes characterized by a persistent warming trend, an increase in elevation 0 °C isotherm, sustained glacier shrinkage. These have occurred conjunction with steadily growing demand for water resources. Given short span instrumental hydroclimatic records this region, longer time are needed to understand nature climate variability improve predictability precipitation,...
The outburst of microbial resistance to antibiotics creates the need for new sources active compounds treatment pathogenic microorganisms. Marine microalgae are particular interest in this context because they have developed tolerance and defense strategies resist exposure bacteria, viruses, fungi aquatic environment. Although antimicrobial activities been reported some microalgae, natural algal bioactive peptides not described yet. In work, acid extracts from microalga Tetraselmis suecica...
Antimicrobial peptides (AMP) play an essential role in the innate immune system, modulating defense response. In a previous study, we demonstrated antimicrobial activity of synthetic hepcidin (hep20) from rainbow trout (Oncorhynchus mykiss), and its protective effect European sea bass (Dicentrarchus labrax) challenged with Vibrio anguillarum. Additionally, described uptake distribution hep20 different tissues leukocyte cells. Interestingly, various AMPs characterized high vertebrates, called...
Tree growth is generally considered to be temperature limited at upper elevation treelines, yet climate factors controlling tree semiarid treelines are poorly understood. We explored the influence of on stem and stable isotopes for Polylepis tarapacana Philipi, world's highest species, which found only in South American Altiplano. developed tree-ring width index (RWI), oxygen (δ18O) carbon (δ13C) chronologies last 60 years four P. stands located above 4400 m elevation, along a 500 km...
Abstract. Given the short span of instrumental precipitation records in South American Altiplano, longer-term hydroclimatic are needed to understand nature climate variability and improve predictability precipitation, a key natural resource for socioeconomic development Altiplano adjacent arid lowlands. In this region grows Polylepis tarapacana, long-lived tree species that is very sensitive changes has been widely used tree-ring studies central southern Altiplano. However, northern sector...
Piscirickettsia salmonis is a facultative intracellular bacterium that causes the disease called "salmon rickettsial syndrome". Attempts to control this have been unsuccessful, because existing vaccines not achieved expected effectiveness and antibiotics used fail completely eradicate pathogen. This in part product of lack scientific information still lacks on mechanisms by overcome infected–cell responses survive induce productive infection macrophages. For that, work was focused...
Peptide synthesis is an area with a wide field of application, from biomedicine to nanotechnology, that offers the option simultaneously synthesizing large number sequences for purpose preliminary screening, which powerful tool. Nevertheless, standard protocols generate volumes solvent waste. Here, we present protocol multiple Fmoc solid-phase peptide in tea bags, where reagent recycling steps are included. Fifty-two peptides amino acid composition and seven twenty residues length were...
Abstract BACKGROUND Oxidative reactions are responsible for the changes in quality during food processing and storage. stress is also involved multiple chronic diseases, such as cardiovascular neurodegenerative disorders, diabetes, cancer, aging. The consumption of dietary antioxidants has been demonstrated to help reduce oxidative damage both human body systems. In this study, potential Erythrina edulis (pajuro) protein source antioxidant peptides was evaluated. RESULTS Pajuro concentrate...
The elder (Sambucus spp.) tree has a number of uses in traditional medicine. Previous studies have demonstrated the antimicrobial properties elderberry liquid extract against human pathogenic bacteria and also influenza viruses. These been mainly attributed to phenolic compounds. However, other plant defense molecules, such as peptides (AMPs), may be present. Here, we studied peptide extracts from flowers Sambucus nigra L. mass spectrometry analyses determined 3 3.6 kDa, among them,...
Currently, one of the primary challenges in salmon farming is caligidosis, caused by copepod ectoparasites Caligus spp. The infection process determined copepod’s ability to adhere fish skin through insertion its chitin-composed filament. In this study, we examined several antimicrobial peptides previously identified salmonid mucosal secretions, with a focus on their potential bind chitin as an initial step. binding capacity was tested, hepcidin and piscidin showing positive results. Further...