Claudio A. Álvarez

ORCID: 0000-0003-3132-2187
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Aquaculture disease management and microbiota
  • Antimicrobial Peptides and Activities
  • Tree-ring climate responses
  • Invertebrate Immune Response Mechanisms
  • Protein Hydrolysis and Bioactive Peptides
  • Aquaculture Nutrition and Growth
  • Plant Water Relations and Carbon Dynamics
  • Physiological and biochemical adaptations
  • Ovarian function and disorders
  • Reproductive Biology and Fertility
  • Environmental and Cultural Studies in Latin America and Beyond
  • Endometriosis Research and Treatment
  • Climate variability and models
  • Reproductive System and Pregnancy
  • Immune Cell Function and Interaction
  • Chemical Synthesis and Analysis
  • Fish Ecology and Management Studies
  • Iron Metabolism and Disorders
  • Advanced biosensing and bioanalysis techniques
  • Biochemical and Structural Characterization
  • Regulation of Appetite and Obesity
  • Computational Drug Discovery Methods
  • Probiotics and Fermented Foods
  • Ovarian cancer diagnosis and treatment
  • Trace Elements in Health

Universidad Católica del Norte
2018-2024

Centro de Recursos Educativos Avanzados
2018-2024

Instituto de Estudios Avanzados
2024

Centro de Estudios Científicos
2024

Austral University of Chile
2009-2023

Center for Climate and Resilience Research
2022-2023

Interdisciplinary Center for Aquaculture Research
2023

Pontificia Universidad Católica de Valparaíso
2013-2018

University of Chile
2017

Federico Santa María Technical University
2014-2016

Significance The SADA is an annually-resolved hydroclimate atlas in South America that spans the continent south of 12°S from 1400 to 2000 CE. Based on 286 tree ring records and instrumentally-based estimates soil moisture, complements six drought atlases worldwide filling a geographical gap Southern Hemisphere. Independently validated with historical records, shows frequency widespread severe droughts extreme pluvials since 1960s unprecedented. Major events expressed are associated strong...

10.1073/pnas.2002411117 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2020-07-06

Ovarian hyperstimulation syndrome (OHSS) results from increased vascular permeability (VP) caused by ovarian hypersecretion of endothelial growth factor (VEGF), which activates its receptor-2. In animals, the dopamine receptor 2 agonist cabergoline (Cb2) inactivates VEGF receptor-2 and prevents VP.Our objective was to test whether Cb2 reduces VP OHSS in humans.We conducted a prospective, randomized, double-blind study on oocyte donors at risk developing (>20 follicles, >12 mm developed, >20...

10.1210/jc.2007-0409 article EN The Journal of Clinical Endocrinology & Metabolism 2007-04-25

Abstract. Throughout the second half of 20th century, Central Andes has experienced significant climatic and environmental changes characterized by a persistent warming trend, an increase in elevation 0 °C isotherm, sustained glacier shrinkage. These have occurred conjunction with steadily growing demand for water resources. Given short span instrumental hydroclimatic records this region, longer time are needed to understand nature climate variability improve predictability precipitation,...

10.5194/cp-8-653-2012 article EN cc-by Climate of the past 2012-03-30

The outburst of microbial resistance to antibiotics creates the need for new sources active compounds treatment pathogenic microorganisms. Marine microalgae are particular interest in this context because they have developed tolerance and defense strategies resist exposure bacteria, viruses, fungi aquatic environment. Although antimicrobial activities been reported some microalgae, natural algal bioactive peptides not described yet. In work, acid extracts from microalga Tetraselmis suecica...

10.3390/md17080453 article EN cc-by Marine Drugs 2019-08-01

Antimicrobial peptides (AMP) play an essential role in the innate immune system, modulating defense response. In a previous study, we demonstrated antimicrobial activity of synthetic hepcidin (hep20) from rainbow trout (Oncorhynchus mykiss), and its protective effect European sea bass (Dicentrarchus labrax) challenged with Vibrio anguillarum. Additionally, described uptake distribution hep20 different tissues leukocyte cells. Interestingly, various AMPs characterized high vertebrates, called...

10.3390/ani12121586 article EN cc-by Animals 2022-06-20

Tree growth is generally considered to be temperature limited at upper elevation treelines, yet climate factors controlling tree semiarid treelines are poorly understood. We explored the influence of on stem and stable isotopes for Polylepis tarapacana Philipi, world's highest species, which found only in South American Altiplano. developed tree-ring width index (RWI), oxygen (δ18O) carbon (δ13C) chronologies last 60 years four P. stands located above 4400 m elevation, along a 500 km...

10.1093/treephys/tpab021 article EN Tree Physiology 2021-02-05

Abstract. Given the short span of instrumental precipitation records in South American Altiplano, longer-term hydroclimatic are needed to understand nature climate variability and improve predictability precipitation, a key natural resource for socioeconomic development Altiplano adjacent arid lowlands. In this region grows Polylepis tarapacana, long-lived tree species that is very sensitive changes has been widely used tree-ring studies central southern Altiplano. However, northern sector...

10.5194/cp-19-457-2023 article EN cc-by Climate of the past 2023-02-20

Piscirickettsia salmonis is a facultative intracellular bacterium that causes the disease called "salmon rickettsial syndrome". Attempts to control this have been unsuccessful, because existing vaccines not achieved expected effectiveness and antibiotics used fail completely eradicate pathogen. This in part product of lack scientific information still lacks on mechanisms by overcome infected–cell responses survive induce productive infection macrophages. For that, work was focused...

10.1371/journal.pone.0163943 article EN cc-by PLoS ONE 2016-10-10

Peptide synthesis is an area with a wide field of application, from biomedicine to nanotechnology, that offers the option simultaneously synthesizing large number sequences for purpose preliminary screening, which powerful tool. Nevertheless, standard protocols generate volumes solvent waste. Here, we present protocol multiple Fmoc solid-phase peptide in tea bags, where reagent recycling steps are included. Fifty-two peptides amino acid composition and seven twenty residues length were...

10.3390/molecules26165035 article EN cc-by Molecules 2021-08-19

Abstract BACKGROUND Oxidative reactions are responsible for the changes in quality during food processing and storage. stress is also involved multiple chronic diseases, such as cardiovascular neurodegenerative disorders, diabetes, cancer, aging. The consumption of dietary antioxidants has been demonstrated to help reduce oxidative damage both human body systems. In this study, potential Erythrina edulis (pajuro) protein source antioxidant peptides was evaluated. RESULTS Pajuro concentrate...

10.1002/jsfa.9449 article EN Journal of the Science of Food and Agriculture 2018-10-26

The elder (Sambucus spp.) tree has a number of uses in traditional medicine. Previous studies have demonstrated the antimicrobial properties elderberry liquid extract against human pathogenic bacteria and also influenza viruses. These been mainly attributed to phenolic compounds. However, other plant defense molecules, such as peptides (AMPs), may be present. Here, we studied peptide extracts from flowers Sambucus nigra L. mass spectrometry analyses determined 3 3.6 kDa, among them,...

10.3390/molecules23051033 article EN cc-by Molecules 2018-04-27

Currently, one of the primary challenges in salmon farming is caligidosis, caused by copepod ectoparasites Caligus spp. The infection process determined copepod’s ability to adhere fish skin through insertion its chitin-composed filament. In this study, we examined several antimicrobial peptides previously identified salmonid mucosal secretions, with a focus on their potential bind chitin as an initial step. binding capacity was tested, hepcidin and piscidin showing positive results. Further...

10.3390/pharmaceutics16030378 article EN cc-by Pharmaceutics 2024-03-08
Erich Gnaiger Eleonor Aasander Frostner Norwahidah Abdul Karim Nada A. Abumrad Darı́o Acuña-Castroviejo and 95 more Reginald Adiele Bumsoo Ahn Mayke Bezerra Alencar Sameh S. Ali Lesley A. Alton Marco Túlio Santana Alves Francesca Amati Nívea Dias Amoêdo Ioanna Andreadou Marc Arago Cenk Aral Odeta Arandarčikaitė Anne‐Sophie Armand Thierry Arnould Vlad Florian Avram Damian M. Bailey Sudip Bajpeyi Martina Bajzíková Barbara M. Bakker Jonathan Barlow A Banni a Yasseen Basma Ana Carolina Bastos Sant'Anna Silva Philip M. Batterson Maurizio Battino Jason N. Bazil Daniel Beard Piotr Bednarczyk Fiona Bello Dorit Ben‐Shachar Andreas Bergdahl Rolf K. Berge Lisa Bergmeister Paolo Bernardi Michael V. Berridge Stefano Bettinazzi David J. Bishop Pierre Blier Dan Filip Blindheim Neoma T. Boardman Hans Erik Boetker Sabine Borchard Mihály Boros Elisabet Børsheim Vilma Borutaite Javier Botella Frédéric Bouillaud Jamal Bouitbir Robert Boushel Josh Bovard Sophie Breton David Brown Guy J. Brown Robert N. Brown Joseph T. Brozinick Garry R. Buettner Johannes Burtscher Elisa Calabria José A. L. Calbet Enrico Calzia Daniel E. Cannon Maria Cano Sanchez Claudio A. Álvarez Daniele A. Cardinale Luiza H.D. Cardoso Eugénia Carvalho Marta Casado Pinna Samantha Cassar Maria Helane Costa Gurgel Castelo Laura Castro João Paulo Cavalcanti‐de‐Albuquerque Zuzana Červinková Béatrice Chabi Lisa Chakrabarti Sasanka Chakrabarti Bhagirath Chaurasia Qi Chen Adam J. Chicco Christos Chinopoulos Subir Roy Chowdhury Beáta Čižmárová Emilio Clementi Paul M. Coen Bruce S. Cohen Robert Coker Anne Collin Mt Coughlan Luís Crisóstomo Norma Dahdah Louise T. Dalgaard Maija Dambrova Tereza Daňhelovská Charles Darveau Anibh M. Das Ranjan Dash

10.26124/mitofit:190001.v6 preprint EN other-oa 2025-01-27
Coming Soon ...