A5071538921- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Electroconvulsive Therapy Studies
- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Memory and Neural Mechanisms
- Treatment of Major Depression
- Neural and Behavioral Psychology Studies
- Memory Processes and Influences
- Stress Responses and Cortisol
- Child and Adolescent Psychosocial and Emotional Development
- Neural dynamics and brain function
- Tryptophan and brain disorders
- Advanced Neuroimaging Techniques and Applications
- Autism Spectrum Disorder Research
- Bipolar Disorder and Treatment
- Neurological disorders and treatments
- Neuroscience and Neuropharmacology Research
- Attention Deficit Hyperactivity Disorder
- Schizophrenia research and treatment
- Neurobiology of Language and Bilingualism
- COVID-19 and Mental Health
- Advanced MRI Techniques and Applications
- Dementia and Cognitive Impairment Research
- EEG and Brain-Computer Interfaces
Radboud University Nijmegen
2016-2025
Radboud University Medical Center
2016-2025
Essen University Hospital
2015-2025
Pro Persona
2024-2025
University Medical Center
2012-2024
University of Duisburg-Essen
2011-2024
Trimbos Institute
2024
GGZ inGeest
2024
St. Antonius Ziekenhuis
2024
Brainclinics
2024
Retrieval of recently acquired declarative memories depends on the hippocampus, but with time, retrieval is increasingly sustainable by neocortical representations alone. This process has been conceptualized as system-level consolidation. Using functional magnetic resonance imaging, we assessed over course three months how consolidation affects neural correlates memory retrieval. The duration slow-wave sleep during a nap/rest period after initial study session and before first scan day 1...
Although repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for depression, little known about the comparative effectiveness of rTMS and other options, such as antidepressants. In this multicenter randomized controlled trial, was compared with next pharmacological step in patients treatment-resistant depression.
The medial temporal lobe (MTL) is essential for episodic memory encoding, as evidenced by deficits in patients with MTL damage. However, previous functional neuroimaging studies have either failed to show activation during encoding or they did not differentiate between two related processes: novelty assessment and encoding. Furthermore, there evidence that the can be subdivided into subcomponents serving different processes, but extent of this subdivision remains unknown. aim present...
<b><i>Background: </i></b> fMRI is becoming a standard tool for the presurgical lateralization and mapping of brain areas involved in language processing. However, its within-subject reproducibility has yet to be fully explored. <b><i>Objective: To evaluate within-test test–retest reliability consecutive patients undergoing evaluation epilepsy surgery. <b><i>Methods: Thirty-four unselected were investigated once (within-test reliability) 12 twice (test–retest reliability). The imaging series...
In rodents, cyclically fluctuating levels of gonadal steroid hormones modulate neural plasticity by altering synaptic transmission and synaptogenesis. Alterations mood cognition observed during the menstrual cycle suggest that steroid-related also occurs in humans. Cycle phase-dependent differences cognitive performance have almost exclusively been found tasks probing lateralized neuronal domains, i.e., domains such as language, which are predominantly executed one hemisphere. To search for...
Abstract Background Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans of elderly people related to vascular risk factors cognitive motor impairment, ultimately leading dementia or parkinsonism in some. In general, the relations are weak, not all subjects with SVD become demented get parkinsonism. This might be explained by diversity underlying pathology both white matter lesions (WML) normal appearing (NAWM). Both cannot properly appreciated conventional MRI....
The ability to temporarily prioritize rapid and vigilant reactions over slower higher-order cognitive functions is essential for adaptive responding threat. This reprioritization believed reflect shifts in resource allocation between large-scale brain networks that support these functions, including the salience executive control networks. However, how changes communication within such dynamically unfold as a function of threat-related arousal remains unknown. To address this issue, we...
Impaired mood regulation is a key deficit of major depressive disorder that primarily mediated by an interaction between the paralimbic cortex (i.e., orbitofrontal, cingulate, insular, parahippocampal, and temporopolar cortices) limbic regions. The authors investigated whether depressed patients healthy comparison subjects have differences in cortical thickness potential are evident only during state or trait related.Forty with first episode participated: 20 medication-naive currently...
BackgroundElectroconvulsive therapy (ECT) is associated with volumetric enlargements of corticolimbic brain regions. However, the pattern whole-brain structural alterations following ECT remains unresolved. Here, we examined longitudinal effects on global and local variations in gray matter, white ventricle volumes patients major depressive disorder as well predictors ECT-related clinical response.MethodsLongitudinal magnetic resonance imaging data from Global ECT-MRI Research Collaboration...
Abstract Background Anhedonia is apparent in different mental disorders and suggested to be related dysfunctions the reward system and/or affect regulation. It may hence a common underlying feature associated with symptom severity of disorders. Methods We constructed cross-sectional graphical Least Absolute Shrinkage Selection Operator (LASSO) network relative importance estimate relationships between anhedonia clusters major depressive disorder (MDD), anxiety sensitivity (AS),...
Electroconvulsive therapy (ECT) is a highly effective treatment for major depressive episodes (MDE). However, ECT-induced cognitive side-effects remain concern. Identification of pre-treatment predictors that contribute to these unclear. We examined performance and individual profiles over time (up six months) following ECT investigated possible clinical demographic decline shortly after ECT. 634 patients with MDE from five sites were included recruitment periods between 2001 2020. Linear...
Evidence from neurobiological studies suggests that schizophrenia arises an early abnormality in brain development and possibly further progressive developmental mechanisms. Despite a delay between the acquisition of neuropathology triggering psychosis, susceptibility is likely to be expressed subclinically by biobehavioral markers premorbid stage. The exploratory study aims at identifying potential neurocognitive risk factors investigating unfolding illness within cross-sectional design...