A5052937912- Pelvic floor disorders treatments
- Supercapacitor Materials and Fabrication
- Advancements in Battery Materials
- Advanced battery technologies research
- Cancer-related molecular mechanisms research
- Advanced Wireless Communication Technologies
- Advanced MIMO Systems Optimization
- Hernia repair and management
- Energy Harvesting in Wireless Networks
- Wireless Communication Security Techniques
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Epigenetics and DNA Methylation
- Autoimmune Neurological Disorders and Treatments
- Cervical Cancer and HPV Research
- Body Composition Measurement Techniques
- Nutrition and Health in Aging
- RNA regulation and disease
- Sexual function and dysfunction studies
- Pelvic and Acetabular Injuries
- Circular RNAs in diseases
- COVID-19 diagnosis using AI
- Liver Disease Diagnosis and Treatment
- MicroRNA in disease regulation
- RNA modifications and cancer
Sichuan University
2015-2025
West China Second University Hospital of Sichuan University
2010-2025
Beijing Tian Tan Hospital
2023-2025
Capital Medical University
2015-2025
Hebei North University
2025
University of Chinese Academy of Sciences
2017-2024
Yangzhou University
2024
Kai Biotech (South Korea)
2024
Guangzhou University
2022-2023
Cangzhou Central Hospital
2016-2023
Retinitis pigmentosa (RP) is an inherited retinal neurodegenerative disease which a significant contributor to blindness. Microglia-mediated inflammation plays crucial role in retinitis pigmentosa. However, the activation mechanisms of microglia and polarized RP remain unclear. High-mobility group box 1 (HMGB1) key aseptic inflammation, glycyrrhizin exerts anti-inflammatory effects by targeting HMGB1. This study aimed investigate HMGB1 explore protective on photoreceptors. Male C57BL/6 mice...
Abstract Due to its low latency and energy consumption, edge computing technology is essential in processing multi-source data streams from intelligent devices. This article investigates a mobile network aided by wireless power transfer (WPT) for streams, where the channel parameters characteristic of stream are varied. Moreover, we consider practical communication scenario, devices with limited battery capacity cannot support executing transmitting computational under given latency. Thus,...
Heavy-ion beam irradiation is one of the principal methods used to create mutants in plants. Research on mutagenic effects and molecular mechanisms radiation an important subject that multi-disciplinary. Here, we re-sequenced 11 mutagenesis progeny (M3) Arabidopsis thaliana lines derived from carbon-ion (CIB) irradiation, subsequently focused substitutions small insertion-deletion (INDELs). We found CIB induced more (320) than INDELs (124). Meanwhile, single base were prevalent those large...
Abstract Objectives To compare prevalence and severity of diaper dermatitis (DD) in infants toddlers (babies) across three countries (China, USA, Germany), including diapered skin measures caregiver practices. Methods A cross‐sectional study 1791 babies (~600 from each country) was recruited at clinical site. Based on regional toilet‐training habits, exclusively diaper‐wearing were between ages 2‐8 months China 2‐18 the USA Germany. DD measured, as well pH, transepidermal water loss (TEWL),...
The status of vaginal microbiota in persistent high-risk human papilloma virus (HR-HPV) infection is unclear. present work aimed to identify the HPV and explore possible underlying factors.A total 100 women were recruited this study, which 28 presented HR-HPV (P group), 30 showed clearance any subtype (C 42 had no history (NC group). community structure three groups compared based on 16S rRNA sequencing V3-V4 region. diversity differential analysis carried out detect potential factors...
Sarcopenia is an age-related clinical condition and associated with increased risk of adverse outcomes. However, to date, there no global standard for the diagnosis sarcopenia, fewer serum biomarkers have been suggested sarcopenia. It is, thus, important that sarcopenia-related serological diagnostic markers be explored. The present study was based on Asian Working Group 2019 (AWGS 2019) criteria assess whether aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio fasting...
In this work, we prepared an in situ gel-forming composite drug delivery system (DDS) to treat colorectal peritoneal carcinomatosis. The DDS was based on curcumin loaded polymeric micelles (Cur-M) and thermosensitive hydrogel. Cur-M had a particle size of 27.1 ± 1.3 nm with polydisperse index 0.149 0.017, the loading encapsulation efficiency were 14.82 0.07 98.83 0.45%, respectively. hydrogel (Cur-H) free-flowing sol at ambient temperature, converted into non-flowing gel body serving as...
In 2012 the US Preventive Services Task Force released recommendations against prostate specific antigen (PSA) based screening for cancer, but did not fully address via digital rectal exam (DRE). As such, many practitioners continue to perform DRE in attempts identify men with clinically significant cancer (CSPC). This study seeks determine value of detecting CSPC era PSA-based screening.Data from Prostate, Lung, Colorectal, and Ovarian (PLCO) Screening Trial, a nationwide population-based...
Osteosarcoma (OS) is the most common primary bone tumor in children and adolescents. Long noncoding RNAs (lncRNAs) are a class of transcriptional products genome without protein-coding potential. Recently, lncRNA Ewing sarcoma-associated transcript 1 (EWSAT1) was functionally identified sarcoma, highly aggressive pediatric tumor. However, whether EWSAT1 plays role OS remains unclear. In present study, gain- loss-of-function assays demonstrated that enhanced cell proliferation, migration,...
Abstract Recently, solar‐driven interfacial evaporation (SDIE) has been developed quickly for low‐cost and sustainable seawater desalination, but addressing the conflict between a high rate salt rejection during SDIE is still challenging. Here, spatial confinement strategy proposed to prepare gel composite solar evaporator (SCE) by loading one thin hydrogel layer onto skeleton of carbon aerogel. The SCE retains hierarchically porous structure aerogels with an optimized water supply induced...
Sarcopenia is an age-related progressive skeletal muscle disorder involving the loss of mass or strength and physiological function. Efficient precise AI algorithms may play a significant role in diagnosis sarcopenia. In this study, we aimed to develop machine learning model for sarcopenia using clinical characteristics laboratory indicators aging cohorts.We developed models baseline data from West China Health Aging Trend (WCHAT) study. For external validation, used Xiamen (XMAT) cohort. We...
The aim of this retrospective clinical study is to assess outcomes and patient satisfaction between laparoscopic lateral suspension (LLS) with mesh high uterosacral ligament (LHUS) for apical prolapse or without anterior prolapse. Patients who underwent LLS LHUS from 2019 2023 at the Second West China Hospital Sichuan University were enrolled in study. objective evaluated on basis anatomical success rate according Pelvic Organ Prolapse Quantification System (POP-Q). subjective assessed using...
Limbic hypermetabolism is a frequently observed manifestation of anti-LGI1 encephalitis on 18 F-FDG PET/CT imaging. In this case report, we present an atypical finding in patient with and negative MRI results. Apart from the expected bilateral limbic system, there was also uncommon intense uptake noted frontoparietal cortex. Subsequent follow-up scans demonstrated normalized metabolism following treatment. The highlights that neocortical can be characteristic feature active
Abstract Background Circular RNA ciRS-7 has been reported to be involved in the progression of various cancers. However, expression and its role clear cell renal carcinoma (ccRCC) remains unclear. This study aimed investigate effect on ccRCC related signaling pathway. Methods was analyzed using quantitative reverse transcription polymerase chain reaction 87 pairs matched adjacent normal tissues. The proliferation invasion determined counting kit-8 assays, respectively. Potential mechanisms...
Abstract Background: Sarcopenia is an age-related skeletal muscle disorder that involves a loss of mass or strength and physiological function. Skeletal deteriorates in both quantity quality. The endocrine system important regulator metabolism. Therefore, we aimed to explore the relationship between biochemical markers sarcopenia. Methods: We used AWGS 2014 as diagnostic criteria for sarcopenia, considering mass, physical performance. A total 2837 elderly female participants over 50 years...
Data loss often occurs in the collection of clinical data. Directly discarding incomplete sample may lead to low accuracy medical diagnosis. A suitable data imputation method can help researchers make better use valuable data.In this paper, five popular methods including mean imputation, expectation-maximization (EM) K-nearest neighbors (KNN) denoising autoencoders (DAE) and generative adversarial nets (GAIN) are employed on an with 28,274 cases for vaginal prolapse prediction. comprehensive...
Genetic variants within the fatty acid desaturase (FADS) gene cluster (human Chr11) are important regulators of long-chain (LC) polyunsaturated (PUFA) biosynthesis in liver and consequently have been associated with circulating LC-PUFA levels. More recently, epigenetic modifications such as DNA methylation, particularly FADS cluster, shown to affect Our lab previously demonstrated strong associations allele-specific methylation (ASM) between a single nucleotide polymorphism (SNP) rs174537...