A5033033100- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Diagnosis and treatment of tuberculosis
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Infectious Diseases and Mycology
- Pneumonia and Respiratory Infections
- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Obstructive Sleep Apnea Research
- Nutritional Studies and Diet
- High Altitude and Hypoxia
- Advanced Chemical Sensor Technologies
- Cerebral Palsy and Movement Disorders
- Emergency and Acute Care Studies
- Occupational Health and Performance
- Eosinophilic Disorders and Syndromes
- Healthcare Decision-Making and Restraints
- Respiratory viral infections research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Polyomavirus and related diseases
Hospital Del Mar
2016-2025
Municipal Institute for Medical Research
2016-2022
Hospital del Mar Research Institute
2016-2022
Parc de Salut
2016-2022
Instituto de Salud Carlos III
2013-2021
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2013-2021
Universitat Autònoma de Barcelona
2016-2020
Universitat Pompeu Fabra
2013-2016
Barcelona Biomedical Research Park
2013
Introduction The Spanish Society of Pulmonology and Thoracic Surgery created a registry for hospitalised patients with COVID-19 the different types respiratory support used (RECOVID). Objectives. To describe profile COVID-19, comorbidities, treatments setting. In addition, we aimed to identify varying profiles according outcomes complexity needed.
Abstract Purpose This study investigates the potential of inflammatory parameters (IP), symptoms, and patient-related outcome measurements as biomarkers severity their ability to predict tuberculosis (TB) evolution. Methods People with TB were included prospectively in Stage-TB conducted at five clinical sites Barcelona (Spain) between April 2018 December 2021. Data on demographics, epidemiology, features, microbiology, Sanit George Respiratory Questionnaire (SGRQ) Kessler-10 Health-Related...
Natalizumab (Tysabri(®)) is a leukocytes chemotaxis inhibitor that decreases the passage through hematoencephalic barrier and it currently used in relapsing-remitting forms of multiple sclerosis (MS). We present patient with allergic rhinoconjunctivitis diagnosed MS who started treatment natalizumab. She began to show mild asthmatic symptoms until she needed admission hospital due respiratory insufficiency. Blood tests showed peripheral eosinophilia thoracic computed tomography scan...
We hypothesized that inflammatory events and reactive oxygen species (ROS) production may be differentially expressed in respiratory limb muscles, blood of a chronic intermittent hypoxia (CIH) experimental model antioxidants TNF‐alpha blockade influence those events. In blood, diaphragm, gastrocnemius rats non‐invasively exposed to CIH (10% hypoxia, 2 h/day, 14 consecutive days) with/without concomitant treatment with either anti‐TNF‐alpha antibody (infliximab) or N‐acetyl cysteine (NAC),...
Abstract Background For still unclear reasons, chronic airway infection often occurs in patients with Chronic Obstructive Pulmonary Disease (COPD), particularly those more severe airflow limitation. Fatty-acid binding protein 4 (FABP4) is an adipokine involved the innate immune response against produced by alveolar macrophages (Mɸ). We hypothesized that levels of FABP4 may be altered COPD infection. Methods In this prospective and controlled study we: (1) compared (ELISA) induced sputum,...
Background: Diagnosis of nontuberculous mycobacteria (NTM) infections remains a challenge. In this study, we describe the evaluation an immunological NTM-interferon (IFN)-γ release assay (IGRA) that developed using glycopeptidolipids (GPLs) as NTM-specific antigens. Methods: We tested NTM-IGRA in 99 samples from pediatric patients. Seventy-five were patients with lymphadenitis: 25 NTM confirmed, 45 unknown etiology but compatible mycobacterial infection and 5 had lymphadenitis caused by...
<h3>Background</h3> The intravenous administration of antibiotics remains the route choice at patient admission. Although early-oral switch once clinical stability has been achieved, demonstrated to be effective and safe in other settings, its implementation pneumology ward not studied. <h3>Purpose</h3> To assess effectiveness safety an antimicrobial protocol pulmonology ward. <h3>Material methods</h3> Quasi-experimental study performed a 400-bed tertiary hospital. was implemented March 2018...
<b>Introduction:</b> Airway infection worsens outcomes in COPD. Fatty-acid binding protein 4 (FABP4) is an adipokine released by alveolar macrophages and epithelial cells that may play a role immunity against airway infection. The aim of the study was to determine relationship between pulmonary FABP4 levels stable COPD patients. <b>Methods:</b> 52 adult patients with clinically (mean age 65.27.9, mean FEV1 59.015.8 % predicted) 29 controls were prospectively enrolled at 5 university...
<b>Aim:</b> To determine treatment determinants of the respiratory microbiome in COPD patients. <b>Methods:</b> Stable outpatients were enrolled, samples from oropharynx (oropharyngeal swab), bronchial tree (sputum), and lung (bronchoalveolar lavage) collected 16SrRNA gene was amplified analyzed (Ilumina). <b>Results:</b> 59 patients included study, 24 them reporting frequent exacerbations (≥2) previous year. Current smoking function (FEV1%) related to a significantly different composition...