Zhanna V. Khailova

ORCID: 0000-0003-3258-0954
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Research Areas
  • Healthcare Systems and Public Health
  • Global Cancer Incidence and Screening
  • Multiple Myeloma Research and Treatments
  • Chronic Lymphocytic Leukemia Research
  • Lung Cancer Diagnosis and Treatment
  • Medical and Agricultural Research Studies
  • Lung Cancer Research Studies
  • Nutrition, Genetics, and Disease
  • Global Public Health Policies and Epidemiology
  • Cervical Cancer and HPV Research
  • Lung Cancer Treatments and Mutations
  • Breast Cancer Treatment Studies
  • Pancreatic and Hepatic Oncology Research
  • Nutrition and Health in Aging
  • Advanced Breast Cancer Therapies
  • Global Healthcare and Medical Tourism
  • Economic Sanctions and International Relations
  • Thyroid and Parathyroid Surgery
  • Economic and Financial Impacts of Cancer
  • Cancer Genomics and Diagnostics
  • Clinical Nutrition and Gastroenterology
  • Sarcoma Diagnosis and Treatment
  • BRCA gene mutations in cancer
  • HER2/EGFR in Cancer Research
  • Thyroid Cancer Diagnosis and Treatment

Ministry of Health of the Russian Federation
2020-2025

Medical Radiological Research Center
2020-2024

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10.15829/1728-8800-2022-3235 article cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2022-04-20

Создание руководства поддержано Советом по терапевтическим наукам отделения клинической медицины Российской академии наук.

10.15829/1728-8800-2024-3996 article RU cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2024-04-01

Онкологические заболевания остаются одной из ведущих причин заболеваемости и смертности в мире. Программы скрининга рака молочной железы, шейки матки колоректального доказали свою эффективность снижении смертности. Однако их успех часто ограничивается доступностью ресурсов, охватом целевой группы населения способностью системы здравоохранения к лечению пациентов с ранними формами заболеваний. Организованный скрининг, опирающийся на четкие протоколы, стандартизированные интервалы постоянный...

10.37469/0507-3758-2024-70-6-1005-1016 article RU cc-by-nc-nd Voprosy Onkologii 2025-01-22

The improvement of screening programs in the constituent entities Russian Federation, particularly introduction for detection human papillomavirus (HPV), will provide new opportunities early cervical cancer. Objective. To assess clinical sensitivity HPV testing and cytology as methods to develop an organizational model improving their effectiveness based on results obtained. Materials methods. following were used study: analytical, statistical, comparative analysis, sociological, expert...

10.17116/profmed20252804123 article EN Russian Journal of Preventive Medicine 2025-04-28

Aim. To determine the most appropriate strategy for screening and early diagnosis of cervical cancer in Russian Federation terms clinical (diagnostic) cost-effectiveness. Materials methods. assess effectiveness various strategies, a systematic review publications on studies evaluating cytological examination human papillomavirus (HPV) testing its precancerous conditions was conducted. This analysis included results that assessed sensitivity specificity diagnostic tests used programs....

10.17650/1994-4098-2025-21-1-86-105 article EN cc-by Tumors of female reproductive system 2025-05-08

// P.A. Shatalov 1 , N.A. Falaleeva E.A. Bykova D.O. Korostin 2 V.A. Belova A.A. Zabolotneva A.P. Shinkarkina A. Yu Gorbachev 3 M.B. Potievskiy V.S. Surkova Zh V. Khailova Kulemin Denis Baranovskii 4 Kostin A.D. Kaprin and P.V. Shegai National Medical Research Radiological Centre of the Ministry Health Russian Federation, Obninsk 249036, Russia Center for Precision Genome Editing Genetic Technologies Biomedicine, Pirogov University, Moscow 117997, FSBI "Lopukhin Federal Clinical...

10.18632/oncotarget.28512 article EN Oncotarget 2024-02-05

Lung cancer has the highest morbidity rate among all malignant tumors in men and mortality women Russia. In total, 49 145 new cases of lung were registered (diagnosed) Russia 2019. The majority are related to exogenic carcinogens mainly tobacco smoke. For several decades surgical resection with preoperative cytotoxic therapy was an optimal approach for maximal cure rate. This year recommendations updated strategies including adjuvant anti-PD-L1 atezolizumab following completion chemotherapy...

10.26442/18151434.2021.3.201048 article EN Journal of Modern Oncology 2021-11-19

Malignant tumors are the problem of high social importance. High incidence, late diagnostic and lethality malignant factors that determine significance oncological alertness aimed at disease detection early treatment.

10.35576/article_5d651dbc693279.10409311 article EN Vestnik Roszdravnadzora 2019-08-22

Background. Burden of disease estimation allows analyses to be carried out integrally, including cause and effect assessment. the rate life years lost due premature mortality is part burden analysis. given that cancer steadily increasing, analysis number makes it possible identify new strategic directions, as well adjust decisions already made, in health care patients. Purpose : estimate loss expectancy a result from population Russian Federation. Material Methods . was using international...

10.21294/1814-4861-2023-22-5-14-27 article EN cc-by Siberian Journal of Oncology 2023-11-14

The Guidelines contain information on the theoretical foundations of screening for malignant neoplasms breast, regulatory legal acts regulating organization activities within framework medical examination certain groups adult population, diagnostic algorithms and routing examined persons. have been developed heads organizations providing primary health care in terms organizing processes, internists, general practitioners, workers from among secondary personnel who are directly involved...

10.15829/3034-4123-2024-5 article EN 2024-10-22

Prostate cancer (RPP) is a malignant neoplasm that arises from the epithelium of prostate gland (PJ). рак предстательной железы; клинические рекомендацииThethiology and pathogenesis this disease remain poorly studied. Many studies are aimed at studying diet, food, hormonal impact, as well infections in etiology RLPG. The prevalence RPL depends on ethnic geographical features. highest incidence African Americans living United States (60% higher than white Americans), least high - Chinese...

10.26442/18151434.2021.2.200959 article EN Journal of Modern Oncology 2021-08-16

Gastric cancer remains one of the most common malignancies in Russia. Despite steady decrease gastric incidence it still reaches 24.65 per 100 000 population (crude rate) 2019 with about 36 new cases annually. More than 29 people die every year. High mortality rate is mostly caused by an extremely significant proportion patients metastatic disease which reached 40.1% 2019. The majority related to Helicobacter pylori infection, salty diet, tobacco exposure as well hereditary syndromes....

10.26442/18151434.2021.4.201239 article EN Journal of Modern Oncology 2021-12-15

Breast cancer (BC) is a malignant tumor originating from the epithelium of breast tissue. There no single etiological factor in development cancer. In 310% patients with cancer, disease associated presence mutations gene (BRCA) 1, BRCA2, CHEK, NBS1, TP53. other patients, sporadic.

10.26442/18151434.2021.1.200823 article EN Journal of Modern Oncology 2021-05-19

The analysis of current data concerning the use oral nutrition supplements (ONS) in cancer patients has been performed. aim research is improving effectiveness medical by clarifying terms, definitions, developing an applied classification ONS formulas and outlining basic approaches for their use. Material methods Using keywords «cancer», «oral nutritional supplements», «siping», literature was searched such databases as eLIBRARY (elibrary.ru) MEDLINE (ncbi.nlm.nih.gov) Russian English....

10.24411/0042-8833-2020-10008 article EN Problems of Nutrition 2020-01-24

Today, the cancer registry is an information and analytical system for collecting, storing analyzing about malignant neoplasms throughout Russian Federation, as well state of specialized oncological care. The value that its can should be analyzed: allows a statistical assessment disease, to see differences in morbidity, including depending on region. Purpose study analyze mortality prevalence Federation period 2012–2022. Materials methods. Calculation analysis indicators were carried out...

10.21045/1811-0185-2024-11-39-51 article EN Manager Zdravookhranenia 2024-12-02

The analysis of the current evidence base concerning use oral nutritional supplements (ONS) in gastric cancer (GC) has been made. Databases scientific information eLIBRARY.ru and PubMed were used. Emphasis is placed on randomized clinical trials meta‑analyses. application ONS suggested for all patients who undergo to surgical treatment GC. Its allows increasing protein energy consumption, improving quality life, some parameters status immunity (albumin, blood lymphocytes etc.). In with...

10.17709/2409-2231-2021-8-1-5 article EN cc-by Research and Practical Medicine Journal 2021-03-10

Introduction: despite quite low morbidity with up to 6 thousand cases per year in Russia, therapy for unresectable liver tumors is based on costly tyrosine kinase inhibitors or anti-PD‑1L agents thus leading extremely high costs life saved. In the meantime, transaterial radioembolization (TARE)technique reported show better outcomes this patient group compared conservative treatment and transarterial chemotherapy (TACT). This article researches strategic options regionwide programs focused...

10.21045/1811-0185-2022-4-10-18 article EN Manager Zdravoochranenia 2022-04-01
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