- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Bacterial Identification and Susceptibility Testing
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- Neutropenia and Cancer Infections
- Antibiotic Use and Resistance
- Central Venous Catheters and Hemodialysis
- Hematological disorders and diagnostics
- Bacterial Infections and Vaccines
- Antimicrobial Resistance in Staphylococcus
- Neonatal and Maternal Infections
- Sepsis Diagnosis and Treatment
- Public Health and Environmental Issues
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 and Mental Health
- Cardiac, Anesthesia and Surgical Outcomes
- Kawasaki Disease and Coronary Complications
- Influenza Virus Research Studies
- Antibiotic Resistance in Bacteria
- COVID-19 Impact on Reproduction
- SARS-CoV-2 and COVID-19 Research
- Virology and Viral Diseases
- Meta-analysis and systematic reviews
Centro Medico Nacional Siglo XXI
2015-2025
Mexican Social Security Institute
2016-2025
Universidad Nacional Autónoma de México
2019-2024
Institute of Medical Sciences
2012
Clínica Santa María
2012
Instituto Nacional de Pediatria
2008
Office of Infectious Diseases
2005
MRC Epidemiology Unit
2001
Pemex (Mexico)
1999
The study population is defined as a set of cases, determined, limited, and accessible, that will constitute the subjects for selection sample, must fulfill several characteristics distinct criteria. objectives this manuscript are focused on specifying each one elements required to make participants research project, during elaboration protocol, including concepts population, criteria sampling methods. After delineating researcher specify participant has comply. include specific denominated...
Objectives: We report the results of International Nosocomial Infection Control Consortium prospective surveillance study from January 2004 to December 2009 in 33 pediatric intensive care units 16 countries and impact being a private vs. public hospital income country level on device-associated health care-associated infection rates. Additionally, we aim compare these findings with Centers for Disease Prevention National Healthcare Safety Network annual show differences between developed...
El análisis estadístico se divide en 2 grandes componentes: el descriptivo y inferencial. Una inferencia es la elaboración de conclusiones a partir las pruebas que realizan con los datos obtenidos una muestra. Las estadísticas emplean finalidad establecer probabilidad conclusión obtiene muestra sea aplicable población cual obtuvo. Sin embargo, elección prueba estadística apropiada, general, representa un reto para investigadores principiantes. Para elegir necesario tomar cuenta 3 aspectos:...
Descriptive statistics is the branch of that gives recommendations on how to summarize clearly and simply research data in tables, figures, charts, or graphs. Before performing a descriptive analysis it paramount its goal goals, identify measurement scales different variables recorded study. Tables charts aim provide timely information results an investigation. The graphs show trends can be histograms, pie "box whiskers" plots, line graphs, scatter plots. Images serve as examples reinforce...
Some studies suggested that adequate levels of vitamin D (VD) decrease the risk severe COVID-19. Information about effectiveness VD supplementation in children is scarce. To assess efficacy and safety compared to standard care hospitalized with An open-label randomized controlled single-blind clinical trial was carried out. We included patients from 1 month 17 years, moderate COVID-19, who required hospitalization supplemental oxygen. They were into two groups: group, which received doses...
ABSTRACT Between 1997 and 2000 a single multidrug-susceptible methicillin-resistant Staphylococcus aureus clone, M (sequence type 30 [ST30]-staphylococcal cassette chromosome mec [SCC ] IV), was present in pediatric hospital Mexico City, Mexico. In 2001 the international multidrug-resistant New York-Japan clone (ST5-SCC II) introduced into hospital, completely replacing by 2002.
Biofilm production has been established as a virulence factor which allows Staphylococcus to adhere and persist in medical devices. The objective was determine whether therapeutic failure patients infected with spp. is linked biofilm production, the presence of ica operon, bacterial insertion sequence element IS256.Staphylococcus isolates from device-related infections were collected. Therapeutic proper antimicrobial treatment registered. phenotype determined by Congo red test agar...
Las revisiones sistemáticas son investigaciones secundarias que compilan los resultados publicados obtenidos a partir de estudios en seres humanos. El término metaanálisis es utilizado para describir el análisis estadístico la combinación dos o más originales, cuales debieron ser seleccionados una revisión sistemática. De esta forma, no puede haber sin surgen debido al incremento exponencial información, facilitar un estudio analice críticamente y discrimine puedan útiles práctica clínica....
Los estudios experimentales se utilizan para evaluar la eficacia y efectividad de una intervención terapéutica (farmacológica o quirúrgica), preventiva (como vacunación los cambios estilo vida) educativa (por ejemplo, taller mejorar calidad atención a salud). Existen diferentes experimentales, pero en actualidad reconoce que el ensayo clínico controlado aleatorizado es brinda mayor grado evidencia. Cuando no puede llevar cabo este tipo investigación tienen disponibles cuasiexperimentales,...
Research on human subjects cannot occur if it does not comply with these ethical principles: autonomy, beneficence and justice. The historical antecedents that emphasized the need to have documents guide researchers' behavior point regrettable events for humanity. Even though first recommendations were published more than 50 years ago in Declaration of Helsinki, is possible find examples investigations been conducted without complying aforementioned principles. Approval by an ethics...
combinations of drugs has been proposed as an alternative for oxacillin-resistant staphylococci infections, however, limited information about in vitro are available multi-resistant strains. The objective this study was to describe the interaction beta-lactams combination with vancomycin or amikacin against 26 oxacillin and amikacin-resistant nosocomial Staphylococcus spp. isolates. activity dicloxacillin plus amikacin, cephalothin vancomycin, imipenem evaluated by checkerboard synergy tests...
The concept of validity in research refers to what is true or close the truth. It considered that results an investigation will be valid when study free errors. errors biases appear development research, are due methodological problems and, general, can grouped into three: selection bias, measurement bias and confusion bias. In this article, addressed; type error has three axes: 1) subject, 2) instrument for variable (s), 3) those who make evaluation (s). To improve obtaining data prevent...
Objective. To establish the current situation of antimicrobial resistance and antibiotic consumption in Mexican hospitals. Materials methods. Antimicrobial susceptibility data from blood urine isolates were collected. Defined daily dose (DDD) consumption/100 occupied beds (OBD) was calculated. Results. Study period: 2016 2017. Of 4 382 isolates, E. coli K. pneumoniae most frequently reported, with >30% for drugs tested, only carbapenems amikacin <20%. A. baumannii had resistance...
Congenital heart diseases are among the most common congenital malformations. Approximately 50% of patients with disease undergo cardiac surgery. Nosocomial infections (NIs) main complications and an important cause increased morbidity mortality associated diseases. This study's objective was to identify risk factors development NIs after surgery in newborns disease.This a nested case-control study that included 112 newborns, including 56 cases (with NI) controls (without NI). Variables...