A5100351946- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Forensic and Genetic Research
- Molecular Biology Techniques and Applications
- RNA modifications and cancer
- Cytokine Signaling Pathways and Interactions
- Immune Response and Inflammation
- Renal and related cancers
- Diet and metabolism studies
- IL-33, ST2, and ILC Pathways
- Liver physiology and pathology
- MicroRNA in disease regulation
- Flame retardant materials and properties
- Birth, Development, and Health
- Immune Cell Function and Interaction
- Genetic diversity and population structure
- Advanced materials and composites
- Asthma and respiratory diseases
- Gut microbiota and health
- Dam Engineering and Safety
- DNA Repair Mechanisms
- Cancer-related molecular mechanisms research
- Epigenetics and DNA Methylation
- Psoriasis: Treatment and Pathogenesis
- Organ Transplantation Techniques and Outcomes
Sichuan University
2016-2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024-2025
Chongqing Medical University
2024-2025
First Affiliated Hospital of Zhengzhou University
2025
West China Second University Hospital of Sichuan University
2010-2024
Anhui Medical University
2024
State Key Laboratory of Biotherapy
2022-2024
Zhengzhou University
2024
Soochow University
2024
First Affiliated Hospital of Soochow University
2024
Harsh-condition protective materials are essential for resisting various types of environmental damage, such as fire, microbes, scratches, and etc. However, integrating multiple functions in one transparent flexible material without sacrificing each other remains a formidable challenge. Here, we demonstrate smart-puffing phosphite-protonated siloxane (PSiP) that simultaneously exhibits excellent fire protection, high-temperature insulation, antibacterial, antimold, self-healing properties. A...
The inherent flammability of most polymeric materials poses a significant fire hazard, leading to substantial property damage and loss life. A universal flame-retardant protective coating is considered as promising strategy mitigate such risks; however, simultaneously achieving high transparency the coatings remains great challenge. Here, inspired by moth eye effect, we designed nanoporous structure into that leverages hydrophilic-hydrophobic interactive assembly facilitated phosphoric acid...
Conventional instrumentation has difficulty to measure displacements inside laboratory-scale physical models. In this paper, an innovative fiber Bragg grating (FBG) sensing bar been developed perform high-accuracy and real-time monitoring of internal displacements. According Euler-Bernoulli beam theory, the strain distribution measured by quasi-distributed FBG sensors adhered on surface can be used compute displacement profile along bar. The effectiveness verified calibration tests. model...
Abstract Interleukin‐17 (IL‐17) has been shown to play an important role in the pathogenesis of inflammation and autoimmune disorders, be elevated several types cancer. The present study analyzed polymorphisms IL‐17 gene their impact on bladder TaqMan® SNP Genotyping Assay was used genotype rs2275913 IL‐17A rs763780 IL‐17F 301 cancer patients 446 ethnicity‐matched healthy controls. frequencies AA A allele rs2275913, as well TT T were significantly higher than that controls, indicating both...
Abstract Purpose: CXC chemokine ligand 10 (CXCL10) is a potent inhibitor of angiogenesis. We wonder whether the combination CXCL10 with cisplatin would improve therapeutic antitumor efficacy. Experiment Design: evaluated activity therapy in immunocompetent C57BL/6 and BALB/c mice bearing LL/2 Lewis lung cancer CT26 colon adenocarcinoma, respectively. Mice were treated either s.c. at 25 μg per kg day once daily for 30 days, cycled twice (5 mg/kg i.p. on days 14 21 after initiation CXCL10), or...
Abstract Background The association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and serum lipid profiles is still controversial in diverse ethnics. Bai Ku Yao an isolated subgroup the minority China. aim present study was to eveluate MTHFR C677T several environmental factors with levels Guangxi Han populations. Methods A total 780 subjects 686 participants Chinese were randomly selected from our previous stratified randomized cluster samples. Genotyping performed by...
Traumatic brain injury (TBI) causes high rates of worldwide death and morbidity because the complex secondary cascade. Circular ribonucleic acid (RNA) (circRNA), a type RNA that forms covalently closed continuous loop, may be involved in regulation it is expressed widely contributes to large class post-transcriptional regulators. Deep sequencing (RNA-seq) bioinformatic analysis were performed investigate expression profile function circRNAs mouse cortex after controlled cortical impact...
Transplantation of neural stem cells (NSCs) improves functional outcomes following traumatic brain injury (TBI). Previously we demonstrated that human NSCs (hNSCs) via releasing glial cell line-derived neurotrophic factor (GDNF), preserved cognitive function in rats parasagittal fluid percussion. However, the underlying mechanisms remain elusive. In this study, report NSC grafts significantly reduce TBI-induced axonal fimbria and other regions by blocking abnormal accumulation amyloid...
Early diagnosis and treatment of preeclampsia are essential for prevention seizure development fetus maturation. Although various methods have been developed predicting or monitoring the onset preeclampsia, a simple assay that can be used as home point care test remains unavailable. We attempted to find urinary protein could biomarker developing such test. Urinary samples were collected from 124 135 healthy pregnant women screening using array technology quantification by ELISA. A protein,...
Sorafenib is a small-molecule multi-kinase inhibitor approved by FDA as an oral agent for the treatment of hepatocellular carcinoma (HCC) and renal cell carcinoma. However, unresponsiveness acquired resistance are commonly observed, which hinder clinical use sorafenib. As combination therapy promising approach to improve its efficacy, we investigated if sorafenib luteolin effective in killing human HCC cells. Cell death was examined lactate dehydrogenase (LDH) releasing assay. Apoptosis...
Background Numerous researches have investigated the correlation between single nucleotide polymorphisms (SNPs) in transcription factor forkhead box protein 3 (Foxp3) gene and development of various cancers. However, relationship Foxp3 polymorphism bladder cancer (BC) remain unclear. Method This hospital-based case-control study enrolled a total 316 patients diagnosed with BC 643 healthy controls. Two SNPs (rs3761548 C/A, rs5902434 del/ATT) were selected, genotyping samples was performed...
Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between microbiota, host in T2DM development remains unclear. Rhesus macaques may best animal model investigate these relationships given their spontaneous of T2DM. We identified eight conducted a comprehensive study investigating using multi-omics sequencing technology. Our results from 16S rRNA, metagenome, metabolome transcriptome analyses that...
Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between microbiota, host in T2DM development remains unclear. Rhesus macaques may best animal model investigate these relationships given their spontaneous of T2DM. We identified eight conducted a comprehensive study investigating using multi-omics sequencing technology. Our results from 16S rRNA, metagenome, metabolome transcriptome analyses that...
This study aimed to translate the Edmonton-33 scale (E-33) into Chinese and evaluate its reliability validity in patients with head neck cancer (HNC). In Phase 1, E-33 was translated from English using Brislin double-back translation method. Content evaluated by a panel of experts, pilot test conducted small sample HNC patients. 2, cohort 510 Henan Hubei provinces recruited. Psychometric properties were assessed through item analysis; testing (including Cronbach's alpha, test-retest...
This study aimed to evaluate the safety and efficacy of endovascular treatment for post-thrombotic syndrome (PTS) in lower extremities, identify risk factors contributing in-stent restenosis. Patients with PTS who received at our institution from May 2016 April 2022 were included this study. Clinical symptoms systematically assessed utilizing Villalta score, CEAP (Clinical, Etiological, Anatomical, Pathophysiological) classification, Venous Severity Score (VCSS). Primary secondary patency...
Although good progress has been achieved in expanding immunization of children China, disparities exist across different provinces. Information gaps both from the service supply and demand sides hinder timely vaccination rural areas. The rapid development mobile health technology (mHealth) provides unprecedented opportunities for improving services reaching underserved populations. However, there is a lack literature that rigorously evaluates impact mHealth interventions on coverage as well...