A5084424878- Immunodeficiency and Autoimmune Disorders
- Hematopoietic Stem Cell Transplantation
- Hemoglobinopathies and Related Disorders
- Transplantation: Methods and Outcomes
- Virus-based gene therapy research
- Lung Cancer Treatments and Mutations
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Renal Diseases and Glomerulopathies
- HIV/AIDS drug development and treatment
- Blood groups and transfusion
- Multiple Myeloma Research and Treatments
- Vascular Malformations and Hemangiomas
- Peptidase Inhibition and Analysis
- Lymphoma Diagnosis and Treatment
- Polyomavirus and related diseases
- Cancer Treatment and Pharmacology
- Cytomegalovirus and herpesvirus research
- Reproductive tract infections research
- Case Reports on Hematomas
- Bartonella species infections research
- Bone and Joint Diseases
- Breast Lesions and Carcinomas
- Kruppel-like factors research
- Neurofibromatosis and Schwannoma Cases
- Congenital Diaphragmatic Hernia Studies
University Hospitals Seidman Cancer Center
2024
Cleveland Clinic
2021-2024
Maulana Azad Medical College
2019-2021
Case Western Reserve University
2019-2021
University School
2021
MetroHealth
2018-2020
MetroHealth Medical Center
2018-2020
John H. Stroger, Jr. Hospital of Cook County
2015-2018
University College of Medical Sciences
1993
Guru Teg Bahadur Hospital
1993
Opinion statement Desmoid tumors are rare with a tendency to infiltrate locally. The lack of standard treatment approach makes choosing the most appropriate for patients challenging. Most experts recommend watchful observation asymptomatic as spontaneous regression tumor is observed in up 20% patients. Upfront resection desmoid has fallen out favor due high morbidity and relapse rates associated tumor. Systemic therapy evolved over several decades. Where chemotherapy, hormonal therapy,...
OBJECTIVE:To study whether there is an association between nutritional intake during the first week of life and severity bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants. METHODS:In a retrospective cohort study, medical records all ELBW infants admitted to our Neo natal Intensive Care Unit (2010–2017) were reviewed for infants' demographics, clinical characteristics, their life, BPD risk factors. RESULTS:During period 226 identified whom 67% (151/226) had...
Insulin-derived amyloidosis is a rare form of composed insulin fibrils. The pH and concentration are known to influence the conformational state hormone, with an increasing favouring more complex conformation. Concentrated delivers large amount localized area, raising possibility inducing changes, forming fibrils leading amyloidosis.A middle-aged woman long history Type 2 diabetes mellitus, treated concentrated human (U-500 insulin) presented nodular lesions at site her daily injections. A...
Metastasis to the breast from an extra-mammary malignancy has been documented in literature, however cervical cancer metastasis is very rare. Thirty-eight cases of metastatic deposit have reported literature. Though most patients present with a lump, it difficult clinically distinguish primary deposit. Histopathology tissue, aided immune-histochemical staining pattern provides definitive diagnosis. Our patient, 51-year old woman presented lump and history post-menopausal bleeding. Upon...
Key Clinical Message Primary malignant myelomatous pleural effusion (PMMPE) occurs in less than 1% of patients with multiple myeloma and is diagnosed either by visualization plasma cells on cytology or positive flow cytometry. The presence immature characterized high nucleus to cytoplasm ratio, visible nucleolus Mott Russell bodies are independent poor prognostic factors. clinician should differentiate PMMPE from secondary as it associated a significantly worse prognosis overall survival.
Erlotinib is one of the most widely used tyrosine kinase inhibitor targeting human epidermal growth factor receptor. Since its introduction, it has revolutionized treatment advanced non-small cell lung cancer. Skin rashes and diarrhea are often reported side effects erlotinib however also associated with interstitial pneumonitis or disease, which turns out to be fatal complication using this medicine. Though scarcely in western world, association disease receptor attracted a lot attention...
Wiskott Aldrich syndrome (WAS) is a rare disease and hematopoietic stem cell transplant (HCT) considered the treatment modality of choice for WAS. We conducted cross-sectional analysis on KIDS' pediatric inpatient database compared hospitalization rates, complications healthcare utilizations in non-transplant arms. Of 383 admissions with diagnosis WAS between 2006-2012, 114 underwent 269 did not. The arm included older children, female patients more African Americans. Death income payer...
Elderberry flower extract is marketed as an herbal supplement with purported benefits in boosting the immune system. The use of elderberry increased during coronavirus pandemic. However, interaction cytotoxic medicines has remained elusive. Pazopanib a multikinase inhibitor approved for patients diagnosed soft‑tissue sarcoma. present study reported on case middle‑aged woman localized intermediate‑grade sarcoma left sartorius muscle who received neoadjuvant pazopanib radiation therapy....
Key Clinical Message Chronic iron deficiency can be associated with nail deformities like Koilonychia and Platynychia. It also esophageal webs (Plummer‐Vinson syndrome or Patterson‐Brown‐Kelly syndrome) causing dysphagia in the patient. Though pathogenesis of this association remains anecdotal presence these physical findings should prompt clinician towards considering chronic as cause anemia.
4069 Background: Squamous cell carcinoma of the gallbladder (SCCGB) is a rare subtype cancer (GBC) with its distinct biological behavior, different from gall bladder adenocarcinoma (ACGB). We aimed to study demographics and survival patients SCCGB by reviewing SEER database. Methods: From 1973-2012, we identified 17328 primary GBC data extracted 384 cases examine patient characteristics clinical outcomes histology stage. Associated factors were estimated multivariable logistic regression...
TPS239 Background: Cures are rare in advanced UC. The EGF pathway is involved proliferation, survival, angiogenesis, and metastasis of cancers including EGFR overexpressed 50% Its expression correlates with higher tumor grade, stage, disease progression, an independent adverse prognostic factor for overall survival (OS) disease-specific survival. majority UC metastases over-express EGFR. Resistance to chemotherapy bladder cancer lines involves up-regulation can be overcome by inhibition....
Abstract Gonorrhea is the most common sexually transmitted disease globally, affecting both men and women equally. It has a myriad of presentations which can vary from local to disseminated gonococcal infection. We are reporting first case arthritis leading acute osteomyelitis femoral head in young adult with Charcot-Marie-Tooth that occurred over period 2 weeks. affect joints cause arthritis, there have been reports untreated after months. Here we report spread bones causing adult. A high...
Fc γ receptor IIB (FcγRIIB) is an inhibitory molecule capable of reducing antibody immunotherapy efficacy. We hypothesized its expression could confer resistance in patients with diffuse large B-cell lymphoma (DLBCL) treated anti-CD20 monoclonal (mAb) chemoimmunotherapy, outcomes varying depending on mAb (rituximab [R]/obinutuzumab [G]) because different mechanisms action. evaluated correlates between FCGR2B messenger RNA and/or FcγRIIB protein and 3 de novo DLBCL discovery cohorts R plus...