A5030975246- Reproductive Physiology in Livestock
- Veterinary Equine Medical Research
- Veterinary Medicine and Surgery
- Microbial infections and disease research
- Animal health and immunology
- Platelet Disorders and Treatments
- Vector-borne infectious diseases
- Blood groups and transfusion
- Veterinary Pharmacology and Anesthesia
- T-cell and Retrovirus Studies
- Parasitic Infections and Diagnostics
- Ruminant Nutrition and Digestive Physiology
- Effects of Environmental Stressors on Livestock
- Helminth infection and control
- Hematological disorders and diagnostics
- Dialysis and Renal Disease Management
- Muscle metabolism and nutrition
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Vector-Borne Animal Diseases
- Parasite Biology and Host Interactions
- Venomous Animal Envenomation and Studies
- Inflammatory mediators and NSAID effects
- Blood Coagulation and Thrombosis Mechanisms
- Rabies epidemiology and control
- Venous Thromboembolism Diagnosis and Management
Universidade Estadual Paulista (Unesp)
2016-2025
Universidad de la República de Uruguay
2022
Fundação de Estudo e Pesquisa em Medicina Veterinária e Zootecnia
2012-2020
Fundação de Apoio à Universidade Federal de São Paulo
2016
Universidade Vila Velha
2010
Faculdade Brasil
2009
Associação Brasileira de Oncologia Veterinária
2009
University of Veterinary Medicine
2007
Obstetric Anaesthetists' Association
2007
Universidade de São Paulo
2005
The skin is a critical organ for the maintenance of integrity and protection organism. When wound occurs, sequence healing mechanisms triggered to reconstruct wounded area. β-caryophyllene sesquiterpene in Copaifera langsdorffii oleoresin with antioxidant anti-inflammatory potential. On basis previous studies C. langsdorffii, was selected evaluate its potential pharmacological mechanisms. excision model used male Wistar rats macroscopic, histological, immunohistochemical biochemical analyses...
Abstract Objective —To evaluate adverse effects of long-term oral administration carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs. Animals —36 adult Procedures —Values for CBC, urinalysis, serum biochemical urinalyses, occult blood feces were investigated before 7, 30, 60, 90 days after daily (n = 6 dogs/group) lactose (1 mg/kg, control treatment), etodolac (15 mg/kg), (0.1 carprofen (4 ketoprofen (2 mg/kg 4 days, followed by 1 thereafter) or 3 with 4-day...
The current treatments for anxiety disorders and depression have multiple adverse effects in addition to a delayed onset of action, which has prompted efforts find new substances with potential activity these disorders. Citrus aurantium was chosen based on ethnopharmacological data because traditional medicine refers the genus as useful diminishing symptoms or insomnia, C. more recently been proposed an adjuvant antidepressants. In present work, we investigated biological underlying...
Cymbopogon citratus (lemongrass) is currently used in traditional folk medicine. Although this species presents widespread use, there are no scientific data on its efficacy or safety after repeated treatments. Therefore, work investigated the toxicity and genotoxicity of lemongrass's essential oil (EO) male Swiss mice. The single LD50 based a 24 h acute oral study was found to be around 3500 mg/kg. In repeated-dose 21-day study, mice were randomly assigned two control groups, saline- Tween...
Skin wound healing is a highly complex event that involves different mediators at the cellular and molecular level. Lupeol has been reported to possess biological activities, such as anti-inflammatory, antioxidant, antidiabetic, in vitro properties, which motivated us proceed with vivo studies. We aimed investigate effect of lupeol-based cream for 3, 7, 14 days. Wound excisions were induced on thoraco-lumbar region rats topically treated immediately after injury induction. Macroscopic,...
Based on ethnopharmacological indications that Mentha species may be used in the treatment of gastrointestinal diseases, this study aimed to characterize gastroprotective mechanisms menthol (ME), major compound essential oil from genus Mentha. The action ME was analyzed gastric ulcers were induced by ethanol or indomethacin Wistar male rats. responsible for effect assessed analyzing amount mucus secreted, involvement non-protein sulfhydryl (NP-SH) compounds, calcium ion channels and...
Alchornea glandulosa (Euphorbiaceae) is a plant used in folk medicine as an antiulcer agent. Rats pretreated with methanolic extract obtained from the leaves of A. (AG) showed dose-dependent effect and significant reduction gastric ulcers induced by absolute ethanol at doses 500 (57%) 1000 mg/kg (85%) relation to control group. Pretreatment mice AG (500, mg/kg, p.o.) activity significantly decreased severity lesions caused HCl/ethanol non steroidal anti inflammatory drug-induced lesions....
Therapeutic plasma exchange (TPE) has been used in immunological diseases, conditions of hyperviscosity, and the removal protein-bound drugs toxins. Although complications may be encountered, its use reported to offer some degree safety clinical improvement for dogs. This case report aimed describe feasibility TPE Five dogs with immune-mediated hemolytic anemia (IMHA) and/or canine visceral leishmaniasis (CVL) not responsive immunosuppressive treatment underwent by centrifugation. Physical,...
Hematophagous gastrointestinal parasites cause significant economic losses in small ruminant grazing systems. The growing reports of multi-drug resistant call for intensive research on alternative treatments anthelmintics to help ruminants cope with these parasites. Two-month-old lambs mean body weight (BW) 22.5 kg were experimentally infected a multidrug-resistant Haemonchus contortus strain. Infected animals dosed orally Cymbopogon schoenanthus essential oil evaluate its anthelmintic...
Thrombosis has been associated to some diseases like hyperadrenocorticism (HAC). Several drugs can alter the balance, such as corticosteroid prednisone, used mainly for its anti-inflammatory and immunosuppressive effects. It is known that hypercortisolism stimulate thrombi formation by increasing coagulation factors decreasing fibrinolysis. However it not how prednisone administration affects hemostasis in dogs if dose dependent. The aim of this study, therefore, was demonstrate effects on...
Dioctophyma renale is a large nematode distributed worldwide that may cause progressive and severe destruction of renal parenchyma.The present study aimed to evaluate pre- post-operatively dogs submitted right nephrectomy due D. assess the histopathological damage removed kidney.Eight crossbred dogs, aged from 12 48 months were unilaterally nephrectomized presence evaluated. Physical examination, urinalysis, complete blood count, serum biochemistry, abdominal ultrasound performed immediately...
OBJECTIVE--To compare ultrasonographic, CT, and surgical findings in dogs infested with giant kidney worms (Dioctophyme renale). DESIGN--Case series. ANIMALS--15 crossbred infected D renale. PROCEDURES--Immediately after ultrasonography was performed dorsal recumbency, sequential transverse images of the abdomen were acquired a helical CT scanner. After plain contrast nonionic iodinated agent. Subsequently, exploratory celiotomy performed. RESULTS--In corticomedullary area right 12 dogs,...
This prospective, comparative, randomized, horizontal, and double-blind clinical study investigated the efficacy of leucocyte-poor platelet-rich plasma (PRP, n=8) or allogeneic adipose-derived stem cells (ADSC, in dogs with bilateral degenerative hip joint disease (DHJD). Sixteen were treated two intra-articular injections PRP ADSCs, within a 30-day interval. The Canine Brief Pain Inventory (CBPI), Helsinki Chronic Index (HCPI), Visual Analogue Scales for pain (VAS-pain) locomotion (VAS-loc)...
Several species of Bauhinia are used in traditional medicine for the treatment gastrointestinal diseases, diabetes, and inflammation, among other conditions. The aim this study was to investigate antiulcer effect a hydroalcoholic extract from leaves B. holophylla . chemical profile determined by HPLC-PAD-ESI-IT-MS. A dose-effect relation constructed using ethanol-induced gastric ulcer model male Wistar rats. Histological analyses studies antioxidant anti-inflammatory activities were...
This study was carried out to evaluate the effects of supplementation with different levels copper (Cu) and zinc (Zn), using two mineral sources (sulphate hydroxy forms), on bone characteristics, skin strength/elasticity, haematological parameters broilers. A total 1792 1-day-old male Cobb-500 broiler chickens were randomly distributed among eight dietary treatments, Cu sulphate (CSM) or hydroxychloride (CHC), Zn (ZSM) (ZHC). The treatments as follows: (1) low-CSM/high-ZSM, (2)...
As ectothermic animals, snakes depend exclusively on the environment for proper temperature maintenance, which may greatly influence their activity. Twenty-five adult Boa constrictor amarali maintained in captivity were used to determine of seasons hematologic values and electrophoretic profile hemoglobin. A complete blood cell count (CBC) examination hemoparasites performed summer winter 2004. Hemoglobin was stored later electrophoresis. Significant differences (P < 0.05) obtained RBC, WBC,...
Similarly to other reptiles, snakes are ectothermic animals and depend exclusively on the environment for maintenance of their physiological, biochemical immunological processes. Thus, changes in values can be expected due seasonal influence. Twenty-two adult specimens Boa constrictor amarali kept captivity were used. Blood collections done two different seasons: winter (July 2004) summer (January 2005) following assays: uric acid, aspartate aminotransferase (AST), glucose, cholesterol,...