A5060075380- Ethnobotanical and Medicinal Plants Studies
- Botanical Research and Chemistry
- Phytochemicals and Medicinal Plants
- Heat shock proteins research
- Protein Structure and Dynamics
- Enzyme Structure and Function
- Agricultural Economics and Practices
- Botany, Ecology, and Taxonomy Studies
- Plant responses to water stress
- Microbial Applications in Construction Materials
- Glutathione Transferases and Polymorphisms
- Rice Cultivation and Yield Improvement
- Genomics, phytochemicals, and oxidative stress
- Plant Taxonomy and Phylogenetics
- Microbial Metabolic Engineering and Bioproduction
- Connective Tissue Growth Factor Research
- Cholinesterase and Neurodegenerative Diseases
- Food Science and Nutritional Studies
- Potato Plant Research
- Protein Degradation and Inhibitors
- Pharmacological Effects of Medicinal Plants
- Bacterial biofilms and quorum sensing
- Neuroendocrine regulation and behavior
- Wildlife Ecology and Conservation
- Diet, Metabolism, and Disease
Tulane University
2022-2025
University of Arkansas at Fayetteville
2020-2024
Vikrama Simhapuri University
2020
Sri Venkateswara University
2017-2020
Indian Institute of Technology Tirupati
2020
Creative Commons
2017
Osmania University
2010
The present study predicts a three-dimensional model for the histamine H1 receptor and design of antihistamine inhibitors using cloperastine as core molecule by docking studies. In this work, we predicted structure MODELLER9V7 software. protein was developed based on crystal receptor, lysozyme chimera Escherichia virus T4 (PDB ID: 3RZE_A) target collected from PDB data bank. Using molecular dynamics simulation methods, final is obtained further analyzed VERIFY3D PROCHECK programs, confirming...
Abstract Liver fibrosis is the common outcome of many chronic liver diseases, resulting from altered cell-cell and cell-matrix interactions that promote hepatic stellate cell (HSC) activation excessive matrix production. This study aimed to investigate functions cellular communication network factor 2 (CCN2)/Connective tissue growth (CTGF), an extracellular signaling modulator CYR61/CTGF/Nov (CCN) family, in fibrosis. Tamoxifen-inducible conditional knockouts mice hepatocyte-specific...
Concrete is a strong and fairly inexpensive building substance, but has several disadvantages like cracking that allows corrosion, thus reducing its lifespan. To mitigate these complications, long-lasting microbial self-healing cement an alternative eco-friendly also actively repairs cracks. The present paper describes the detailed experimental investigation on compressive strength of mortars, mixed with six alkaliphilic bacteria, isolated from subsurface mica mines high alkalinity....
Extracellular matrix protein 1 (ECM1) can inhibit TGFβ activation, but its antifibrotic action remains largely unknown. This study aims to investigate ECM1 function and physical interaction with the profibrotic connective tissue growth factor (CTGF) in fibrosis ductular reaction (DR).
The liver maintains important homeostatic functions such as metabolism and detoxification. Failure to remove toxic intermediates can cause hepatic damage, fibrosis, even cancer development. This review focuses on acetaldehyde dehydrogenases (ALDHs), a group of key enzymes within the ALDH superfamily with ability convert highly reactive aldehyde substrates corresponding carboxylic acids in NAD(P)-dependent manners. These participate diverse array biological processes detoxification,...
Background: Fatty acids occur in nearly all living organisms as the important predominant constituents of lipids. While fatty have essentially same chemical nature, they are an extremely diverse group compounds. Materials and Methods: To test hypothesis, alkaliphiles isolates, Bacillus subtilis SVUNM4, licheniformis SVUNM8, methylotrohicus SVUNM9, Paenibacillus dendritiformis SVUNM11, were characterized compared using gas chromatography-mass spectrometry (GC-MS) analysis. Results: The...
Alternative medicine is available for those diseases which cannot be treated by conventional medicine. Ayurveda and herbal medicines are important alternative methods in the treatment done with extracts of different medicinal plants. This work concerned evaluation anti-stress bioactive compounds from ethanolic root extract Hemidesmus indicus.Gas chromatography Mass Spectrum studies used to identify present based on retention time, area. In order perform docking studies, Vasopressin model...
A crylamide (ACR) become a major public health con- cerns when it has detected in the daily consuming food products like fried bread, potato chips and all carbohydrate-rich foods those cooked at high temperature (i.e.˂ 200 о C) (Guyton John, 2006;Kaneko et al., 2008), chips/French fries, crisps biscuits, crackers breakfast cereals (Tareke 2002), using several fields including laboratories absorbed while occupational exposure (Meng 2001; Boettcher 2005), causes to generation of free radicals...
Archaeal group II chaperonins, also known as heat shock proteins (HSPs), are abundantly expressed in Sulfolobales. HSPα and HSPβ gene expression is upregulated during thermal shock. HSPs form large 18-mer complexes that assist folding nascent protecting resident stress. Engineered have been designed for industrial applications. Since temperature flux the geothermal habitats of Sulfolobales impacts intracellular temperature, it follows developed thermotolerance. However, despite low pH (i.e.,...
Abstract Ethnopharmological relevanceAnantapuram district is known for rich plant source and their traditional practices from long time by certain tribes different diseases. Despite of increase in acceptance medicines India, this indigenous knowledge about medicinal plants Anantapuram not adequately documented previously.MethodsExtensive was done past three years a total 66 species 64 genera 42 families were recorded. Interviews, Observations guided talks with 415 participants conducted to...
Abstract Crenarchaeal group II chaperonins (a.k.a., “heat shock” proteins, HSPs) are abundantly expressed in species of the family Sulfolobaceae . HSPα and HSPβ expression is upregulated during thermal shock. HSPs subunits larger octadecameric complexes that function to protect intracellular proteins stress. Engineered have been constructed with idea protecting enzymes industrial reactions. HSPβ-coh, a fusion protein comprised type 1 cohesin from Clostridium thermocellum was used for...