A5073621776- Atherosclerosis and Cardiovascular Diseases
- Analytical Chemistry and Chromatography
- Immune Cell Function and Interaction
- Mass Spectrometry Techniques and Applications
- Inflammasome and immune disorders
- Systemic Lupus Erythematosus Research
- Microfluidic and Capillary Electrophoresis Applications
- Immune Response and Inflammation
- Liver Diseases and Immunity
- Mycobacterium research and diagnosis
- Helicobacter pylori-related gastroenterology studies
- Microscopic Colitis
Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research
2021-2024
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is a biophysical technique well suited to the characterization of protein dynamics and protein–ligand interactions. In order accurately define rate exchange, HDX experiments require repeated measure deuterium incorporation into target across range time points. Accordingly, HDX-MS experiment automation, number automated systems for have been developed. The most widely utilized platforms all operate an integrated design, where robotic...
The immune cellular landscape from the gastric mucosa remains largely unknown despite its relevance in several inflammatory conditions. Human biopsies were obtained antrum, body and incisura 10 individuals to obtain lamina propria mononuclear cells that further characterized by spectral cytometry. Phenotypic hierarchical analyses identified a total of 52 different cell subsets within human revealing T-cells (> 60%) NK 20%) main populations. Within T-cells, CD4+ CD8+ equally represented with...