Yujie Hu

ORCID: 0000-0003-3369-5278
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About
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Research Areas
  • Glaucoma and retinal disorders
  • Cancer Immunotherapy and Biomarkers
  • Retinal Development and Disorders
  • Acute Kidney Injury Research
  • Immune cells in cancer
  • Cell Adhesion Molecules Research
  • Endometriosis Research and Treatment
  • Cellular Mechanics and Interactions
  • Cancer Cells and Metastasis
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Lung Cancer Diagnosis and Treatment
  • Berberine and alkaloids research
  • Plant-based Medicinal Research
  • Urban Transport and Accessibility
  • Pancreatic and Hepatic Oncology Research
  • Medical and Biological Ozone Research
  • Writing and Handwriting Education
  • Abdominal vascular conditions and treatments
  • Colorectal Cancer Screening and Detection
  • Cancer Genomics and Diagnostics
  • Blood donation and transfusion practices
  • Breast Implant and Reconstruction
  • Fermentation and Sensory Analysis
  • Respiratory and Cough-Related Research
  • Trigeminal Neuralgia and Treatments

Sun Yat-sen University
2025

Shanghai Jiao Tong University
2023-2024

Shanghai Sixth People's Hospital
2023-2024

Northwest University
2024

China United Network Communications Group (China)
2024

Cixian People's Hospital
2024

Beijing University of Chinese Medicine
2022-2023

Zhejiang Chinese Medical University
2022-2023

Chinese PLA General Hospital
2023

Xingtai University
2023

Abstract Background Accurately assessing the prognosis of bladder cancer patients after radical cystectomy has important clinical and research implications. Current models, based on traditional statistical approaches complex variables, have limited performance. We aimed to develop a machine learning (ML)-based prognostic model predict 5-year cancer-specific mortality (CSM) in undergoing cystectomy, compare its performance with current validated models. Methods Patients were selected from...

10.1186/s12885-025-13942-2 article EN cc-by BMC Cancer 2025-03-21

purpose. To determine the active site in Heparin II (HepII) domain of fibronectin that regulates outflow facility cultured anterior segments and disrupts actin cytoskeleton transformed human trabecular meshwork (TM-1) cells. methods. Outflow was determined by two-level, constant-pressure perfusion rhesus cynomolgus monkey eyes. One segment from each pair exchanged with either HepII or an integrin/syndecan binding peptide (IDAPS PPRARI) domain. assay changes cytoskeleton, TM-1 cells were...

10.1167/iovs.08-2143 article EN Investigative Ophthalmology & Visual Science 2009-01-01

Erchen decoction (ECD) is a common treatment prescribed in traditional Chinese medicine (TCM) clinics, which has remarkable efficacy the of obesity, fatty liver, hyperlipidemia, diabetes, and other diseases caused by phlegm. In this study, we investigated effect that ECD had on lipid metabolism induced high-fat diet C57BL/6 mice. Body weight, body length, abdominal circumference were detected. Blood content was measured via biochemical assay kit. The gene protein expression PPARγ LPL...

10.1155/2020/9102475 article EN cc-by Evidence-based Complementary and Alternative Medicine 2020-01-01

Chronic kidney disease (CKD) is an ongoing deterioration of renal function that often progresses to end-stage disease. In this study, we aimed screen and identify potential key genes for CKD using the weighted gene coexpression network (WGCNA) analysis tool. Gene expression data related were screened from GEO database, datasets GSE66494 GSE62792 obtained. After discrete samples, WGCNA was performed construct module, correlation between module calculated. The modules with a significant...

10.1155/2022/4615292 article EN cc-by Journal of Immunology Research 2022-05-04

Migraine is a major cause of disability worldwide, particularly in young adults and middle-aged women. Xiongshao Zhitong Recipe (XZR) traditional Chinese medicine prescription used for treating migraine, but its bioactive components therapeutic mechanisms remain unclear. We aimed to confirm the effect XZR on migraine determine possible mechanism XZR. Here, sensitive UHPLC-LTQ-Orbitrap MS assay was carried out analyze ingredients XZR, total 62 were identified, including coumarins, phenolic...

10.3389/fphar.2022.920201 article EN cc-by Frontiers in Pharmacology 2022-07-19

To investigate the expression of response gene to complement 32 (RGC32) in rat with acute kidney injury (AKI) and explore role RGC32 renal repair induced by ischemia reperfusion. Rats were randomly divided into two groups, including sham operation group (n = 48) reperfusion (IRI) 48). sacrificed following 2 h, 6 24 48 72 1 week (w), w, 4 w. The distribution tissue observed means immunohistochemistry. mean density images detected Image-Pro Plus was designated as representative levels....

10.3109/0886022x.2015.1120118 article EN Renal Failure 2015-12-10

Abstract Surgical site infections (SSIs) following radical mastectomy in breast cancer patients can significantly affect patient recovery and healthcare resources. Identifying understanding the risk factors for postoperative wound (PWIs) are crucial improving surgical outcomes. This retrospective study was conducted from June 2020 to 2023, including 23 who developed PWIs post‐radical a control group of 46 without such infections. Comprehensive data, variables as intraoperative blood loss,...

10.1111/iwj.14848 article EN cc-by-nc International Wound Journal 2024-04-01

The Staphylococcus aureus (S. aureus) SaeRS two-component system (TCS) regulates over 20 virulence factors. While its impact on chronic infection has been thoroughly discussed, role in the early stage of remains elusive. Since macrophages serve as primary immune defenders at onset infection, this study investigates influence macrophage functions and elucidates underlying mechanisms. Macrophage expression inflammatory chemotactic factors, phagocytosis, bactericidal activity against S. were...

10.1038/s41522-024-00576-8 article EN cc-by-nc-nd npj Biofilms and Microbiomes 2024-10-06

Hepatocyte nuclear factor 1alpha (HNF-1alpha) is a homeodomain-containing transcription and important in postnatal growth development mice. In the HNF-1alpha-deficient liver, expressions of large set hormone (GH)-responsive genes were significantly downregulated. By analyzing various HNF-1alpha mutant mice, we disclosed mechanism by which hepatic regulates expression GH-responsive that are crucial for development. We found required normal glucocorticoid receptor (GR) specifically livers. GR,...

10.1152/ajpgi.00081.2008 article EN AJP Gastrointestinal and Liver Physiology 2008-06-27

English Writing as a second language learner faces more cognitive, social, and emotional challenges. Students can improve their writing skills through creative writing. From this perspective, study examined the relationship between teaching behaviours (CTB) (ECW) role of self-efficacy (EWSE) (CSE) in multi-mediating relation. It also investigated whether there is any difference English-majoring students (EMS) non-English majoring (non-EMS). Participants included 478 university China. The...

10.1080/14790726.2023.2188223 article EN New Writing 2023-03-21
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