A5078771096- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Vascular Tumors and Angiosarcomas
- Oral and Maxillofacial Pathology
- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Cardiac tumors and thrombi
- Neurofibromatosis and Schwannoma Cases
- Spinal Fractures and Fixation Techniques
- Cancer Immunotherapy and Biomarkers
- Soft tissue tumor case studies
- CAR-T cell therapy research
- Immune Cell Function and Interaction
- Cervical and Thoracic Myelopathy
- Medical Imaging and Analysis
- Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Scoliosis diagnosis and treatment
- Spinal Hematomas and Complications
- Medical Imaging and Pathology Studies
- Immune cells in cancer
- Meningioma and schwannoma management
- Musculoskeletal pain and rehabilitation
- Urologic and reproductive health conditions
Saga University
2016-2025
Weatherford College
2024
Khon Kaen University
2024
Tokyo National Hospital
2024
Obayashi (Japan)
2024
National Cancer Center
2024
Kyushu University
2018-2023
National Cancer Centre Japan
2022
Pathological Society
2019
Fukuoka University
2017
Angiosarcoma is so rare, no reports on its epidemiology and prognosis using nationwide population-based data exist. The present study aimed to clarify the characteristics clinical outcomes of angiosarcoma National Cancer Registry (NCR) in Japan. We analyzed from 23,522 patients with soft-tissue sarcomas (STS), entered NCR 2016–2019 International Classification Diseases-Oncology, Third Edition cancer topography morphology codes. extracted demographics, tumor details, treatment, for each...
Despite the recent advances in cancer treatment, incidence of patients with spinal metastases continues to grow along total number patients. Spinal can significantly impair activities daily living (ADL) and quality life (QOL), compared other types bone metastases, as they are characterized severe pain paralysis caused by skeletal-related events. Reduced ADL also lead treatment limitations certain anticancer agents radiation therapy not compatible treatments; thus, leading a shorter...
Aims Phosphaturic mesenchymal tumour, mixed connective tissue variant (PMT‐MCT), is a tumour of uncertain differentiation, characterised by ‘smudgy/grungy’ calcification and vitamin D‐resistant phosphaturic osteomalacia. Fibroblast growth factor (FGF)23 recognised as reliable marker PMT‐MCT, but quantitative evaluation has never been performed. We reviewed cases tumour‐associated osteomalacia or histologically definitive PMT‐MCT without using histological, immunohistochemical genetic methods...
Myxofibrosarcoma (MFS) is a malignant fibroblastic/myofibroblastic neoplasm with the prominent myxoid area. It has clinical features of frequent local recurrence and occasional distant metastasis. Morphologically, MFS occasionally difficult to distinguish from undifferentiated pleomorphic sarcoma (UPS), especially in case high-grade MFS. Here, we reviewed histologic data 162 cases 43 UPS cases. was distinguished criterion 10% area as cutoff value. Overall, 52 (34.4%) 9 (20.9%) showed...
Abstract Background Chondrosarcoma (CS) is a rare malignant bone tumor exhibiting diverse histological features and clinical behaviors. This study aimed to investigate the epidemiological characteristics, features, prognostic factors, subtype-specific differences of CS in Japan using National Cancer Registry data. Methods We analyzed data from cases diagnosed between 2016 2019, calculating age-adjusted incidence, estimating overall survival, identifying factors through multivariate analysis....
The concept of minimally invasive spine therapy (MIST) has been proposed as a treatment strategy to reduce the need for overall patient care, including not only surgery (MISS) but also conservative and rehabilitation. To maximize effectiveness care in surgery, educational needs medical students, residents, rehabilitation can be enhanced by digital transformation (DX), virtual reality (VR), augmented (AR), mixed (MR), extended (XR), three-dimensional (3D) images holograms; wearable sensors,...
The phrase “skin as a mirror of internal medicine,” which means that the skin reflects many diseases organs, is well-known notion. Despite phenotypic differences between soft and hard bone, bone are highly associated. Skin consist fibroblasts osteoblasts, respectively, secrete collagen involved in synthesis, while Langerhans cells osteoclasts control turnover. Moreover, quality quantity may be modified by aging, inflammation, estrogen, diabetes, glucocorticoids. pathologically drugs,...
Abstract Myxoid liposarcoma (MLS) accounts for 20%‐30% of and the round cell component (RCC) is believed to be a specific poor prognostic factor. However, RCC assessment criteria are vaguely defined and, therefore, inconsistently employed by pathologists. In this study, we modified applied two established grading systems evaluate nuclear atypia (namely, World Health Organization/International Society Urological Pathology Fuhrman in renal carcinoma) 64 MLS cases. Detailed software‐based...
No previous reports have characterized national profiles of soft-tissue sarcoma overall. We examined the nationwide statistics for in Japan using data from population-based National Cancer Registry.
Abstract Giant cell tumor of bone (GCTB) is an intermediate malignant that locally aggressive and rarely metastasizes. Denosumab, which a receptor activator nuclear factor kappa B ligand (RANKL) inhibitor, can be used to treat GCTB. We focused on potential immunotherapy for GCTB investigated the microenvironment Programmed death-ligand 1 (PD-L1) indoleamine 2,3-dioxygenase (IDO1) expression signal-regulatory protein alpha (SIRPα), forkhead box P3 (FOXP3), cluster differentiation 8 (CD8)...