A5091224699- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- COVID-19 epidemiological studies
- Mobile Health and mHealth Applications
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Economic and Financial Impacts of Cancer
- Animal Virus Infections Studies
- Palliative Care and End-of-Life Issues
- Health Literacy and Information Accessibility
- Influenza Virus Research Studies
- Venous Thromboembolism Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Data-Driven Disease Surveillance
- Chronic Disease Management Strategies
- Lymphoma Diagnosis and Treatment
- SARS-CoV-2 detection and testing
- Health Systems, Economic Evaluations, Quality of Life
- Hepatitis C virus research
- Adolescent Sexual and Reproductive Health
- Social Media in Health Education
- Biosimilars and Bioanalytical Methods
- Rheumatoid Arthritis Research and Therapies
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Diagnosis and Treatment
CVS Health (United States)
2022-2025
Health Outcomes Solutions (United States)
2024
Aetna (United States)
2022-2023
Citizen (Japan)
2023
Einstein Healthcare Network
2019-2020
Einstein Medical Center Philadelphia
2018-2020
Naval Health Research Center
2014-2019
San Diego State University
2014
University of California, San Diego
2014
Importance The incidence of arterial thromboembolism and venous in persons with COVID-19 remains unclear. Objective To measure the 90-day risk patients hospitalized before or during vaccine availability vs influenza. Design, Setting, Participants Retrospective cohort study 41 443 (April-November 2020), 44 194 (December 2020-May 2021), 8269 influenza (October 2018-April 2019) US Food Drug Administration Sentinel System (data from 2 national health insurers 4 regional integrated systems)....
Importance Head-to-head safety comparisons of the mRNA vaccines for SARS-CoV-2 are needed decision making; however, current evidence generalizes poorly to older adults, lacks sufficient adjustment, and inadequately captures events shortly after vaccination. Additionally, no studies date have explored potential variation in comparative vaccine across subgroups with frailty or an increased risk adverse events, information that would be useful tailoring clinical decisions. Objective To compare...
Introduction Co-administering COVID-19 and influenza vaccines is recommended by public health authorities intended to improve uptake convenience; however, the extent of vaccine co-administration largely unknown. Investigations into are needed describe compliance with newer recommendations identify potential gaps in implementation co-administration. Methods A descriptive, repeated cross-sectional study between September 1, 2021 November 30, (Period 1) 2022 2) was conducted. This included...
Background Little is known about whether people who use both tobacco and cannabis (co-use) are more or less likely to have mental health disorders than single substance users non-users. We aimed examine associations between of and/or with anxiety depression. Methods analyzed data from the COVID-19 Citizen Science Study, a digital cohort study, collected via online surveys during 2020–2022 convenience sample 53,843 US adults (≥ 18 years old) nationwide. Past 30-day was self-reported at...
This cohort study examines time trends in officially reported SARS-CoV-2 case counts and unreported home test positivity.
COVID-19 booster vaccines are highly effective at reducing severe illness and death from COVID-19. Research is needed to identify whether racial ethnic disparities observed for the primary series of persist vaccinations how those may vary by other characteristics. We aimed measure differences in vaccine receipt among U.S. Medicare beneficiaries characterize potential variation demographic conducted a cohort study using CVS Health Walgreens pharmacy data linked claims. included...
The U.S. Food and Drug Administration (FDA) Biologics Effectiveness Safety (BEST) Initiative conducts active surveillance of adverse events special interest (AESI) after COVID-19 vaccination. Historical incidence rates (IRs) AESI are comparators to evaluate safety.We estimated IRs 17 in six administrative claims databases from January 1, 2019, December 11, 2020: Medicare for adults ≥ 65 years commercial (Blue Health Intelligence®, CVS Health, HealthCore Integrated Research Database, IBM®...
Monovalent booster/additional doses of COVID-19 vaccines were first authorized in August 2021 the United States. We evaluated real-world effectiveness receipt a monovalent dose vaccine compared with receiving primary series without dose. Cohorts individuals after complete identified 2 administrative insurance claims databases (Optum, CVS Health) supplemented state immunization information system data between and March 2022. Individuals but one-to-one matched to boosted on calendar date,...
Few studies have examined how the absolute risk of thromboembolism with COVID-19 has evolved over time across different countries. Researchers from European Medicines Agency, Health Canada, and United States (US) Food Drug Administration established a collaboration to evaluate arterial (ATE) venous (VTE) in 90 days after diagnosis ambulatory (eg, outpatient, emergency department, nursing facility) setting seven countries North America (Canada, US) Europe (England, Germany, Italy,...
Abstract Background Following the COVID-19 pandemic, little is known about timing of vaccination against both influenza (flu) and during peak respiratory illness season in United States. The study objective to examine coadministration rates flu vaccines two most recent seasons explore sociodemographic clinical characteristics associated with timing.Table 1.Monthly Coadministration Rates Flu COVD-19 Vaccines Season 1 2 Methods A retrospective cohort was conducted adults aged 18-64 years from...
Lyme disease (LD) is the most common vector-borne in United States, though traditional LD surveillance underestimates burden of disease. We validated algorithms for early localized and disseminated LD, with without LD-specific diagnosis codes, states high incidence their neighboring low incidence. identified cohorts potential incident cases administrative insurance claims data, October 2015-October 2023, 1 national regional insurer. Three were studied: a primary algorithm an code indicated...
With data from 2 US claims databases (Optum, CVS Health) supplemented with Immunization Information System COVID-19 vaccine records, we evaluated overall and time-specific effectiveness (VE) of an initial primary series for 3 monovalent vaccines—BNT162b2, mRNA-1273, JNJ-7836735—in adults (18-64 years). Vaccinated individuals were matched to unvaccinated comparators, estimated VE against any medically diagnosed hospital/emergency department (ED)-diagnosed COVID-19. Additionally, by era...
ABSTRACT Purpose Active monitoring of health outcomes after COVID‐19 vaccination provides early detection rare post‐licensure. We evaluated following bivalent Pfizer‐BioNTech (BNT162b2) and Moderna (mRNA‐1273.222) in the United States. Methods Multiple were monitored monthly from August 2022 to July 2023 four administrative claims databases (CVS Health, Carelon Research, Optum, Medicare). The study included individuals 6 months older who received a BNT162b2 or mRNA‐1273.222 during period met...
COVID-19 increased the prevalence of clinically significant anxiety in United States. To investigate contributing factors we analyzed anxiety, reported online via monthly Generalized Anxiety Disorders-7 (GAD-7) surveys between April 2020 and May 2022, association with self-reported worry about health effects COVID-19, economic difficulty, personal experience, subjective social status. 333,292 from 50,172 participants (82% non-Hispanic white; 73% female; median age 55, IQR 42–66) showed high...
Patients with cancer often require acute hospitalizations, many of which are unplanned. These hospitalizations have been shown to increase in frequency near the end life. The American College Physicians recommends that goals-of-care (GOC) discussions be initiated early for metastatic cancers. We hypothesized discussing GOC during hospitalization could help reduce readmissions. Our aim was examine association between timing discussion, length hospital stay, and time readmission.We conducted a...
Abstract Active monitoring of health outcomes after COVID-19 vaccination provides early detection rare post-licensure. Objective To evaluate following bivalent Pfizer-BioNTech (BNT162b2) and Moderna (mRNA-1273.222) among individuals 6 months older in the United States. Design Monthly from August 2022 to July 2023 four administrative claims databases. Descriptive analyses monitored vaccine uptake, outcome counts coadministration influenza vaccines. Sequential tested for elevated risk each a...
COVID-19 vaccines are authorized for use in children the United States; real-world assessment of vaccine effectiveness is needed. This study's objective was to estimate receiving a complete primary series monovalent BNT162b2 (Pfizer-BioNTech) US children.
To measure the 90 day risk of arterial thromboembolism and venous among patients diagnosed with covid-19 in ambulatory (ie, outpatient, emergency department, or institutional) setting during periods before vaccine availability compare results to influenza.Retrospective cohort study.Four integrated health systems two national insurers US Food Drug Administration's Sentinel System.Patients when vaccines were unavailable (period 1, 1 April-30 November 2020; n=272 065) available 2, December...
The prevalence of disabilities is rising steadily, reflecting an aging population and increasing burden chronic conditions affecting quality life. There are scant national data on the disability among individuals with obstructive pulmonary disease (COPD). main objective was to estimate common US-based diagnosed COPD.Data from BRFSS, a telephone survey examining health-related behaviors in 2016-2017 were analyzed. study consisted self-reported COPD (N = 38352 2016 N 35423 2017). hearing,...
ABSTRACT Objective To evaluate febrile seizure risk following monovalent COVID-19 mRNA vaccination among children aged 2-5 years. Methods The primary analysis evaluated who had a outcome in the 0-1 days vaccination. A self-controlled case series was performed three commercial insurance databases to compare of interval (0-1 days) control (8-63 days). exposure interest receipt dose 1 and/or 2 vaccinations. day interval). conditional Poisson regression model used rates and intervals estimate...
Trastuzumab is an antihuman epidermal growth factor receptor 2 monoclonal antibody used to treat breast and other cancers. biosimilars were approved in the United States beginning 2017. Utilization information on these limited.