A5046821463- Dysphagia Assessment and Management
- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Child Nutrition and Feeding Issues
- Salivary Gland Disorders and Functions
- Oral health in cancer treatment
- Antifungal resistance and susceptibility
- Temporomandibular Joint Disorders
- Esophageal and GI Pathology
- Sleep and related disorders
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
- Health and Wellbeing Research
- Obstructive Sleep Apnea Research
- HIV/AIDS oral health manifestations
- BRCA gene mutations in cancer
- Olfactory and Sensory Function Studies
- Head and Neck Cancer Studies
- Antimicrobial Peptides and Activities
- Tracheal and airway disorders
- Advanced Glycation End Products research
- Geriatric Care and Nursing Homes
- Dental Erosion and Treatment
- Pharmacological Effects and Toxicity Studies
- Advanced Breast Cancer Therapies
Hiroshima University
2012-2025
National Cancer Center
2022
Weatherford College
2022
Tokyo National Hospital
2022
Hara K, Ohara M, Hayashi I, Hino T, Nishimura R, Iwasaki Y, Ogawa Ohyama Sugiyama Amano H. The green tea polyphenol (−)‐epigallocatechin gallate precipitates salivary proteins including alpha‐amylase: biochemical implications for oral health. Eur J Oral Sci 2012; 120: 132–139. © 2012 Green is a popular drink throughout the world, and it contains various components, (EGCG). Tea interacts with saliva upon entering mouth, so interaction between EGCG interested us, especially respect to...
Introduction: Next-generation sequencing (NGS) is commonly used in clinical practice to decide treatment based on genomic information. This study was performed optimize the proportion of actionable gene profiling and genetic alterations breast cancer at one centers Japan. Methods: Patients with who reported NGS results Japan from August 2019 December 2023 were retrospectively investigated by reviewing their electronic medical records. examined using OncoGuideTM NCC Oncopanel System,...
Objectives Swallowing function and oral-related quality of life (QOL) are important factors for maintaining general health. However, few studies have investigated the association between both among community-dwelling older adults. This cross-sectional study examined subjective swallowing QOL adults.Methods A questionnaire survey was conducted by mail in January 2022 men women 47 Japanese prefectures. included 552 aged ≥ 65 years with no missing data (93.7% response rate). Information...
Background/Objectives: Nisin A, an antimicrobial peptide produced by Lactococcus lactis, primarily shows activity against Gram-positive bacteria, with efficacy increased when used in combination drug. On the other hand, oral candidiasis, caused Candida, occurs immunocompromised patients and requires antifungal therapy. However, drug-resistant Candida strains are increasing worldwide, leading to serious problems. Methods: To examine effects of nisin A species, we investigated combined drugs...
ABSTRACT Background Several studies have examined the impact of tooth loss on nutrient intake, yielding mixed results. Objectives This cross‐sectional study aimed to investigate association among number teeth present, intake and food group consumption in Japanese adults with no history four major diseases (diabetes, cancer, heart disease stroke). Methods Data were obtained from baseline survey Japan Multi‐Institutional Collaborative Cohort conducted Shizuoka Daiko areas. Participants...
Purpose: Umami reportedly promotes salivation. We aimed to investigate the effects of taste stimuli on slow and fast salivary secretion in humans using umami, sweet, sour stimuli. Methods: Eight healthy women participated between 14:00 15:00, taking circadian rhythm into account. The types concentrations solutions were glutamic acid (1.7 × 10−3 M), inosinic (9.8 guanylic M) for umami stimulation, citric (6.5 acidity sucrose (1.6 10−2 sweetness stimulation. First, unstimulated flow rate was...
Drug-resistant opportunistic infections may cause health problems in immunocompromised hosts. Representative microorganisms of the oral cavity are Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans. We investigated prevalence drug-resistant elderly adults receiving follow-up examinations after primary treatment cancer. Oral were collected from patients satisfactorily treated for cancer (defined as good outcomes to date) a group healthy (controls). After identification...
The association between oral health and systemic disease is recognized in the literature. present study aimed to clarify bacteria on tongue dorsum factors associated with middle‑aged elderly patients. bacterial numbers, status was preliminarily investigated 70 patients (mean age, 69.5 years; range, 45‑92 years) who visited Department of Oral Health, Hiroshima University Hospital (Hiroshima, Japan). 16S ribosomal RNA gene employed quantitate numbers using real‑time polymerase chain reaction...
Abstract This study aimed to clarify the association of daily physical activity and leisure-time exercise with risk dysphagia in community-dwelling Japanese older adults using a questionnaire-based survey. We analyzed 3070 participants (1657 men, 1413 women; age 66 ± 4 years [mean SD]) Shizuoka Daiko studies within Multi-Institutional Collaborative Cohort study. used Dysphagia Risk Assessment for Community-dwelling Elderly questionnaire assess International Physical Activity Questionnaire...
We previously reported that oral herpesviruses, such as Epstein-Barr virus (EBV), are associated with periodontitis. However, the relationship between EBV or dual and Porphyromonas gingivalis infections periodontal inflammation severity remains unclear. conducted this study to determine P prevalence inflamed surface area (PISA) in middle-aged older adults. analyzed 205 patients (median age, 70 years) who visited Hiroshima University Hospital. Tongue swab samples were used investigate...
Exploring the effects of swallowing function on sleep quality could provide valuable insights into potential impact reduced sleep. However, pertinent studies are limited. Therefore, this study aimed to investigate relationship between dysphagia risk and health in community-dwelling older adults.
The effects of oral health on mortality have been reported; however, the association between and Oral Health-Related Quality Life (OHQOL) is unknown. We investigated effect OHQOL total in a cohort consisting dentists.In this study, we analyzed data from Longitudinal Evaluation Multi-phasic, Odonatological Nutritional Associations Dentists study. conducted baseline survey general factors. called for 31,178 participants collected responses 10,256 participants. followed up with 10,114 (mean age...
The aim of this study was to clarify the association between oral Candida detection and dependency status older people. This included 31 people aged ≥70 years who had a certified need for long-term care or support received in local day center; it also 27 independent patients visited Hiroshima University Hospital. Oral detected by polymerase chain reaction using swab samples from tongue surface. moisture significantly reduced dependent people, compared with (p = 0.003). There weak negative...
Other SectionsAbstractIntroductionThe Past and Current Status of Dental Hygienists in JapanConclusionConflict interestEthical approvalAuthor contributionsReference
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Few studies have evaluated masticatory ability and habits in relation to physical function. This study aimed investigate the association of function with both habits. In this cohort study, we followed up 146 community-dwelling older adults aged 65–84 years for 1 year. Physical domain scores on Kihon Checklist were used assess Masticatory was examined using objective measurements self-administered questionnaires. Data obtained The Mann–Whitney U test analyze between as exposures; logistic...
Dental caries and periodontal disease are typical oral diseases frequently observed in patients with renal diseases. Tooth loss is an outcome of dental disease, the number existing teeth indicator health status. However, association between end-stage kidney (ESKD) has not been investigated detail. This study aimed to investigate status, expressed by teeth, ESKD. We analyzed data from second survey Longitudinal Evaluation Multi-phasic, Odontological, Nutritional Associations Dentists, a...
Background: Legal regulations and fees have been established in Korea to provide visiting oral health care services individuals with long-term insurance (LTCI).However, beneficiaries of this service are very limited.Therefore, improve the Korean system we propose a comparative analysis Japanese system.Methods: This study is descriptive based on secondary data, such as statistics, laws, record forms from Japan.The most recent institutional documents were obtained through Google search.The...