- Carbohydrate Chemistry and Synthesis
- Glycogen Storage Diseases and Myoclonus
- Metabolism and Genetic Disorders
- Glycosylation and Glycoproteins Research
- Enzyme Structure and Function
- Folate and B Vitamins Research
- Biochemical and Molecular Research
- Ion channel regulation and function
- Photoreceptor and optogenetics research
- Connexins and lens biology
- Computational Drug Discovery Methods
- Cancer-related gene regulation
- S100 Proteins and Annexins
- RNA modifications and cancer
- Diet and metabolism studies
- Metal complexes synthesis and properties
- Polymer Surface Interaction Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Hippo pathway signaling and YAP/TAZ
- Porphyrin Metabolism and Disorders
- Health, Environment, Cognitive Aging
- Biochemical effects in animals
- Lipid metabolism and disorders
- Mobile Health and mHealth Applications
- Nanoparticle-Based Drug Delivery
Jining First People's Hospital
2019-2023
People's Liberation Army 401 Hospital
2023
Chinese People's Liberation Army
2023
Guangzhou University of Chinese Medicine
2022
Foshan Maternity and Child Health Care Hospital
2022
Southern Medical University
2022
Xuzhou University of Technology
2017
Nanjing Medical University
2014
Nankai University
2007-2008
A multifunctional nanocarrier with multilayer core–shell architecture was prepared by alkaline coprecipitation of ferric and ferrous ions in the presence a triblock copolymer, methoxy poly(ethylene glycol)-block-poly(methacrylic acid)-block-poly(glycerol monomethacrylate) (denoted MPEG-b-PMAA-b-PGMA), aqueous solution. The core is superparamagnetic Fe3O4 nanoparticle, on which PGMA block copolymer attached. PMAA forms inner shell MPEG outermost shell. anticancer agent adriamycin (ADR), as...
Two new heterodimeric sesquiterpenes, sterhirsutins C (1) and D (2), along with eight sesquiterpenoid derivatives, E–-L (3–10), were isolated from the culture of Stereum hirsutum. The absolute configuration 1 was assigned by a single-crystal X-ray diffraction experiment. Compounds 2 possessed an unprecedented chemical skeleton 5/5/5/6/9/4 fused ring system. Compound 10 is first sesquiterpene coupled xanthine moiety. 1–10 showed cytotoxicity against K562 HCT116 cell lines. 9 induced autophagy...
Precursor particles, monodisperse magnetic microspheres with diameter of 0.52 µm, were produced by deposition Fe3O4 nanoparticles within crosslinked poly(acrylic acid) prepared distillation–precipitation copolymerization. Subsequently, atom transfer radical polymerization (ATRP) initiators coupling the amino group ethanolamine carboxyl on precursor particles followed esterification hydroxyl 2-bromoisobutyryl bromide. tert-Butyl acrylate, glycidyl methacrylate and styrene initiated...
Abstract Cognitive impairment induced by postoperative pain severely deteriorates the rehabilitation outcomes in elderly patients. The present study focused on relationship between microglial exosome miR‐124‐3p hippocampus and cognitive pain. model was constructed intramedullary nail fixation after tibial fracture. Morphine intraperitoneally carried out for analgesia. Morris water maze tests were to evaluate impairment, while mRNA levels of neurotrophic factors (BDNF, NG) neurodegenerative...
Respiratory syncytial virus (RSV), a member of Paramyxoviridae family is responsible for bronchiolitis and pneumonia. The present study investigated anti-viral anti-inflammatory activities jatrophone against RSV-infection in pulmonary epithelial cells vitro mice model vivo. changes viabilities RSV infected by treatment were determined MTT assay. fluorescence associated with production ROS was evaluated microscopy using H2DCFDA dye. IFN-γ secreting detected BALF stimulation phorbol myristate...