A5068624749- SARS-CoV-2 and COVID-19 Research
- Genomics and Phylogenetic Studies
- Bacteriophages and microbial interactions
- Mycotoxins in Agriculture and Food
- Plant Pathogens and Fungal Diseases
- Animal Virus Infections Studies
- Plant-Microbe Interactions and Immunity
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Viral gastroenteritis research and epidemiology
- Plant Pathogenic Bacteria Studies
- CRISPR and Genetic Engineering
- Plant Disease Resistance and Genetics
- Vibrio bacteria research studies
- Microbial Community Ecology and Physiology
- Antibiotic Resistance in Bacteria
- vaccines and immunoinformatics approaches
- Genetic Associations and Epidemiology
- Genomics and Rare Diseases
- Microbial infections and disease research
- Enzyme Production and Characterization
- Pharmaceutical and Antibiotic Environmental Impacts
- Wheat and Barley Genetics and Pathology
- Amyotrophic Lateral Sclerosis Research
- Infections and bacterial resistance
Centre Hospitalier Universitaire de Tours
2024
Mohammed V University
2017-2024
Génétique, Diversité, Écophysiologie des Céréales
2018-2022
Université Clermont Auvergne
2018-2022
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2020-2022
In late December 2019, an emerging viral infection COVID-19 was identified in Wuhan, China, and became a global pandemic. Characterization of the genetic variants SARS-CoV-2 is crucial following evaluating it spread across countries. this study, we collected analyzed 3,067 genomes isolated from 55 countries during first three months after onset virus. Using comparative genomics analysis, traced profiles whole-genome mutations compared frequency each mutation studied population. The...
The COVID-19 pandemic has been ongoing since its onset in late November 2019 Wuhan, China. Understanding and monitoring the genetic evolution of virus, geographical characteristics, stability are particularly important for controlling spread disease especially development a universal vaccine covering all circulating strains. From this perspective, we analyzed 30,983 complete SARS-CoV-2 genomes from 79 countries located six continents collected 24 December 2019, to 13 May 2020, according...
Abstract In late December 2019, an emerging viral infection COVID-19 was identified in Wuhan, China, and became a global pandemic. Characterization of the genetic variants SARS-CoV-2 is crucial following evaluating it spread across countries. this study, we collected analyzed 3,067 genomes isolated from 55 countries during first three months after onset virus. Using comparative genomics analysis, traced profiles whole-genome mutations compared frequency each mutation studied population. The...
Carbapenem-resistant Acinetobacter baumannii has recently been defined by the World Health Organization as a critical pathogen. The aim of this study was to compare clonal diversity and carbapenemase-encoding genes A. isolates collected from colonized or infected patients hospital environment in two intensive care units (ICUs) Morocco.The patient environmental sampling carried out medical surgical ICUs Mohammed V Military teaching March August 2015. All recovered clinical samples, were...
Fusarium graminearum, the primary cause of head blight (FHB) in small-grain cereals, demonstrates remarkably variable levels aggressiveness its host, producing different infection dynamics and contrasted symptom severity. While secreted proteins, including effectors, are thought to be one essential components aggressiveness, our knowledge intra-species genomic diversity F. graminearum is still limited. In this work, we sequenced eight European strains contrasting characterize their...
Fusarium graminearum, the main causal agent of Head Blight (FHB), is one most damaging pathogens in wheat. Because complex organization wheat resistance to FHB, this pathosystem represents a relevant model elucidate molecular mechanisms underlying plant susceptibility and identify their drivers, pathogen's effectors. Although F. graminearum catalog effectors has been well characterized at genome scale, planta studies are needed confirm effective accumulation host tissues role during...
Abstract The COVID-19 pandemic has been ongoing since its onset in late November 2019 Wuhan, China. Understanding and monitoring the genetic evolution of virus, geographical characteristics, stability are particularly important for controlling spread disease especially development a universal vaccine covering all circulating strains. From this perspective, we analyzed 30,983 complete SARS-CoV-2 genomes from 79 countries located six continents collected December 24, 2019, to May 13, 2020,...
Genetic variations in the human genome represent differences DNA sequence within individuals. This highlights important role of whole sequencing which has become keystone for precision medicine and disease prediction. Morocco is an hub studying population migration mixing history. study presents analysis 3 Moroccan genomes; variant revealed 6 379 606 single nucleotide variants (SNVs) 1 050 577 small InDels. Of those identified SNVs, 219 152 were novel, with 1233 occurring coding regions,...
Here, we report the draft genome sequences of six severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains. SARS-CoV-2 is responsible for COVID-19 pandemic, which started at end 2019 in Wuhan, China. The isolates were obtained from nasopharyngeal swabs Moroccan patients with COVID-19. Mutation analysis revealed presence spike D614G mutation all genomes, widely present several genomes around world.
Fusarium graminearum is a major fungal pathogen that induces head blight (FHB), devastating disease of small-grain cereals worldwide. This announcement provides the whole-genome sequence highly virulent and toxin-producing French isolate, MDC_Fg1.
Ending COVID-19 pandemic requires a collaborative understanding of SARS-CoV-2 and mechanisms. Yet, the evolving nature coronaviruses results in continuous emergence new variants virus. Central to this is need for monitoring system able detect potentially harmful virus real-time. In manuscript, we present International Database Variations (IDbSV), result ongoing efforts curating, analyzing, sharing comprehensive interpretation SARS-CoV-2's genetic variations variants. Through user-friendly...
Abstract The SARS-CoV-2 identified as coronavirus species associated with severe acute respiratory syndrome. At the time of writing, genetic diversity Moroccan strains is poorly documented. present study aims to analyze and identify variants fortyeight collected from mid-March end May prediction their possible sources. Our results revealed 108 mutations in SARS-CoV-2, 50% were non-synonymous seven genes (S, M, N, E, ORF1ab, ORF3a, ORF8) variable frequencies. Remarkably, eight predicted have...
ABSTRACT This report describes the whole-genome shotgun sequences of two multidrug-resistant Acinetobacter baumannii strains, ABE8_07 and ABE12_M, isolated from a Moroccan hospital floor. These genome will initiate study characterization in Morocco.
Here, we report the draft genome sequence of Stenotrophomonas maltophilia MDMC339, a strain able to survive in difficult conditions imposed by Merzouga desert. The analyzed contains 4,788,525 bp with 4,262 genes coding for proteins, including several related stress.
ABSTRACT Here, we describe the annotated genome sequence of Mycobacterium tuberculosis MTB13_M. The organism was isolated from a sputum sample in Morocco.
Tuberculosis is a contagious disease that usually attacks the lungs but sometimes other parts of body, such as kidneys, glands, and bones. It an endemic major public health problem in Morocco. transmitted through airways via inhalation microdroplets containing Mycobacterium tuberculosis We present here whole-genome shotgun sequences three multidrug-resistant M. strains isolated from
We report the draft genome sequences of three Pseudomonas chengduensis strains isolated from sand dunes Merzouga (MDMC17 strain) and Erg Lihoudi (MDMC216 MDMC224 strains) regions in Moroccan desert. These bacteria are able to tolerate harsh environmental conditions desert ecosystem.
We report the draft genome sequences of Enterobacter hormaechei subsp. xiangfangensis strains MDMC82 and MDMC76, which were isolated from sand dunes Merzouga desert in Moroccan Sahara. These bacteria are able to tolerate harsh environmental conditions desert.
Mycobacterium tuberculosis is known to cause pulmonary and extrapulmonary tuberculosis. In Morocco, the spread of multidrug-resistant (MDR) (TB) has become a major challenge. Here, we announce draft genome sequences two strains, MTB1 MTB2, isolated from patients with in describe variants associated drug resistance.