How the routine laboratory tests change in terms of coronavirus disease 2019 (COVID-19) was retrospectively analyzed a large group patients. Biochemical, hematological and inflammatory variables totaly 555 (n = 532 non-intensive care unit (non-ICU), n 23 ICU) patients diagnosed with COVID-19 were accessing them through information system. White blood cell (WBC), neutrophil (NEU), platelet ratio, to lymphocyte ratio (NLR), derived NLR (d-NLR), aspartate aminotransferase, urea, creatine kinase...

Coronavirus disease 2019 (COVID-19) triggers important changes in routine blood tests. In this retrospective case-control study, biochemical, hematological and inflammatory biomarkers between March 10, 2020, November 30, 2020 from 3969 COVID-19 patients (3746 the non-intensive care unit (non-ICU) group 223 ICU group) were analyzed by dividing into three groups as spring, summer autumn. non-ICU group, lymphocyte to monocyte ratio was lower autumn than other two seasons neutrophil higher...

Abstract Isotretinoin is an effective treatment against acne vulgaris, but it also causes many side effects during and after the treatment. The relationship between changes in levels of plasma trace elements patients with AV 3 months isotretinoin was investigated study. Plasma samples 35 were collected before Samples analyzed by Inductively Coupled Plasma–Mass Spectrometer. After treatment, phosphorus, magnesium, zinc increased statistically, while level potassium decreased ( p < 0.05)....

Objective: Gestational diabetes mellitus is a common disorder of carbohydrate metabolism, with onset or first recognition during pregnancy, resulting in hyperglycemia variable severity. Insulin resistance and chronic subclinical inflammation are the underlying mechanisms disease. Soluble interleukin-2 receptor, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio markers inflammatory disease processes such as type 1 2 mellitus, hepatitis, neoplasms.Study Design: In our study, we...

Due to the lack of diagnostic efficiency serum creatinine in acute kidney injury (AKI), there is a pressing need develop novel markers. Therefore, this study, we evaluated myo-inositol oxygenase (MIOX), neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C terms their applicability diagnosis AKI.We enrolled total 39 AKI patients 38 healthy controls study. We compared levels MIOX, NGAL between two groups.We found that concentrations creatinine, blood-urea nitrogen, MIOX were higher...

We aimed to investigate whether a low intrarenal pressure provided by ureteral access sheath (UAS) use had positive effect on the prevention of acute kidney injury through evaluation myo-inositol oxygenase (MIOX). The patients were divided into two groups according 9.5/11.5-Fr UAS was used during retrograde surgery (RIRS): group and non-UAS group. RIRS performed under gravity irrigation manual pumping not used. For measurement MIOX, 5 cc blood samples taken from preoperatively four hours...

This study evaluated the therapeutic efficacy of heparin and methylprednisolone in treatment ischaemic reperfusion (IR) injury testis. Twenty-four male Sprague-Dawley rats were allocated equally into three groups eight animals each. The left testes rotated 720° for 2 h torsion-detorsion group. Rats underwent same surgical procedure as group but also given (group II) or III) by an intraperitoneal route 30 min prior to detorsion. Left orchiectomy was performed all from each experimental animal...

Objective: Benign paroxysmal positional vertigo (BPPV) is characterized by recurrent attacks of caused head movements. It occurs as a result otoconia falling into the semicircular canal. Calcium and 25 hydroxyvitamin D [25(OH)D] metabolism in inner ear play an important role formation degeneration. Our aim this study was to investigate relationship between 25(OH)D levels BPPV. Methods: This retrospective, case–controlled included 52 patients with posterior canal BPPV controls aged 18 80...

Although the pathophysiology of fibromyalgia has not yet been fully clarified, inflammation and endothelial dysfunction have suggested to occur in patients with fibromyalgia. In recent years, endocan reported as an important biomarker for dysfunction. this study, we investigated mechanism by measuring serum levels patients.The samples collected from 37 female diagnosed first time 43 healthy women were analysed terms laboratory parameters, values two groups compared.In patient group, level...

A 50 g glucose challenge test (GCT) is recommended for screening all pregnant women gestational diabetes mellitus. In this study, the effect of GCT on thiol/disulfide balance was investigated.One-hundred that underwent a at 24-28 weeks gestation (63 positive and 37 negative results) were evaluated in terms serum samples hours 0 1.Compared to baseline values (hour 0), after load 1), thiol native thiol/total (p < 0.0001) GCT-positive reduced whereas glucose, disulfide, disulfide/native thiol,...

Aim: Glaucoma is an optic neuropathy causing progressive impairment of visual functions. We aimed to assess the alterations in thiol-disulfide homeostasis and serum ischemia modified albumin (IMA) levels, which are determinants antioxidant status, patients with primary open-angle glaucoma (POAG). Material Method: A total 140 eyes from 70 POAG 174 87 healthy, control cases were included study. All study participants underwent a complete ophthalmic evaluation. Alterations IMA levels measured...

Our aim in this study is to examine the effects of α-tocopherol (AT) on rats with aspiration pneumonitis induced bile acids (BAs). The animals were divided four groups, namely saline group (n = 7), + AT BA and 7). Saline groups aspirated intratracheally 1 ml/kg acids, respectively. was given at 20 mg/kg/day dosage for 7 days groups. days. Malondialdehyde (MDA), Clara cell protein 16 (CC-16), catalase (CAT), superoxide dismutase (SOD), as well peribronchial inflammatory infiltration, alveolar...

&lt;b&gt;Introduction&lt;/b&gt; There is increasing evidence that vitamin D affects insulin and glucose metabolism, a low status suspected to be risk factor for impaired tolerance, resistance so polycystic ovary syndrome (PCOS), but there no suggest relationship between A, B&lt;SUB&gt;12&lt;/SUB&gt;, C, folate, zinc (Zn) PCOS in the literature. We aimed investigate levels of vitamins C association D, folate level hormonal-biochemical parameters PCOS.&lt;br /&gt; &lt;b&gt;Material methods:...

Objective: Coronavirus disease-2019 (COVID-19) is a disease that can progress with hypoxemia and severe respiratory distress in some patients.The oxyhemoglobin dissociation curve (ODC) critical to understanding the effects of O2 exchange.This study aimed evaluate relationship between ODC oxygen-carrying capacity hemoglobin (Hb) COVID-19 patients. Materials Methods:In study, ODCs were created by examining data obtained from arterial blood gas analyses 686 intensive care unit (ICU) non-ICU...

Abstract Purpose: Acute kidney injury (AKI) is a severe disease carrying high morbidity and mortality. An ischemic process, at the cellular level, has been detected prior to full-blown AKI. elevated modified albumin (IMA) was also found be increased fast several minutes following an process in body. In this connection, we have investigated, advance, changes of IMA concentrations patients with possible Methods: other biochemical haematological parameters were measured sera thirty nine AKI...

Abstract Background: It is necessary to use an effective vaccine end the COVID-19 pandemic.CoronaVac used in our country and we aimed examine level of antibody development after theseconddose. Methods: This a retrospective, cross-sectional research. The dataof people, who applied university hospital between January March 2021, were analyzed. Those had SARS-CoV-2 IgG IgMmeasurement previous two weeks before CoronoVac vaccine, those both found negative IgM measurement seconddose CoronaVac...

To investigate the effect of retrograde intra-renal surgery (RIRS) on kidneys using myo-inositol oxygenase (MIOX) enzyme. MIOX is a renal tubular-specific novel marker for early diagnosis acute kidney injury.A total twenty seven individuals that had undergone RIRS to treat stones were included in study. Biochemical tests performed serum samples collected immediately before (hour 0) and at 6th 24th hours after surgery.The creatinine value hour 6 was lower than baseline (p = 0.0305). Cystatin...

D iabetes mellitus refers to a metabolic disease with en- tire or partial absence of insulin resistance insulin.The damages the retina, kidney, peripheral, and autonomic nerves are caused by structural functional changes occurring in microvascular compartments.The complications diabetes include retinopathy, nephropathy, neuropathy.The development is related hyper-glycemia, hyperlipidemia, epigenetic dysregulation, genetics [1].However, pathophysiology has not yet been fully...