- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Retinal Diseases and Treatments
- Drug-Induced Ocular Toxicity
- Retinal Imaging and Analysis
- Receptor Mechanisms and Signaling
- Retinal and Macular Surgery
- Regulation of Appetite and Obesity
- Traumatic Ocular and Foreign Body Injuries
- Retinal Development and Disorders
- Intraocular Surgery and Lenses
- Chaos control and synchronization
- Antioxidant Activity and Oxidative Stress
- Hemoglobinopathies and Related Disorders
- Facial Trauma and Fracture Management
- Nonlinear Photonic Systems
- Syphilis Diagnosis and Treatment
- Cellular transport and secretion
- Genomic variations and chromosomal abnormalities
- Traumatic Brain Injury and Neurovascular Disturbances
- Ocular and Laser Science Research
- Cerebral Venous Sinus Thrombosis
- Biochemical Analysis and Sensing Techniques
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
Sun Yat-sen University
2003-2016
Qilu Hospital of Shandong University
2016
Zhongshan Ophthalmic Center, Sun Yat-sen University
2001-2011
National Yang Ming Chiao Tung University
2006
Age-related macular degeneration (AMD) is the leading cause of severe visual loss in aged people. Melatonin has been shown to have capacity control eye pigmentation and thereby regulate amount light reaching photoreceptors, scavenge hydroxyradicals protect retinal pigment epithelium (RPE) cells from oxidative damage. Therefore, it reasonable think that physiological decrease melatonin people may be an important factor RPE dysfunction, which a well known for initiation AMD. Our purpose...
Reports of terminal and interstitial deletions the long arm chromosome 2 are rare in literature.Here, we present a case report concerning Chinese boy with 47,XYY karyotype de novo deletion comprising approximately 5 Mb between 2q35 q36.1, along syndactyly, type III Waardenburg syndrome, congenital heart disease.High-resolution analysis D. Wang et al. Genetics Molecular Research 15 (4): gmr15049060to detect copy number variations was carried out using an Affymetrix microarray platform, genes...
To describe the anticipation and anti-glaucoma drugs response of a Chinese family with juvenile-onset open angle glaucoma (JOAG) caused by Pro370Leu myocilin (MYOC) mutation.Fifteen members three-generation JOAG were recruited to this study. They all underwent ophthalmic common examinations. Patients suspected have got an assessment visual field optical coherence tomography. Intraocular pressures (IOPs) four patients measured at 8, 10, 12, 14, 17 o'clock respectively after using drugs....
Click to increase image sizeClick decrease sizeKey Words: agingepiphysismelatoninthyrotropin releasing hormone
From the Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Science, Guangzhou, China. Reprint requests: Changxian Yi, MD, 510060 PR China; e-mail: [email protected] The authors have no proprietary interest in contents this article.
X-linked juvenile retinoschisis (XLRS) is a major cause of macular degeneration in young men. In this study we analyzed all six exons the XLRS1 gene four sporadic XLRS patients and an affected family China who were recently diagnosed. We found there are five different mutations with containing missense point one having frame-shift deletion. Among these both c.644A > T c.520delC novel have not been previously reported. Moreover second-generation offsprings most third-generation ones to carry...
Uveal effusion syndrome is a rare disease characterized by exudative detachments of the choroid, ciliary body, and retina. Various surgical procedures nonsurgical strategies have been described to treat uveal with limited success. The treatment for remains serious challenge clinicians. To best our knowledge, no previous report has severe patient nanophthalmos treated using an anti-vascular endothelial growth factor agent alone. We here one such case unexpected positive results.A 30-year-old...
With the increasingly extensive application of erectile dysfunction (ED) drugs , it is importance for an ophthalmologist to understand association between these and human eyes. In this study, we retrospectively studied effects ED on eyes, including visual symptoms, ophthalmological electrophysiology, ocular blood flow, intraocular pressure, field, retina, cerebral hemodynamics nervous system retinal vessels, particularly focusing relationship agents nonarteritic ischemic optic neuropathy...
Objective To investigate the impact of detachment and edema acute macular retinal nerve fiber layer on visual prognosis in patients with Vogt-Koyanagi-Harada syndrome(VKHs).Methods A retrospective analysis was performed lesions,visual distribution before after treatment 74 VKHs first attack (108 eyes) whom visited Zhongshan Ophthalmic Center,Sun Yat-sen University from December 2006 to January 2009.The post-treatment vision or without were compared.Results There 53 (71.62%),and 21 (28.38%)...
Objective To evaluate the efficacy and security of therapeutic scheme to patients Vogt-Koyanagi-Harada syndrome.Methods A retrospective analysis was given 108 with syndrome dated from Dec.2006 Jan.2009 on recurrence,medication,visual prognosis course treatment.The visual recurrence first-visit cases transfer-visit were compared.Results Cyclosporin applied in 49.07% patients.38.27% 81.48% first attack recurrent respectively; ≥1.0 better than (P <0.05); rate (5.41%) lower (17.65%)...
Objective To analyze the causes of misdiagnosis acute retinal necrosis syndrome (ARN),and possible critical points in preventing misdiagnosis.Methods Clinical data 81 cases (93 eyes) in-patients with ARN from May 2006 to 2012 Zhongshan Ophthalmic Center,Sun Yat-sen University were retrospectively analyzed.Results The average time first visit after appearance ocular symptoms was 7.03 days (1 21 days),86 eyes (91.36%) misdiagnosed total.There only 7 that correctly diagnosed at initial...
Objective To determine the effect of total vitrectomy treating acute retinal necrosis syn-drome (ARNS).Methods A consecutive 17 eyes human immunodeficiency virus-negative patients with ARNS were surgeried technique between March 2003 and October 2006.There reti-nal detachment (RD)in 13 no RD in 4 eyes.The surgical techniques included vitrectomy, mere-bran-peeling epiretinal membranes necrosing retina relaxing retinotomies/retinectomies,injecting per-flurocarbon liquid, endolaser...