A5035545314- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- COVID-19 Clinical Research Studies
- Gallbladder and Bile Duct Disorders
- Viral-associated cancers and disorders
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Drug-Induced Hepatotoxicity and Protection
- Eosinophilic Esophagitis
- Polyomavirus and related diseases
- Hernia repair and management
- Pregnancy and Medication Impact
- Diet and metabolism studies
- COVID-19 and healthcare impacts
- Renal Diseases and Glomerulopathies
- Medical Imaging and Pathology Studies
- Antifungal resistance and susceptibility
- Pneumocystis jirovecii pneumonia detection and treatment
- Hepatitis Viruses Studies and Epidemiology
- Celiac Disease Research and Management
- Pharmacological Effects of Medicinal Plants
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Long-Term Effects of COVID-19
Brigham and Women's Hospital
2020-2024
Harvard University
2020-2024
Weill Cornell Medicine
2020
Washington DC VA Medical Center
2020
Mayo Clinic in Arizona
2020
Cornell University
2020
Tufts Medical Center
2009-2018
Japan Breast Cancer Research Group
2017
Brown University
2015
Boston Medical Center
2015
Liver injury has been described with COVID-19, and early reports suggested 2%-11% of patients had chronic liver disease (CLD). In this multicentre retrospective study, we evaluated hospitalized adults laboratory-confirmed COVID-19 the impact CLD on relevant clinical outcomes. Of 363 included, 19% CLD, including 15.2% NAFLD. Patients longer length stay. After controlling for age, gender, obesity, cardiac diseases, hypertension, hyperlipidaemia, diabetes pulmonary disorders, NAFLD were...
INTRODUCTION: Liver injury has been described with COVID-19, and early reports suggested 2–11% of patients had chronic liver disease (CLD). However, there are limited on the nature among COVID-19 how underlying CLD influences clinical outcomes. Given high prevalence NAFLD in US, as well metabolic syndrome obesity being potential poor prognostic factors for we hypothesized that CLD, particularly NAFLD, may be associated more severe course worse outcomes COVID-19. We aimed to study effect...
Predicting the efficacy of antiviral treatment hepatitis C virus (HCV) is importance for both patient well-being and health care expense. The expression interferon-stimulated genes (IFN-SGs) in liver was suggested as a marker response to anti-viral therapy. IFN-SGs encode guanosine triphosphate cyclohydrolase 1 (GTPCH), rate-limiting enzyme pteridines biosynthesis. Neopterin, stable byproduct GTPCH-catalyzed reaction, used interferon-induced GTPCH activation. We hypothesized that assessment...
Coronavirus disease 2019 (COVID-19) is associated with elevated liver biochemistries in approximately half of hospitalized patients, many possible etiologies.To assess agreement on the etiology abnormal and diagnostic recommendations COVID-19.Twenty hepatology consultations were reviewed by three senior hepatologists who provided a differential diagnosis recommendations. Kappa primary was calculated.Kappa between 0.10 (p = 0.03). Agreement greater around drug-induced injury 0.51 < 0.0001)...
Aims Although turmeric is commonly ingested and well tolerated, there increasing evidence that over‐the‐counter supplements can cause drug‐induced liver injury. We sought to thoroughly characterise clinicopathological features of patients for whom injury was attributed clinically supplements. Methods results identified 11 via retrospective pathology archive review: 10 females (91%) one male, with a median age 58 years (range = 37–66 years). Six (55%) were asymptomatic abnormal function...
Introduction:Candida esophagitis (CE) is one of the most common opportunistic infections in patients with impaired immunity but also being recognized increasing frequency among without traditional risk factors. While factor for CE immunosuppression related to a disease process or medication, there are variety lesser-known factors that should be acknowledged. The goal this study was therefore retrospectively identify clinical both immunocompromised and immunocompetent an academic hospital...
Purpose: Liver masses comprise of a wide range diseases, from benign focal lesions to malignant liver tumors. in healthy people are often found incidentally, and the majority benign. In patients with cirrhosis or underlying disease, hepatic lesion raises suspicion malignancy. We report case 31-year-old woman who presented 1-month history epigastric pain radiating her right flank, associated bloating anorexia. She had autoimmune hepatitis diagnosed 17 years earlier. A biopsy then was...
Purpose: Primary sclerosing cholangitis (PSC) is associated with increased risk of cholangiocarcinoma (CCA) and, to a lesser extent, hepatocellular carcinoma (HCC). Liver transplantation the only potentially curative treatment in patients end-stage liver disease resulting from PSC. Recurrence has been reported 20-25% within 5-10 years transplantation. Incidence hepatobiliary malignancy who have undergone for PSC not widely literature. We report case 50-year-old male, previously diagnosed at...