A5100450270- Invertebrate Immune Response Mechanisms
- Aquaculture disease management and microbiota
- Neurobiology and Insect Physiology Research
- Advanced MRI Techniques and Applications
- NMR spectroscopy and applications
- Aquaculture Nutrition and Growth
- Bone health and osteoporosis research
- CRISPR and Genetic Engineering
- Developmental Biology and Gene Regulation
- Insect symbiosis and bacterial influences
- Osteoarthritis Treatment and Mechanisms
- Air Quality and Health Impacts
- Identification and Quantification in Food
- Cancer Cells and Metastasis
- Plant Gene Expression Analysis
- Microbial infections and disease research
- Medical Imaging and Analysis
- Digestive system and related health
- Rheumatoid Arthritis Research and Therapies
- Blood disorders and treatments
- Bone Metabolism and Diseases
- Cell Adhesion Molecules Research
- Hippo pathway signaling and YAP/TAZ
- Inflammatory mediators and NSAID effects
- Mesenchymal stem cell research
Institute of Crop Sciences
2024
Chinese Academy of Agricultural Sciences
2020-2024
Jiangsu Agri-animal Husbandry Vocational College
2019-2023
Ministry of Agriculture and Rural Affairs
2019-2022
Zhengzhou University
2022
Chinese Academy of Fishery Sciences
2022
National Institute of Biological Sciences, Beijing
2016-2020
Institute of Plant Protection
2020
Shanghai Ocean University
2019
Montreal Clinical Research Institute
2019
Homeostatic renewal of many adult tissues requires balanced self-renewal and differentiation local stem cells, but the underlying mechanisms are poorly understood. Here we identified a novel feedback mechanism in controlling intestinal regeneration tumorigenesis Drosophila. Sox21a, group B Sox protein, is preferentially expressed committed progenitor named enteroblast (EB) to promote enterocyte differentiation. In Sox21a mutants, EBs do not divide, cannot differentiate properly have...
Magnetization transfer (MT) imaging is one way to indirectly assess pools of protons with fast transverse relaxation. However, conventional MT sequences are not applicable short T 2 tissues such as cortical bone. Ultrashort echo time (UTE) E values low 8 µs can detect signals from different water components in In this study we aim evaluate two‐dimensional UTE‐MT bone and its application assessing porosity measured by micro‐computed tomography (μCT) biomechanical properties. total, 38 human...
Purpose We present three-dimensional ultrashort echo time Cones (3D UTE Cones) techniques for quantification of total water T1 ( ), bound and pore ) in vitro vivo using a 3 Tesla (T) scanner. Methods , were measured with (3D) adiabatic inversion recovery Cone (IR-Cone) sequences. Two-dimensional (2D) nonselective (UTE) techniques, including saturation recovery, variable repetition times (TRs), (IR) preparation approaches compared 3D-Cones on bovine cortical bone samples (n = 8). The 3D...
Bone water exists in different states with the majority bound to organic matrix and mineral, a smaller fraction ‘free’ form pores of cortical bone. In this study, we aimed develop evaluate ultrashort-TE (UTE) MRI techniques for assessment T2*, T1 concentration collagen-bound pore bone using 3-T clinical whole-body scanner. UTE MRI, together an isotope study tritiated distilled (THO–H2O) exchange, as well gravimetric analysis, were performed on ten sectioned bovine samples. addition, 32 human...
We report the three‐dimensional ultrashort‐TE (3D UTE) and adiabatic inversion recovery UTE (IR‐UTE) sequences employing a radial trajectory with conical view ordering for bi‐component T 2 * analysis of bound water ( BW ) pore PW in cortical bone. An interleaved dual‐echo 3D acquisition scheme was developed fast A IR‐UTE multiple spokes per IR imaging. Two‐dimensional (2D were employed comparison. The applied to bovine bone samples n = 6) volunteers using 3‐T scanner. Bi‐component fitting...
Purpose To compare the variation patterns of ADC and T2 values in different age intervertebral disc (IVD) levels, thus to identify their sensitivities assessing level related IVDs changes. Materials Methods The were recorded from 345 69 volunteers. Kendall's correlation analysis was used relationship between T2/ADC mean respectively. one-way variance (ANOVA) with post hoc then applied test differences among IVD levels groups, followed by linear regression (<45 >45 years) values. This study...
Temperature changes have a great impact on fish feeding, intestinal microorganisms, metabolism, and immune function. Therefore, it is necessary to develop effective methods enhance the survival rates growth of under water temperature changes. Lactic acid bacteria (LAB) are promising immunostimulatory feed additive, as demonstrated by their beneficial effects in several species. This study investigated short-term dietary LAB microbiota composition responses crucian carp (Carassius auratus)...
Balanced stem cell self-renewal and differentiation is essential for maintaining tissue homeostasis, but the underlying mechanisms are poorly understood. Here, we identified transcription factor SRY-related HMG-box (Sox) 100B, which orthologous to mammalian Sox8/9/10, as a common target central mediator of EGFR/Ras JAK/STAT signaling pathways that coordinates intestinal (ISC) proliferation during both normal epithelial homeostasis stress-induced repair in Drosophila. The two...
Diapause is a state of arrested growth, which allows insects to adapt diverse environments. Serine protease inhibitors (serpins) play an important role in various physiological processes, including blood coagulation, fibrinolysis, development, complement activation and extracellular matrix remodeling. We hypothesized that serpin may affect energy metabolism thereby control diapause migratory locust (Locusta migratoria) embryos by regulating cascades. A total seven nonredundant genes (named...
SUMMARY Wheat growth process has been experiencing severe challenges arising from the adverse environment. Notably, incidence of Fusarium crown rot (FCR), a soil‐borne disease caused by pseudograminearum ( Fp ), significantly intensified in various wheat‐growing regions, resulting decline grain yield. However, identification wheat varieties and exploration effective gene resources resistant to FCR have not yet accomplished. Here, we screened identified tryptophan metabolism pathway...
Congenital insensitivity to pain with anhidrosis is a rare autosomal recessive disorder. It has been reported that the defect in NTRK1 gene encoding tropomyosin-related kinase A (TrkA) can cause congenital anhidrosis. Nerve growth factor (NGF), product of NGFB, mediates biological effects by binding and activating A. In addition, necdin (encoded NDN) also essential nerve factor–tropomyosin-related pathway. We performed mutation analysis NTRK1, NDN genes Chinese Han 17-year-old female patient...
Ulcer disease has resulted in substantial economic losses eel aquaculture. Yet only scarce information is available on Shewanella algae as a possible causal agent for this disease. In study, virulent strain, temporarily named MY, was isolated from diseased American eel, Anguilla rostrata, suffering ulcer and identified S. through molecular phenotypic methods. A phylogenetic tree constructed to examine MY compare it other known isolates. Besides, isolate exhibited susceptibility...
Ulcer disease has caused significant economic losses in the culture of snakehead fish Ophiocephalus argus (Cantor). Information available on Citrobacter freundii as a possible causal agent for this is scarce. In study, virulent strain, temporarily named GB1, was isolated from diseased suffering ulcer and identified C. through molecular phenotypic methods. A phylogenetic tree constructed to examine isolate GB1 compare it other known isolates. addition, developed resistance aminoglycosides,...
Enteritis has resulted in large economic losses channel catfish aquaculture. Yet only scarce information is available on Plesiomonas shigelloides as a causal agent for this disease. In study, virulent strain, temporarily named BD1, was isolated from diseased suffering enteritis, and identified P. through molecular phenotypic methods. A phylogenetic tree also constructed to determine its taxonomic position. addition, the BD1 isolate developed multiple resistances aminoglycosides, amphenicols,...
In this study, a group of large-scale biofloc shrimp culturing facilities were designed. The bioflocs domesticated by continuously reducing the ratio carbon to feed. bacterial community diversity on 20th, 40th, 60th, and 80th days was analyzed high-throughput sequencing technology. results showed that content (0~16.8 ± 4.3) mL/L, TSS concentration (0~247.46 27.3) total ammonia nitrogen (0~0.28 0.052) mg/L, nitrite (0~4.13 1.42) nitrate (108.57 19.6) mg/L all within safe range Litopenaeus...