A5101536354- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Transplantation: Methods and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Organ and Tissue Transplantation Research
- Vascular Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Cardiac electrophysiology and arrhythmias
- Heart Rate Variability and Autonomic Control
- Cardiac and Coronary Surgery Techniques
- Advanced MRI Techniques and Applications
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Nutrition, Health and Food Behavior
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
Ajou University
2015-2025
Seoul National University Hospital
2025
National University College
2025
New Generation University College
2025
Seoul National University
2015-2025
Macau University of Science and Technology
2024
Karamay Central Hospital
2024
Ajou University Hospital
2013-2022
Stanford Medicine
2014-2018
Stanford University
2014-2018
This study compared the diagnostic performance with adenosine-derived fractional flow reserve (FFR) ≤0.8 of contrast-based FFR (cFFR), resting distal pressure (Pd)/aortic (Pa), and instantaneous wave-free ratio (iFR). objectively identifies lesions that benefit from medical therapy versus revascularization. However, requires maximal vasodilation, usually achieved adenosine. Radiographic contrast injection causes submaximal coronary hyperemia. Therefore, intracoronary could provide an easy...
Stent implantation for coronary ostial lesions is challenging. This study evaluated the feasibility, safety, and immediate procedural results of Osfit™, innovatively designed sirolimus drug-eluting stent delivery system treatment lesions. The Osfit™ has a 5 mm long extended balloon proximal to (bare without mounted stent). When inflated at 1.5 atm, only bare acts like stopper. We technical feasibility in 49 patients with lesion (defined as stenosis within 3 from origin vessel) who had...
The aim of this study is to evaluate the usefulness index microcirculatory resistance (IMR) for predicting myocardial viability and left ventricular (LV) function recovery in acute infarction (AMI).After successful primary percutaneous coronary intervention 40 patients with anterior AMI, IMR was measured using a pressure-temperature sensor-tipped guidewire. Myocardial quantified by 18F-fluorodeoxyglucose (FDG) positron emission tomography 38 patients. Echocardiographic regional wall motion...
The aim of this study is to determine the prognostic value invasively assessing coronary physiology early after heart transplantation.Seventy-four cardiac transplant recipients had fractional flow reserve, index microcirculatory resistance (IMR), and intravascular ultrasound performed down left anterior descending artery soon (baseline) 1 year transplantation. primary end point was cumulative survival free death or retransplantation at a mean follow-up 4.5±3.5 years. event-free significantly...
<h3>Objective</h3> To evaluate whether the addition of cilostazol to dual antiplatelet therapy (DAT, aspirin plus clopidogrel) can attenuate clopidogrel on-treatment platelet reactivity (OPR) in patients with CYP2C19 loss-of-function (LOF) allele. <h3>Methods</h3> In CILON-T randomised trial, were randomly assigned either DAT or triple (TAT, cilostazol). Genotyping cytochrome P450 *2, *3 and *17 was performed OPR measured using VerifyNow P2Y12 assay. Carriers those at least one LOF...
The objective of this study was to assess the relationship between intravascular ultrasound (IVUS) parameters, including volumetric analysis, and fractional flow reserve (FFR).Although it is known that coronary atherosclerosis burden measured by IVUS analysis related with clinical outcomes, its functional significance remains unknown.Both FFR were performed in 206 cases intermediate stenosis left anterior descending artery (LAD). Myocardial ischemia assessed maximal hyperemia induced...
Excoriation disorder, or skin-picking is a compulsive condition that leads to self-inflicted tissue damage. The authors present case of 43-year-old female with large and persistent facial wound exposing the left malar bone remained unresponsive multiple medical interventions. Imaging revealed 4×3x4 cm defect extending into intraoral cavity. Despite surgical debridement reconstruction, dehiscence persisted until psychiatric evaluation confirmed excoriation disorder. Treatment included...
Goldenhar syndrome (GS), also known as oculo-auriculo-vertebral spectrum (OAVS), is a congenital condition affecting the craniofacial region and vertebrae. This report details 21-year-old Korean female with GS, characterized by absence of bilateral mental foramina, who underwent 2-jaw orthognathic surgery genioplasty to address mandibular hypoplasia, asymmetry, severe anterior open bite. Preoperative computed tomography revealed hypoplasia right maxilla left mandible, absent which were...
<b><i>Objective:</i></b> We aimed to assess the ideal cut-off value of minimal lumen area (MLA) by intravascular ultrasound (IVUS) and its diagnostic performance predict ischemia, using a large-scale, pooled analysis. <b><i>Methods:</i></b> Eleven centers worldwide were invited provide their clinical, IVUS fractional flow reserve (FFR) data. A total 881 lesions enrolled. <b><i>Results:</i></b> Angiographic % diameter...
We compared the efficacy and safety of valsartan rosuvastatin combination therapy with each treatment alone in hypercholesterolemic hypertensive patients.Patients who met inclusion criteria were randomized to receive 1 following 2-month drug regimens: 160 mg plus 20 mg, placebo, or placebo. The primary variables change sitting diastolic blood pressure (sitDBP) systolic (sitSBP), percentage low-density lipoprotein-cholesterol (LDL-C) combination, valsartan, groups. Adverse events (AEs) during...
Efficacy of combined intravascular ultrasound (IVUS) parameters in functional significance prediction and discrepancy between IVUS fractional flow reserve (FFR) have not been well defined. This study therefore aimed to: 1) evaluate the diagnostic accuracy parameters, namely minimal lumen area (MLA) percent plaque burden (%PB), coronary artery stenosis; 2) define factors that affect relation FFR value parameters.At 11 international centres, measurements were concurrently performed 945 major...
Background:The functional significance of an intermediate coronary lesion is crucial for determining the treatment strategy, but age-related changes in cardiovascular function could affect epicardial stenosis. The aim this study was therefore to investigate impact age on fractional flow reserve (FFR) measurements patients with artery disease (CAD).Methods and Results:Intracoronary pressure intravascular ultrasound (IVUS) were performed 178 left anterior descending arteries morphological...
Microvascular function is a useful predictor of left ventricular functional changes in patients with ST-segment elevation myocardial infarction (STEMI). We evaluated the usefulness hyperemic microvascular resistance index (hMVRI) for predicting long-term major adverse cardiovascular events (MACEs) STEMI assessed immediately after primary percutaneous coronary intervention (PCI).hMVRI were 145 first acute treated PCI using an intracoronary Doppler wire. hMVRI was defined as ratio mean aortic...