A5101602570- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Pituitary Gland Disorders and Treatments
- Gallbladder and Bile Duct Disorders
- Lung Cancer Research Studies
- Advanced Radiotherapy Techniques
- Diabetes and associated disorders
- Diabetes Management and Research
- Pancreatic function and diabetes
- Artificial Intelligence in Healthcare and Education
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Pancreatitis Pathology and Treatment
- Brain Metastases and Treatment
- Head and Neck Surgical Oncology
- Radiomics and Machine Learning in Medical Imaging
- Breast Cancer Treatment Studies
- Medical Imaging and Analysis
- Pancreatic and Hepatic Oncology Research
- Anatomy and Medical Technology
- Abdominal Surgery and Complications
- Adrenal and Paraganglionic Tumors
- Thyroid and Parathyroid Surgery
- Pulmonary Hypertension Research and Treatments
University of Southern California
2023-2025
Neurological Surgery
2025
Los Angeles Medical Center
2025
State Street (United States)
2025
Institut d'Investigació Sanitària Pere Virgili
2014-2024
University Health Network
2024
Baxter (United States)
2024
University of Toronto
2023-2024
St. Michael's Hospital
2024
Baxter (Switzerland)
2024
OBJECTIVE To compare races/ethnicities for characteristics, at type 1 diabetes diagnosis and during the first 3 years postdiagnosis, known to influence long-term health outcomes. RESEARCH DESIGN AND METHODS We analyzed 927 Pediatric Diabetes Consortium (PDC) participants <19 old (631 non-Hispanic white [NHW], 216 Hispanic, 80 African American [AA]) diagnosed with followed a median of 3.0 (interquartile range 2.2–3.6). Demographic clinical data were collected from medical records...
Abstract Background The management of locally advanced breast cancer poses significant challenges, with contemporary strategies involving an approach that combines systemic and local treatment. current study was performed to validate the clinical impression locoregional recurrences have become increasingly uncommon after standardized multimodal treatment protocol.Please check confirm authors their respective affiliations been correctly identified amend if necessary.All are correct. Methods A...
Methylation of the O6-methylguanine-DNA methyltransferase (MGMT) promoter is an important prognostic marker in glioblastoma (GBM); however, its implementation clinical practice remains understudied. Here, we assessed prevalence MGMT methylation status among GBM patients United States. Additionally, evaluated treatment practices and survival outcomes according to status. The National Cancer Database was queried identify all adult U.S. (≥ 18 years) diagnosed with IDH-wildtype between 2018...
Abstract Objective Nonfunctioning pituitary adenomas (NFPA) are common, benign lesions of the gland. The endoscopic endonasal approach (EEA) has improved their treatment. Large multi-center data across different healthcare systems on outcomes following EEA resection NFPA limited. We aimed to provide highly generalizable benchmark from an international, review for resection. Methods Institution-level symptoms, tumor and intraoperative characteristics, complications, long-term were obtained...
OBJECTIVE Pituitary adenomas (PAs) are common lesions that often present with endocrinopathy and/or visual symptoms. Classification of PAs has historically been based on functional status and histopathological staining anterior pituitary hormones. In 2017, the WHO revised classification PAs, establishing cell lineages identified by transcription factors (TFs) PIT1, TPIT, SF1. The clinical behavior PA subtypes TF typing, including growth patterns, response to treatment, recurrence rates, is...
OBJECTIVE The goal of this study was to characterize the pre-, peri-, and postoperative risk factors associated with early hyponatremia (defined as a serum sodium level < 135 mEq/L on or before day [POD] 3) following transsphenoidal pituitary surgery. METHODS This retrospective performed using single-institution database for patients undergoing surgery adenoma (PA). Serum values were collected routinely throughout period. Uni- multivariable statistical analyses identify independent...
Population-based studies of histologically confirmed glioblastoma without molecular classification have demonstrated the doubling 3-year overall survival (OS) since 2005 despite minimal additions to treatment armamentarium. The authors aimed evaluate whether changes in tumor characteristics and patterns were associated with outcomes. Additionally, sought elucidate disparities access established novel therapeutic modalities for patients glioblastoma. queried all diagnosed by histology...
Robust economic evaluations are needed to identify efficient strategies for lung cancer prevention that combine brief and intensive smoking cessation intervention programmes with screening using low-dose computed tomography (LDCT) at different ages, frequencies, coverages. We aimed assess the cost-effectiveness of approaches combined in European context a population level from societal perspective.A microsimulation model describes natural history incorporates several was developed....
Abstract Background Metabolic reprogramming and abnormal glucose metabolism are hallmarks of head neck squamous cell carcinoma (HNSCC). Certain oncogenes can promote cancer‐related metabolic changes, but understanding their crosstalk in HNSCC biology treatment is essential for identifying predictive biomarkers developing target therapies. Methods We assessed the value survivin/BIRC5 as a radioresistance factor potentially modulated by predicting therapeutic sensitivity prognosis cohort 32...
Abstract Background Complicated acute biliary calculous disease poses clinical challenges. The European Society of Trauma and Emergency Surgery (ESTES) snapshot audit complicated aims to make novel comparisons between self-reported institutional adherence the Tokyo guidelines (TG18) ‘real-world’ contemporary practice across Europe. Methods A preplanned analysis a prospective observational multicentre that captured patients undergoing emergency admission for (complicated cholecystitis,...
Abstract Background Accrued comorbidities are perceived to increase operative risk. Surgeons may offer treatments less often their older patients with acute complicated calculous biliary disease (ACCBD). We set out capture ACCBD incidence in across Europe and the currently used treatment algorithms. Methods The European Society of Trauma Emergency Surgery (ESTES) undertook a snapshot audit undergoing emergency hospital admission for between October 1 31 2018, comparing under ≥ 65 years....
INTRODUCTION: Artificial intelligence (AI) and machine learning (ML) have transformed healthcare, with applications in various specialized medical fields. Neurosugery can benefit from AI surgical planning, predicting patient outcomes, analyzing neuroimaging data. GPT-4, an updated advanced language model by OpenAI additional training parameters, has exhibited exceptional performance on standardized exams. METHODS: GPT-4's was examined 643 Congress of Neurological Suregons (CNS)...
Acute complications of biliary calculi are common, morbid, and complex to manage. Variability exists in the techniques utilized treat these conditions at an individual surgeon unit level.To identify, through international prospective nonrandomized cohort study, epidemiology areas practice variability management acute complicated calculous disease (ACCBD) correlate them against reported outcomes.A preplanned analysis European Society Trauma Emergency Surgery (ESTES) 2018 Complicated Biliary...
Suprasellar tumors, particularly pituitary adenomas (PAs), commonly present with visual decline, and the endoscopic endonasal transsphenoidal approach (EETA) is primary management for optic apparatus decompression. Patients presenting complete preoperative monocular blindness comprise a high-risk subgroup, given concern blindness. This retrospective cohort study evaluates outcomes after EETA patients PA
<title>Abstract</title> Purpose After the Tokyo 2018 guidelines (TG2018) were published, evidence from CHOCOLATE RCT supported early cholecystectomy for acute cholecystitis (AC), even in high-risk patients. This study aims to investigate AC management at our tertiary care center years following these publications. Methods A retrospective cohort was performed of patients admitted 2018–2023. severity graded using TG2018 definitions. Comorbidities summarized Charlson Comorbidity Index (CCI) and...
<h3>Background</h3> Emotional stability is an important dimension of personality, therefore any involvement in this area should be considered as important. Psychological sleep disorders rheumatoid arthritis (RA) are poorly described literature. <h3>Objectives</h3> The aim study was to describe psychological and disturbances using CIE-10 classification a population with RA possible correlation disease activity. <h3>Methods</h3> A descriptive cross-sectional performed specialized clinic...