- Biochemical Analysis and Sensing Techniques
- Advanced Chemical Sensor Technologies
- Olfactory and Sensory Function Studies
- Natural Products and Biological Research
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- DNA and Nucleic Acid Chemistry
- Ion Channels and Receptors
- Seed and Plant Biochemistry
- Natural product bioactivities and synthesis
- Advanced biosensing and bioanalysis techniques
- Analytical Chemistry and Chromatography
- Plant biochemistry and biosynthesis
- Insect and Pesticide Research
- Phytochemistry and Biological Activities
- Heavy metals in environment
- Insect Pest Control Strategies
- Saffron Plant Research Studies
- Flowering Plant Growth and Cultivation
- Advances in Cucurbitaceae Research
- Microbial Metabolites in Food Biotechnology
- Chromium effects and bioremediation
- Phytochemical compounds biological activities
- Moringa oleifera research and applications
- Plant Parasitism and Resistance
University of Milan
2015-2025
Weatherford College
2022
GTx (United States)
2008
Cannabidiol (CBD)-based oil preparations are becoming extremely popular, as CBD has been shown to have beneficial effects on human health. CBD-based not unambiguously regulated under the European legislation, is considered a controlled substance. This means that companies can produce and distribute products derived from non-psychoactive hemp varieties, providing an easy access this advantageous cannabinoid. leaves consumers with no legal quality guarantees. The objective of project was...
Bitter taste is an innately aversive modality that considered to protect animals from consuming toxic compounds. Yet, bitterness not always noxious and some bitter compounds have beneficial effects on health. Hundreds of were reported (and are accessible via the BitterDB http://bitterdb.agri.huji.ac.il/dbbitter.php ), but numerous additional molecules still unknown. The dramatic chemical diversity bitterants makes prediction a difficult task. Here we present machine learning classifier,...
The hypoglycemic effect in humans of Moringa oleifera (MO) leaf powder has, to date, been poorly investigated. We assessed the chemical composition MO produced at Saharawi refugee camps, its vitro ability inhibit α-amylase activity, and sensory acceptability food. then evaluated on postprandial glucose response by randomly administering, 2 different days, a traditional meal supplemented with 20 g (MOR20), or not (control meal, CNT), 17 diabetics 10 healthy subjects. Capillary glycaemia was...
In this study, hydrochar (HC), a carbon-rich product originated from hydrothermal conversion treatment (HTC), was obtained wastes of the wine and dairy industries. The effect mixing secondary char compost tested, before after aerobic (COM) HC at increasing doses (from 15 to 75 Mg ha-1 DM), in an effort lower phytotoxicity due potential phytotoxic compounds char. results indicated that, stabilization, mix HC/COM able double plant growth comparison COM alone. presence easily degradable organic...
: Propolis is used as folk medicine due to its spectrum of alleged biological and pharmaceutical properties it a complex matrix not still totally characterized. Two batches propolis coming from two different environments (plains Po Valley the hilly Ligurian-Piedmont Apennines) Northern Italy were characterized using analytical methods: Spectrophotometric analysis phenols, flavones flavonols, DPPH radical scavenging activity, HPLC, NMR, HSPME GC-MS HPLC-MS Orbitrap. Balsam moisture content...
Moringa oleifera Lam. is a tropical plant widely used in traditional medicines and as food supplement. It characterized by the presence of glucosinolates isothiocyanates; stable isothiocyanate 4-[(α-l-rhamnosyloxy)benzyl]isothiocyanate (moringin) has been studied for its bioactivity hypoglycemic, antimicrobial, anticancer particular involvement nociception neurogenic pain. extracts pure moringin were submitted to vitro assays with somatosensory TRPA1 ion channel, proving that potent...
Food compounds with a bitter taste have role in human health, both for their capability to influence food choice and preferences possible systemic effect due the modulation of extra-oral receptors (TAS2Rs). Investigating interaction TAS2Rs is key step unravel complex effects on health pave way rationally design new additives formulation or drugs. Here, we propose collection compounds, which vitro activity data against are available. The patterns TAS2R subtype-specific agonists were analyzed...
Natural products are a rich source of bioactive molecules that have potential pharmacotherapeutic applications. In this study, we focused on Artemisia annua (A. annua) and its enriched extracts which were biologically evaluated in vitro as virucidal, antiviral, antioxidant agents, with application against the COVID-19 infection. The crude extract showed antiviral effects concentrations did not affect cell viability. Scopoletin, arteannuin B artemisinic acid (single fractions isolated from A....
Food plants are the basis of human nutrition, but, in contaminated places, they can uptake contaminants. Environmental contamination and climate change modify food quality; generally, have a negative impact on imply risks to health. Heavy metals, like lead, arsenic, cadmium, chromium, be present at various environmental levels (soil, water, atmosphere), widely distributed world. carry out heavy metal bioaccumulation, defense pathway for plants, which is different every plant species....
Ruta graveolens (rue) is a spontaneous plant in the Mediterranean area with strong aroma and very intense bitter taste, used gastronomy folk medicine. From leaves, stems fruits of rue, we isolated rutin, rutamarin, three furanocoumarins, two quinolinic alkaloids, dicoumarin long chain ketones. Bitter taste chemesthetic properties have been evaluated by vitro assays twenty receptors TAS2R family four TRP ion channels involved gustation nociception. Among skimmianine was active as specific...
Fermentation represents a valuable and cost-effective approach for food stabilisation nutritional improvement. Tempeh is an example of soybean solid-state fermentation. In this work, we investigated the possibility producing tempeh analogue containing high amounts vitamin B12 using seeds three different species legume lupin, namely Lupinus albus, L. angustifolius mutabilis, with Rhizopus oligosporus Propionibacterium freudenreichii cofermentation. Synergic effects in increasing up to 1230...
Plastic materials are widely used in geotechnical engineering, especially as geosynthetics. The use of plastic-based products involves serious environmental risks caused by their degradation. Innovative research has been focusing on biodegradable polymers natural origin, poly(lactic acid) (PLA), to reduce the plastics. This study aims explore potentiality biopolymers for production geogrids, measuring chemical and mechanical characteristics raw prototype samples, similar those available...
The COVID-19 pandemic represents an unprecedented global emergency. Despite all efforts, remains a threat to public health, due the complexity of mass vaccination programs, lack effective drugs, and emergence new variants. A link has recently been found between risk developing severe infection high level oxidative stress. In this context, we have focused our attention on natural compounds with aim finding molecules capable acting through dual virucidal-antioxidant mechanism. particular,...
Caigua (Cyclanthera pedata (L.) Schrad.) is a traditional herbal remedy traditionally used in Latin America for its health benefits and to treat metabolic disorders, including diabetes. Despite interest use, the phytochemical properties of caigua’s secondary metabolites are poorly known. This study aimed isolate main flavone glycosides from leaves caigua landrace cultivated Camonica Valley (Italy) using flash chromatography evaluate their potential activity toward peroxisome...
Orthoherpesviridae is a large family of enveloped DNA virus. Among the most significant animal-infecting viruses are bovine alphaherpesvirus 1 (BoAHV1), caprine (CpAHV1) and equid (EqAHV1). Research into new methods to combat herpesvirus infections ongoing. The aim this study was evaluate antiviral activity three extracts Helleborus bocconei roots against BoAHV1, CpAHV1 EqAHV1. were air-dried, extracted with methanol (MeOH) then partitioned between n-butanol (n-BuOH) water. All tested for...